关注
Nivetha Murugesan
Nivetha Murugesan
Principal Scientist, KalVista Pharmaceuticals
在 kalvista.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Endothelial cell heterogeneity of blood‐brain barrier gene expression along the cerebral microvasculature
JA Macdonald, N Murugesan, JS Pachter
Journal of neuroscience research 88 (7), 1457-1474, 2010
1102010
Plasma kallikrein-kinin system as a VEGF-independent mediator of diabetic macular edema
T Kita, AC Clermont, N Murugesan, Q Zhou, K Fujisawa, T Ishibashi, ...
Diabetes 64 (10), 3588-3599, 2015
822015
Brain regional angiogenic potential at the neurovascular unit during normal aging
N Murugesan, TG Demarest, JA Madri, JS Pachter
Neurobiology of aging 33 (5), 1004. e1-1004. e16, 2012
822012
Active induction of experimental autoimmune encephalomyelitis by MOG 35-55 peptide immunization is associated with differential responses in separate compartments of the …
N Murugesan, D Paul, Y Lemire, B Shrestha, S Ge, JS Pachter
Fluids and Barriers of the CNS 9 (1), 15, 2012
532012
Analysis of mouse brain microvascular endothelium using immuno‐laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform‐mass spectrometry …
Q Lu, N Murugesan, JA Macdonald, SL Wu, JS Pachter, WS Hancock
Electrophoresis 29 (12), 2689-2695, 2008
472008
Thrombosis and hemorrhage in diabetic retinopathy: a perspective from an inflammatory standpoint
N Murugesan, T Üstunkaya, EP Feener
Seminars in thrombosis and hemostasis 41 (06), 659-664, 2015
392015
Plasma Kallikrein Mediates Vascular Endothelial Growth Factor–Induced Retinal Dysfunction and Thickening
A Clermont, N Murugesan, Q Zhou, T Kita, PA Robson, LJ Rushbrooke, ...
Investigative ophthalmology & visual science 57 (6), 2390-2399, 2016
342016
Astrocyte-and endothelial-targeted CCL2 conditional knockout mice: critical tools for studying the pathogenesis of neuroinflammation
S Ge, N Murugesan, JS Pachter
Journal of molecular neuroscience 39 (1-2), 269, 2009
322009
Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood–brain barrier gene expression in situ
JA Macdonald, N Murugesan, JS Pachter
Journal of neuroscience methods 174 (2), 219-226, 2008
322008
Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan® low density array
TG Demarest, N Murugesan, B Shrestha, JS Pachter
Journal of neuroscience methods 206 (2), 200-204, 2012
242012
Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics
N Murugesan, JA Macdonald, Q Lu, SL Wu, WS Hancock, JS Pachter
The Blood-Brain and Other Neural Barriers, 297-311, 2011
242011
Retinal proteome associated with bradykinin-induced edema
N Murugesan, W Fickweiler, AC Clermont, Q Zhou, EP Feener
Experimental eye research 186, 107744, 2019
72019
KVD900 as a Single Dose, Rapid, Oral Plasma Kallikrein Inhibitor for the On-Demand Treatment of Hereditary Angioedema Attacks: Pharmacokinetic and Pharmacodynamic results from …
SL Hampton, GM De Donatis, NI Murugesan, LJ Rushbrooke, L Li, ...
Journal of Allergy and Clinical Immunology 143 (2), AB39, 2019
62019
Probing the CNS microvascular endothelium by immune-guided laser-capture microdissection coupled to quantitative RT-PCR
N Murugesan, J Macdonald, S Ge, JS Pachter
Laser Capture Microdissection, 385-394, 2011
62011
A novel oral plasma kallikrein (PKal) inhibitor KV123833 blocks VEGF-mediated retinal vascular hyperpermeability in a murine model of retinal edema (# 3464)
N Murugesan, AC Clermont, LJ Rushbrooke, PA Robson, ...
52018
Novel oral plasma kallikrein (PKa) inhibitors KV998052 and KV998054 ameliorate VEGF-induced retinal thickening in a murine model of retinal edema
N Murugesan, AC Clermont, SJ Pethen, L Li, EJ Duckworth, SL Hampton, ...
Investigative Ophthalmology & Visual Science 60 (9), 2596-2596, 2019
12019
Vascular endothelial growth factor (VEGF) mediates electroretinogram (ERG) dysfunction in mice through plasma kallikrein and nitric oxide
AC Clermont, F Simao, N Murugesan, P Huang, LP Aiello, EP Feener
Investigative Ophthalmology & Visual Science 59 (9), 3463-3463, 2018
12018
KVD900 protects high molecular weight kininogen (HK) from ex vivo plasma kallikrein mediated cleavage in plasma from patients with hereditary angioedema (HAE): Results from a …
EP Feener, N Murugesan, PA Robson, L Li, LJ Rushbrooke, R Thoonen, ...
EAACI, 2018
12018
Plasma kallikrein (PKal) deficiency ameliorates the effects of vascular endothelial growth factor (VEGF) on retinal hyperpermeability and edema.
AC Clermont, Q Zhou, N Murugesan, W Fickweiler, EP Feener
Investigative Ophthalmology & Visual Science 55 (13), 594-594, 2014
12014
Endothelial Cell Heterogeneity of Blood–Brain Barrier Gene Expression: Analysis by LCM/qRT-PCR
T Demarest, N Murugesan, JA Macdonald, JS Pachter
Expression Profiling in Neuroscience, 63-75, 2012
12012
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