Lung epithelium damage in COPD–an unstoppable pathological event? S Hadzic, CY Wu, S Avdeev, N Weissmann, RT Schermuly, D Kosanovic Cellular signalling 68, 109540, 2020 | 47 | 2020 |
NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD M Seimetz, N Sommer, M Bednorz, O Pak, C Veith, S Hadzic, M Gredic, ... Nature Metabolism 2 (6), 532-546, 2020 | 30 | 2020 |
SPARC, a novel regulator of vascular cell function in pulmonary hypertension C Veith, I Vartürk-Özcan, M Wujak, S Hadzic, CY Wu, F Knoepp, S Kraut, ... Circulation 145 (12), 916-933, 2022 | 27 | 2022 |
Amelioration of elastase‐induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice A Fysikopoulos, M Seimetz, S Hadzic, F Knoepp, CY Wu, K Malkmus, ... British Journal of Pharmacology 178 (1), 152-171, 2021 | 24 | 2021 |
Myeloid-cell-specific deletion of inducible nitric oxide synthase protects against smoke-induced pulmonary hypertension in mice M Gredic, CY Wu, S Hadzic, O Pak, R Savai, B Kojonazarov, S Doswada, ... European Respiratory Journal 59 (4), 2022 | 19 | 2022 |
Adenylate kinase 4—a key regulator of proliferation and metabolic shift in human pulmonary arterial smooth muscle cells via akt and HIF-1α signaling pathways M Wujak, C Veith, CY Wu, T Wilke, ZI Kanbagli, T Novoyatleva, ... International Journal of Molecular Sciences 22 (19), 10371, 2021 | 16 | 2021 |
The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension S Hadzic, CY Wu, M Gredic, B Kojonazarov, O Pak, S Kraut, N Sommer, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 320 (5 …, 2021 | 14 | 2021 |
Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung L Gouveia, S Kraut, S Hadzic, E Vazquéz-Liébanas, B Kojonazarov, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 318 (4 …, 2020 | 13 | 2020 |
Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations ET Roxlau, O Pak, S Hadzic, CF Garcia-Castro, M Gredic, CY Wu, ... European Respiratory Journal 61 (6), 2023 | 8 | 2023 |
CEACAM6 as a Novel Therapeutic Target to Boost HO-1—mediated Antioxidant Defense in COPD CY Wu, A Cilic, O Pak, RC Dartsch, J Wilhelm, M Wujak, K Lo, M Brosien, ... American Journal of Respiratory and Critical Care Medicine 207 (12), 1576-1590, 2023 | 4 | 2023 |
Fibroblast growth factor 10 reverses cigarette smoke-and elastase-induced emphysema and pulmonary hypertension in mice S Hadzic, CY Wu, M Gredic, O Pak, E Loku, S Kraut, B Kojonazarov, ... European Respiratory Journal 62 (5), 2023 | 2 | 2023 |
CEACAM6 impedes the HO-1-mediated defence against nitrosative/oxidative stress in COPD CY Wu, S Hadzic, RC Dartsch, O Pak, J Wilhelm, M Wujak, N Sommer, ... C65. COPD: PRE-CLINICAL MODELS AND MECHANISMS, A4629-A4629, 2022 | 1 | 2022 |
Role of adenylate kinase 4 as a new metabolic regulator of pulmonary artery smooth muscle cells under hypoxia M Wujak, T Wilke, A Weiss, M Brosien, CY Wu, RT Schermuly, ... European Respiratory Journal 54 (suppl 63), 2019 | 1 | 2019 |
Exploring the Therapeutic Potential of Fibroblast Growth Factor 10 Treatment in Elastase-induced Pulmonary Hypertension and Emphysema S Hadzic, E Loku, CY Wu, M Gierhardt, N Ciancio del Giudice, ... B70. COPD IN THE SPOTLIGHT: INSIGHTS INTO DISEASE PATHOGENESIS, A4317-A4317, 2024 | | 2024 |
Mitochondrial Cytochrome C Oxidase Subunit 4 Isoform 2 Promotes Murine Smoke-induced Pulmonary Inflammation and Emphysema-Therapeutic Potential of ROS Inhibition C Garcia, VS Balasubramanian Lakshmi, O Pak, S Hadzic, C Nardiello, ... A108. COPD PATHOGENESIS: OPENING THE PANDORA BOX, A2954-A2954, 2024 | | 2024 |
The Role of CEACAM6/HO-1 Axis in a Mouse Model of Cigarette Smoke-induced Lung Injury CY Wu, H Treis, A Cilic, K Lo, N Sommer, HA Ghofrani, RT Schermuly, ... B70. COPD IN THE SPOTLIGHT: INSIGHTS INTO DISEASE PATHOGENESIS, A4318-A4318, 2024 | | 2024 |
The Role of DUOX1 in the Development of Cigarette Smoke-induced Emphysema and Pulmonary Hypertension E Loku, V Sharma, CY Wu, C Nuguri, M Gredic, S Kraut, B Kojonazarov, ... A101. FULL METAL JACKET TARGETING COPD AND CHRONIC AIRWAYS DISEASE, A2784-A2784, 2024 | | 2024 |
Unravelling susceptibility to COPD: insights from a novel in vitro model to potential therapeutic targets C Wu, A Cilic, K Lo, H Watz, F Pedersen, W Seeger, F Grimminger, ... ERJ Open Research 10 (suppl 14), 2024 | | 2024 |
Developmental fibroblast growth factor 10 in pathogenesis and reversion of emphysema and PH in COPD S Hadzic, E Loku, C Wu, M Gredic, O Pak, M Gierhardt, J Wilhelm, ... ERJ Open Research 10 (suppl 14), 2024 | | 2024 |
Cell-specific Noxo1 Deletion in a Mouse Model of Cigarette Smoke-induced Emphysema and Pulmonary Hypertension S Doswada, CY Wu, B Kojonazarov, RP Brandes, F Grimminger, ... C109. EVEN BETTER THAN THE REAL THING: ADVANCED MODELS OF LUNG DISEASE …, 2023 | | 2023 |