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Matthieu G. Gagnon
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引用次数
引用次数
年份
Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design
J Lin, D Zhou, TA Steitz, YS Polikanov, MG Gagnon
Annual Review of Biochemistry 87, 2018
2912018
The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
RN Roy, IB Lomakin, MG Gagnon, TA Steitz
Nature Structural & Molecular Biology 22 (6), 466-469, 2015
1862015
Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition
MG Gagnon, RN Roy, IB Lomakin, T Florin, AS Mankin, TA Steitz
Nucleic acids research 44 (5), 2439-2450, 2016
1722016
Conformational changes of elongation factor G on the ribosome during tRNA translocation
J Lin, MG Gagnon, D Bulkley, TA Steitz
Cell 160 (1), 219-227, 2015
1422015
Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome
MG Gagnon, SV Seetharaman, D Bulkley, TA Steitz
Science 335 (6074), 1370-1372, 2012
1322012
Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome
MG Gagnon, J Lin, D Bulkley, TA Steitz
Science 345 (6197), 684-687, 2014
482014
GU receptors of double helices mediate tRNA movement in the ribosome.
MG Gagnon, SV Steinberg
RNA 8 (7), 873-877, 2002
412002
Structural basis for ribosome recycling by RRF and tRNA
D Zhou, T Tanzawa, J Lin, MG Gagnon
Nature Structural & Molecular Biology 27 (1), 25-32, 2020
342020
Study of the functional interaction of the 900 tetraloop of 16S ribosomal RNA with helix 24 within the bacterial ribosome
F Bélanger, MG Gagnon, SV Steinberg, PR Cunningham, ...
Journal of molecular biology 338 (4), 683-693, 2004
292004
Elongation factor 4 remodels the A-site tRNA on the ribosome
MG Gagnon, J Lin, TA Steitz
Proceedings of the National Academy of Sciences 113 (18), 4994-4999, 2016
232016
The adenosine wedge: A new structural motif in ribosomal RNA
MG Gagnon, SV Steinberg
RNA 16 (2), 375-381, 2010
182010
Mapping of the RNA recognition site of Escherichia coli ribosomal protein S7.
F Robert, M Gagnon, D Sans, S Michnick, L Brakier-Gingras
RNA 6 (11), 1649-1659, 2000
182000
Close packing of helices 3 and 12 of 16 S rRNA is required for the normal ribosome function
MG Gagnon, A Mukhopadhyay, SV Steinberg
Journal of Biological Chemistry 281 (51), 39349-39357, 2006
152006
Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
RS Basu, MB Sherman, MG Gagnon
Nature communications 13 (1), 3388, 2022
122022
Antimicrobial peptides targeting bacterial ribosome
IB Lomakin, MG Gagnon, TA Steitz
Oncotarget 6 (22), 18744, 2015
62015
A new family of bacterial ribosome hibernation factors
K Helena-Bueno, MY Rybak, CL Ekemezie, R Sullivan, CR Brown, ...
Nature 626 (8001), 1125-1132, 2024
52024
Mechanisms of ribosome recycling in bacteria and mitochondria: a structural perspective
SM Seely, MG Gagnon
RNA biology 19 (1), 662-677, 2022
52022
Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome
SM Seely, NP Parajuli, A De Tarafder, X Ge, S Sanyal, MG Gagnon
Nature Communications 14 (1), 4666, 2023
42023
Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin
MN Paranjpe, VI Marina, AA Grachev, TP Maviza, OA Tolicheva, ...
Nucleic Acids Research 51 (1), 449-462, 2023
42023
Mechanistic insights into the alternative ribosome recycling by HflXr
SM Seely, RS Basu, MG Gagnon
Nucleic Acids Research 52 (7), 4053-4066, 2024
22024
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