Transglutaminase is a tumor cell and cancer stem cell survival factor RL Eckert, ML Fisher, D Grun, G Adhikary, W Xu, C Kerr Molecular carcinogenesis 54 (10), 947-958, 2015 | 109 | 2015 |
Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation G Adhikary, D Grun, C Kerr, S Balasubramanian, EA Rorke, M Vemuri, ... PLoS One 8 (12), e84324, 2013 | 107 | 2013 |
Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells ML Fisher, D Grun, G Adhikary, W Xu, RL Eckert Oncotarget 8 (66), 110257, 2017 | 83 | 2017 |
Transglutaminase interaction with α6/β4-integrin stimulates YAP1-dependent ΔNp63α stabilization and leads to enhanced cancer stem cell survival and tumor formation ML Fisher, C Kerr, G Adhikary, D Grun, W Xu, JW Keillor, RL Eckert Cancer research 76 (24), 7265-7276, 2016 | 81 | 2016 |
The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane ML Fisher, G Adhikary, D Grun, DM Kaetzel, RL Eckert Molecular carcinogenesis 55 (12), 2024-2036, 2016 | 71 | 2016 |
Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition ML Fisher, G Adhikary, W Xu, C Kerr, JW Keillor, RL Eckert Oncotarget 6 (24), 20525, 2015 | 71 | 2015 |
Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival ML Fisher, JW Keillor, W Xu, RL Eckert, C Kerr Molecular Cancer Research 13 (7), 1083-1094, 2015 | 68 | 2015 |
p63-related signaling at a glance ML Fisher, S Balinth, AA Mills Journal of cell science 133 (17), jcs228015, 2020 | 66 | 2020 |
Transamidase site-targeted agents alter the conformation of the transglutaminase cancer stem cell survival protein to reduce GTP binding activity and cancer stem cell survival C Kerr, H Szmacinski, ML Fisher, B Nance, JR Lakowicz, A Akbar, ... Oncogene 36 (21), 2981-2990, 2017 | 63 | 2017 |
Sulforaphane reduces YAP/∆ Np63α signaling to reduce cancer stem cell survival and tumor formation ML Fisher, N Ciavattone, D Grun, G Adhikary, RL Eckert Oncotarget 8 (43), 73407, 2017 | 40 | 2017 |
NME1 drives expansion of melanoma cells with enhanced tumor growth and metastatic properties Y Wang, MK Leonard, DE Snyder, ML Fisher, RL Eckert, DM Kaetzel Molecular Cancer Research 17 (8), 1665-1674, 2019 | 29 | 2019 |
Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation K Saha, ML Fisher, G Adhikary, D Grun, RL Eckert Carcinogenesis 38 (8), 827-836, 2017 | 27 | 2017 |
BRD4 regulates transcription factor ΔNp63α to drive a cancer stem cell phenotype in squamous cell carcinomas ML Fisher, S Balinth, Y Hwangbo, C Wu, C Ballon, JE Wilkinson, ... Cancer research 81 (24), 6246-6258, 2021 | 11 | 2021 |
EZH2 regulates a SETDB1/ΔNp63α axis via RUNX3 to drive a cancer stem cell phenotype in squamous cell carcinoma S Balinth, ML Fisher, Y Hwangbo, C Wu, C Ballon, X Sun, AA Mills Oncogene 41 (35), 4130-4144, 2022 | 10 | 2022 |
ΔNp63α in cancer: importance and therapeutic opportunities ML Fisher, S Balinth, AA Mills Trends in cell biology 33 (4), 280-292, 2023 | 9 | 2023 |
Transglutaminase 2 is a direct target gene of YAP-TAZ—response ML Fisher, G Adhikary, C Kerr, D Grun, RL Eckert Cancer research 77 (17), 4736-4736, 2017 | 8 | 2017 |
Cancer-associated fibroblasts promote cancer stemness by inducing expression of the chromatin-modifying protein CBX4 in squamous cell carcinoma ML Fisher, S Balinth, Y Hwangbo, C Wu, C Ballon, GL Goldberg, AA Mills Carcinogenesis 44 (6), 485-496, 2023 | 1 | 2023 |
Methods of treating resistant cancers RL Eckert, M Fisher, D Grun, G Adhikary, W Xu US Patent 11,246,856, 2022 | | 2022 |
TG2 inhibitor piperazine compounds and uses thereof JW Keillor, A Akbar, RL Eckert, M Fisher, GVW JOHNSON US Patent 10,894,777, 2021 | | 2021 |