| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 1180 | 2013 |
| The molecular details of cytokine signaling via the JAK/STAT pathway R Morris, NJ Kershaw, JJ Babon Protein Science 27 (12), 1984-2009, 2018 | 710 | 2018 |
| Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014 | 576 | 2014 |
| Leukemia inhibitory factor (LIF) NA Nicola, JJ Babon Cytokine & growth factor reviews 26 (5), 533-544, 2015 | 457 | 2015 |
| The molecular basis of JAK/STAT inhibition by SOCS1 NPD Liau, A Laktyushin, IS Lucet, JM Murphy, S Yao, E Whitlock, ... Nature communications 9 (1), 1558, 2018 | 382 | 2018 |
| The molecular regulation of Janus kinase (JAK) activation JJ Babon, IS Lucet, JM Murphy, NA Nicola, LN Varghese Biochemical Journal 462 (1), 1-13, 2014 | 379 | 2014 |
| CIS is a potent checkpoint in NK cell–mediated tumor immunity RB Delconte, TB Kolesnik, LF Dagley, J Rautela, W Shi, EM Putz, ... Nature immunology 17 (7), 816-824, 2016 | 345 | 2016 |
| Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity JJ Babon, NJ Kershaw, JM Murphy, LN Varghese, A Laktyushin, ... Immunity 36 (2), 239-250, 2012 | 322 | 2012 |
| TLR7 gain-of-function genetic variation causes human lupus GJ Brown, PF Cañete, H Wang, A Medhavy, J Bones, JA Roco, Y He, ... Nature 605 (7909), 349-356, 2022 | 316 | 2022 |
| SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition NJ Kershaw, JM Murphy, NPD Liau, LN Varghese, A Laktyushin, ... Nature structural & molecular biology 20 (4), 469-476, 2013 | 315 | 2013 |
| A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D ... Biochem. J 457 (2), 323-334, 2014 | 280 | 2014 |
| Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections X Lauth, JJ Babon, JA Stannard, S Singh, V Nizet, JM Carlberg, ... Journal of Biological Chemistry 280 (10), 9272-9282, 2005 | 249 | 2005 |
| Inhibition of IL-6 family cytokines by SOCS3 JJ Babon, LN Varghese, NA Nicola Seminars in immunology 26 (1), 13-19, 2014 | 231 | 2014 |
| Suppression of cytokine signaling: the SOCS perspective EM Linossi, JJ Babon, DJ Hilton, SE Nicholson Cytokine & growth factor reviews 24 (3), 241-248, 2013 | 220 | 2013 |
| The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability JJ Babon, EJ McManus, S Yao, DP DeSouza, LA Mielke, NS Sprigg, ... Molecular cell 22 (2), 205-216, 2006 | 202 | 2006 |
| Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein C Alfano, D Sanfelice, J Babon, G Kelly, A Jacks, S Curry, MR Conte Nature structural & molecular biology 11 (4), 323-329, 2004 | 181 | 2004 |
| The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression JJ Babon, JK Sabo, JG Zhang, NA Nicola, RS Norton Journal of molecular biology 387 (1), 162-174, 2009 | 161 | 2009 |
| Structure and function of the SPRY/B30. 2 domain proteins involved in innate immunity AA D'Cruz, JJ Babon, RS Norton, NA Nicola, SE Nicholson Protein Science 22 (1), 1-10, 2013 | 157 | 2013 |
| The biology and mechanism of action of suppressor of cytokine signaling 3 JJ Babon, NA Nicola Growth factors 30 (4), 207-219, 2012 | 143 | 2012 |
| Stabilization of neurotoxic soluble β-sheet-rich conformations of the Alzheimer's disease amyloid-β peptide DJ Tew, SP Bottomley, DP Smith, GD Ciccotosto, J Babon, MG Hinds, ... Biophysical journal 94 (7), 2752-2766, 2008 | 128 | 2008 |
