The conserved KMN network constitutes the core microtubule-binding site of the kinetochore IM Cheeseman, JS Chappie, EM Wilson-Kubalek, A Desai Cell 127 (5), 983-997, 2006 | 1159 | 2006 |
Phylogenetic analysis and structural modeling of SARS-CoV-2 spike protein reveals an evolutionary distinct and proteolytically sensitive activation loop JA Jaimes, NM André, JS Chappie, JK Millet, GR Whittaker Journal of molecular biology 432 (10), 3309-3325, 2020 | 500 | 2020 |
G domain dimerization controls dynamin's assembly-stimulated GTPase activity JS Chappie, S Acharya, M Leonard, SL Schmid, F Dyda Nature 465 (7297), 435-440, 2010 | 342 | 2010 |
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke JS Chappie, JA Mears, S Fang, M Leonard, SL Schmid, RA Milligan, ... Cell 147 (1), 209-222, 2011 | 257 | 2011 |
The dynamin middle domain is critical for tetramerization and higher‐order self‐assembly R Ramachandran, M Surka, JS Chappie, DM Fowler, TR Foss, BD Song, ... The EMBO journal 26 (2), 559-566, 2007 | 208 | 2007 |
Electrostatic tuning of ion conductance in potassium channels CM Nimigean, JS Chappie, C Miller Biochemistry 42 (31), 9263-9268, 2003 | 144 | 2003 |
An intramolecular signaling element that modulates dynamin function in vitro and in vivo JS Chappie, S Acharya, YW Liu, M Leonard, TJ Pucadyil, SL Schmid Molecular biology of the cell 20 (15), 3561-3571, 2009 | 114 | 2009 |
A dynamin mutant defines a superconstricted prefission state AC Sundborger, S Fang, JA Heymann, P Ray, JS Chappie, JE Hinshaw Cell reports 8 (3), 734-742, 2014 | 104 | 2014 |
Building a fission machine–structural insights into dynamin assembly and activation JS Chappie, F Dyda Journal of cell science 126 (13), 2773-2784, 2013 | 78 | 2013 |
The structure of a eukaryotic nicotinic acid phosphoribosyltransferase reveals structural heterogeneity among type II PRTases JS Chappie, JM Cànaves, GW Han, CL Rife, Q Xu, RC Stevens Structure 13 (9), 1385-1396, 2005 | 47 | 2005 |
Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation response SG Murphy, L Alvarez, MC Adams, S Liu, JS Chappie, F Cava, T Dörr MBio 10 (1), 10.1128/mbio. 02620-18, 2019 | 41 | 2019 |
Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage CJ Schiltz, A Lee, EA Partlow, CJ Hosford, JS Chappie Nucleic Acids Research 47 (17), 9448-9463, 2019 | 36 | 2019 |
The structural biology of the dynamin‐related proteins: New insights into a diverse, multitalented family MGJ Ford, JS Chappie Traffic 20 (10), 717-740, 2019 | 34 | 2019 |
Diffusible signal factors act through AraC-type transcriptional regulators as chemical cues to repress virulence of enteric pathogens EM Bosire, CR Eade, CJ Schiltz, AJ Reid, J Troutman, JS Chappie, ... Infection and immunity 88 (10), 10.1128/iai. 00226-20, 2020 | 27 | 2020 |
Cyclin N-terminal domain-containing-1 coordinates meiotic crossover formation with cell-cycle progression in a cyclin-independent manner S Gray, ER Santiago, JS Chappie, PE Cohen Cell reports 32 (1), 2020 | 21 | 2020 |
A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex EA Partlow, RW Baker, GM Beacham, JS Chappie, AE Leschziner, ... Elife 8, e50003, 2019 | 21 | 2019 |
The full-length structure of Thermus scotoductus OLD defines the ATP hydrolysis properties and catalytic mechanism of Class 1 OLD family nucleases CJ Schiltz, MC Adams, JS Chappie Nucleic Acids Research 48 (5), 2762-2776, 2020 | 19 | 2020 |
The amino acid linker between the endonuclease and helicase domains of adeno-associated virus type 5 Rep plays a critical role in DNA-dependent oligomerization JE Maggin, JA James, JS Chappie, F Dyda, AB Hickman Journal of virology 86 (6), 3337-3346, 2012 | 18 | 2012 |
The structure of the Thermococcus gammatolerans McrB N-terminal domain reveals a new mode of substrate recognition and specificity among McrB homologs CJ Hosford, AQ Bui, JS Chappie Journal of Biological Chemistry 295 (3), 743-756, 2020 | 16 | 2020 |
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture NV Varlakhanova, FJD Alvarez, TM Brady, BA Tornabene, CJ Hosford, ... Journal of Cell Biology 217 (10), 3608-3624, 2018 | 15 | 2018 |