Endothelial cell heterogeneity of blood‐brain barrier gene expression along the cerebral microvasculature JA Macdonald, N Murugesan, JS Pachter Journal of neuroscience research 88 (7), 1457-1474, 2010 | 110 | 2010 |
Plasma kallikrein-kinin system as a VEGF-independent mediator of diabetic macular edema T Kita, AC Clermont, N Murugesan, Q Zhou, K Fujisawa, T Ishibashi, ... Diabetes 64 (10), 3588-3599, 2015 | 82 | 2015 |
Brain regional angiogenic potential at the neurovascular unit during normal aging N Murugesan, TG Demarest, JA Madri, JS Pachter Neurobiology of aging 33 (5), 1004. e1-1004. e16, 2012 | 82 | 2012 |
Active induction of experimental autoimmune encephalomyelitis by MOG 35-55 peptide immunization is associated with differential responses in separate compartments of the … N Murugesan, D Paul, Y Lemire, B Shrestha, S Ge, JS Pachter Fluids and Barriers of the CNS 9 (1), 15, 2012 | 53 | 2012 |
Analysis of mouse brain microvascular endothelium using immuno‐laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform‐mass spectrometry … Q Lu, N Murugesan, JA Macdonald, SL Wu, JS Pachter, WS Hancock Electrophoresis 29 (12), 2689-2695, 2008 | 47 | 2008 |
Thrombosis and hemorrhage in diabetic retinopathy: a perspective from an inflammatory standpoint N Murugesan, T Üstunkaya, EP Feener Seminars in thrombosis and hemostasis 41 (06), 659-664, 2015 | 39 | 2015 |
Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and Thickening A Clermont, N Murugesan, Q Zhou, T Kita, PA Robson, LJ Rushbrooke, ... Investigative ophthalmology & visual science 57 (6), 2390-2399, 2016 | 34 | 2016 |
Astrocyte-and endothelial-targeted CCL2 conditional knockout mice: critical tools for studying the pathogenesis of neuroinflammation S Ge, N Murugesan, JS Pachter Journal of molecular neuroscience 39 (1-2), 269, 2009 | 32 | 2009 |
Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood–brain barrier gene expression in situ JA Macdonald, N Murugesan, JS Pachter Journal of neuroscience methods 174 (2), 219-226, 2008 | 32 | 2008 |
Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan® low density array TG Demarest, N Murugesan, B Shrestha, JS Pachter Journal of neuroscience methods 206 (2), 200-204, 2012 | 24 | 2012 |
Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics N Murugesan, JA Macdonald, Q Lu, SL Wu, WS Hancock, JS Pachter The Blood-Brain and Other Neural Barriers, 297-311, 2011 | 24 | 2011 |
Retinal proteome associated with bradykinin-induced edema N Murugesan, W Fickweiler, AC Clermont, Q Zhou, EP Feener Experimental eye research 186, 107744, 2019 | 7 | 2019 |
KVD900 as a Single Dose, Rapid, Oral Plasma Kallikrein Inhibitor for the On-Demand Treatment of Hereditary Angioedema Attacks: Pharmacokinetic and Pharmacodynamic results from … SL Hampton, GM De Donatis, NI Murugesan, LJ Rushbrooke, L Li, ... Journal of Allergy and Clinical Immunology 143 (2), AB39, 2019 | 6 | 2019 |
Probing the CNS microvascular endothelium by immune-guided laser-capture microdissection coupled to quantitative RT-PCR N Murugesan, J Macdonald, S Ge, JS Pachter Laser Capture Microdissection, 385-394, 2011 | 6 | 2011 |
A novel oral plasma kallikrein (PKal) inhibitor KV123833 blocks VEGF-mediated retinal vascular hyperpermeability in a murine model of retinal edema (# 3464) N Murugesan, AC Clermont, LJ Rushbrooke, PA Robson, ... | 5 | 2018 |
Novel oral plasma kallikrein (PKa) inhibitors KV998052 and KV998054 ameliorate VEGF-induced retinal thickening in a murine model of retinal edema N Murugesan, AC Clermont, SJ Pethen, L Li, EJ Duckworth, SL Hampton, ... Investigative Ophthalmology & Visual Science 60 (9), 2596-2596, 2019 | 1 | 2019 |
Vascular endothelial growth factor (VEGF) mediates electroretinogram (ERG) dysfunction in mice through plasma kallikrein and nitric oxide AC Clermont, F Simao, N Murugesan, P Huang, LP Aiello, EP Feener Investigative Ophthalmology & Visual Science 59 (9), 3463-3463, 2018 | 1 | 2018 |
KVD900 protects high molecular weight kininogen (HK) from ex vivo plasma kallikrein mediated cleavage in plasma from patients with hereditary angioedema (HAE): Results from a … EP Feener, N Murugesan, PA Robson, L Li, LJ Rushbrooke, R Thoonen, ... EAACI, 2018 | 1 | 2018 |
Plasma kallikrein (PKal) deficiency ameliorates the effects of vascular endothelial growth factor (VEGF) on retinal hyperpermeability and edema. AC Clermont, Q Zhou, N Murugesan, W Fickweiler, EP Feener Investigative Ophthalmology & Visual Science 55 (13), 594-594, 2014 | 1 | 2014 |
Endothelial Cell Heterogeneity of Blood–Brain Barrier Gene Expression: Analysis by LCM/qRT-PCR T Demarest, N Murugesan, JA Macdonald, JS Pachter Expression Profiling in Neuroscience, 63-75, 2012 | 1 | 2012 |