The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation Z Li, J Guo, Y Wu, Q Zhou Nucleic acids research 41 (1), 277-287, 2013 | 348 | 2013 |
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation H Lu, Z Li, Y Xue, U Schulze-Gahmen, JR Johnson, NJ Krogan, T Alber, ... Proceedings of the National Academy of Sciences 111 (1), E15-E24, 2014 | 84 | 2014 |
The ubiquitin ligase Siah1 controls ELL2 stability and formation of super elongation complexes to modulate gene transcription M Liu, J Hsu, C Chan, Z Li, Q Zhou Molecular cell 46 (3), 325-334, 2012 | 74 | 2012 |
Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency Z Li, J Wu, L Chavez, R Hoh, SG Deeks, SK Pillai, Q Zhou PLoS pathogens 15 (1), e1007498, 2019 | 59 | 2019 |
Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription H Lu, Z Li, W Zhang, U Schulze-Gahmen, Y Xue, Q Zhou Nucleic Acids Research 43 (12), 5868-5879, 2015 | 59 | 2015 |
The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency Z Li, U Mbonye, Z Feng, X Wang, X Gao, J Karn, Q Zhou PLoS pathogens 14 (4), e1007012, 2018 | 55 | 2018 |
Viral–host interactions that control HIV-1 transcriptional elongation H Lu, Z Li, Y Xue, Q Zhou Chemical reviews 113 (11), 8567-8582, 2013 | 50 | 2013 |
Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription S Qi, Z Li, U Schulze-Gahmen, G Stjepanovic, Q Zhou, JH Hurley Nature Communications 8 (1), 14076, 2017 | 37 | 2017 |
Identification of unrecognized host factors promoting HIV-1 latency Z Li, C Hajian, WC Greene PLoS pathogens 16 (12), e1009055, 2020 | 29 | 2020 |
A minor subset of super elongation complexes plays a predominant role in reversing HIV-1 latency Z Li, H Lu, Q Zhou Molecular and Cellular Biology, 2016 | 27 | 2016 |
Analysis of white spot syndrome virus envelope protein complexome by two-dimensional blue native/SDS PAGE combined with mass spectrometry Z Li, L Xu, F Li, Q Zhou, F Yang Archives of virology 156, 1125-1135, 2011 | 27 | 2011 |
Comprehensive synergy mapping links a BAF-and NSL-containing “supercomplex” to the transcriptional silencing of HIV-1 Z Li, SG Deeks, M Ott, WC Greene Cell reports 42 (9), 2023 | 1 | 2023 |