A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis L Fang, Q Zhu, M Neuenschwander, E Specker, A Wulf-Goldenberg, ... Cancer research 76 (4), 891-901, 2016 | 182 | 2016 |
Wnt/β‐catenin signalling induces MLL to create epigenetic changes in salivary gland tumours P Wend, L Fang, Q Zhu, JH Schipper, C Loddenkemper, F Kosel, ... The EMBO journal 32 (14), 1977-1989, 2013 | 118 | 2013 |
KLF4 functions as an oncogene in promoting cancer stem cell-like characteristics in osteosarcoma cells X Qi, Y Li, Y Zhang, T Xu, B Lu, L Fang, J Gao, L Yu, D Zhu, B Yang, Q He, ... Acta Pharmacologica Sinica 40 (4), 546-555, 2019 | 106 | 2019 |
A deep learning framework to predict binding preference of RNA constituents on protein surface JH Lam, Y Li, L Zhu, R Umarov, H Jiang, A Héliou, FK Sheong, T Liu, ... Nature communications 10 (1), 4941, 2019 | 94 | 2019 |
Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors P Jia, R Sheng, J Zhang, L Fang, Q He, B Yang, Y Hu European Journal of Medicinal Chemistry 44 (2), 772-784, 2009 | 82 | 2009 |
Combined Wnt/β-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome JD Holland, B Györffy, R Vogel, K Eckert, G Valenti, L Fang, P Lohneis, ... Cell reports 5 (5), 1214-1227, 2013 | 79 | 2013 |
FlsnRNA-seq: protoplasting-free full-length single-nucleus RNA profiling in plants Y Long, Z Liu, J Jia, W Mo, L Fang, D Lu, B Liu, H Zhang, W Chen, J Zhai Genome biology 22, 1-14, 2021 | 68 | 2021 |
Q39, a novel synthetic Quinoxaline 1, 4-Di-N-oxide compound with anti-cancer activity in hypoxia Q Weng, D Wang, P Guo, L Fang, Y Hu, Q He, B Yang European Journal of Pharmacology 581 (3), 262-269, 2008 | 68 | 2008 |
The evolution of posttranscriptional regulation B Schaefke, W Sun, YS Li, L Fang, W Chen Wiley Interdisciplinary Reviews: RNA 9 (5), e1485, 2018 | 63 | 2018 |
Full-length transcriptome reconstruction reveals a large diversity of RNA and protein isoforms in rat hippocampus X Wang, X You, JD Langer, J Hou, F Rupprecht, I Vlatkovic, C Quedenau, ... Nature communications 10 (1), 5009, 2019 | 56 | 2019 |
Tracing tumorigenesis in a solid tumor model at single-cell resolution SD Praktiknjo, B Obermayer, Q Zhu, L Fang, H Liu, H Quinn, M Stoeckius, ... Nature communications 11 (1), 991, 2020 | 54 | 2020 |
Akt-FOXO3a signaling axis dysregulation in human oral squamous cell carcinoma and potent efficacy of FOXO3a-targeted gene therapy L Fang, HM Wang, L Zhou, D Yu Oral oncology 47 (1), 16-21, 2011 | 44 | 2011 |
Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT H Yi, G Li, Y Long, W Liang, H Cui, B Zhang, Y Tan, Y Li, L Shen, D Deng, ... Oncogene 39 (28), 5152-5164, 2020 | 38 | 2020 |
Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization Q Weng, J Wang, J Wang, J Wang, F Sattar, Z Zhang, J Zheng, Z Xu, ... Cell Death & Disease 9 (2), 251, 2018 | 34 | 2018 |
FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells L Fang, H Wang, L Zhou, D Yu Toxicology and applied pharmacology 251 (1), 8-15, 2011 | 31 | 2011 |
GC7 enhances cisplatin sensitivity via STAT3 signaling pathway inhibition and eIF5A2 inactivation in mesenchymal phenotype oral cancer cells L Fang, L Gao, L Xie, G Xiao Oncology Reports 39 (3), 1283-1291, 2018 | 27 | 2018 |
Comparison between video-assisted and open lateral neck dissection for papillary thyroid carcinoma with lateral neck lymph node metastasis: a prospective randomized study D Zhang, L Gao, L Xie, G He, J Chen, L Fang, X Cai Journal of Laparoendoscopic & Advanced Surgical Techniques 27 (11), 1151-1157, 2017 | 27 | 2017 |
Circular RNA circRUNX1 promotes papillary thyroid cancer progression and metastasis by sponging MiR-296-3p and regulating DDHD2 expression J Chu, L Tao, T Yao, Z Chen, X Lu, L Gao, L Fang, J Chen, G He, S Shen, ... Cell Death & Disease 12 (1), 112, 2021 | 26 | 2021 |
Spatial transcriptomics reveals light-induced chlorenchyma cells involved in promoting shoot regeneration in tomato callus X Song, P Guo, K Xia, M Wang, Y Liu, L Chen, J Zhang, M Xu, N Liu, ... Proceedings of the National Academy of Sciences 120 (38), e2310163120, 2023 | 24 | 2023 |
The Wnt-driven Mll1 epigenome regulates salivary gland and head and neck cancer Q Zhu, L Fang, J Heuberger, A Kranz, J Schipper, K Scheckenbach, ... Cell Reports 26 (2), 415-428. e5, 2019 | 24 | 2019 |