Regulation of LSD1 histone demethylase activity by its associated factors YJ Shi, C Matson, F Lan, S Iwase, T Baba, Y Shi Molecular cell 19 (6), 857-864, 2005 | 1044 | 2005 |
A histone H3 lysine 27 demethylase regulates animal posterior development F Lan, PE Bayliss, JL Rinn, JR Whetstine, JK Wang, S Chen, S Iwase, ... Nature 449 (7163), 689-694, 2007 | 916 | 2007 |
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases S Iwase, F Lan, P Bayliss, L de la Torre-Ubieta, M Huarte, HH Qi, ... Cell 128 (6), 1077-1088, 2007 | 774 | 2007 |
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome S Iwase, B Xiang, S Ghosh, T Ren, PW Lewis, JC Cochrane, CD Allis, ... Nature structural & molecular biology 18 (7), 769-776, 2011 | 296 | 2011 |
Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders CN Vallianatos, S Iwase Epigenomics 7 (3), 503-519, 2015 | 178 | 2015 |
Epigenetic etiology of intellectual disability S Iwase, NG Bérubé, Z Zhou, NN Kasri, E Battaglioli, M Scandaglia, ... Journal of Neuroscience 37 (45), 10773-10782, 2017 | 145 | 2017 |
Identification and characterization of two novel JARID1C mutations: suggestion of an emerging genotype–phenotype correlation S Rujirabanjerd, J Nelson, PS Tarpey, A Hackett, S Edkins, FL Raymond, ... European Journal of Human Genetics 18 (3), 330-335, 2010 | 139* | 2010 |
A mouse model of X-linked intellectual disability associated with impaired removal of histone methylation S Iwase, E Brookes, S Agarwal, AI Badeaux, H Ito, CN Vallianatos, ... Cell reports 14 (5), 1000-1009, 2016 | 127 | 2016 |
Loss of Kdm5c causes spurious transcription and prevents the fine-tuning of activity-regulated enhancers in neurons M Scandaglia, JP Lopez-Atalaya, A Medrano-Fernandez, ... Cell reports 21 (1), 47-59, 2017 | 102 | 2017 |
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice S Cui, KC Lim, L Shi, M Lee, N Jearawiriyapaisarn, G Myers, A Campbell, ... Blood, The Journal of the American Society of Hematology 126 (3), 386-396, 2015 | 95 | 2015 |
Functional analysis of SLC39A8 mutations and their implications for manganese deficiency and mitochondrial disorders EK Choi, TT Nguyen, N Gupta, S Iwase, YA Seo Scientific reports 8 (1), 3163, 2018 | 88 | 2018 |
Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders RS Porter, F Jaamour, S Iwase Molecular and Cellular Neuroscience 87, 35-45, 2018 | 79 | 2018 |
X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity JC Link, CB Wiese, X Chen, R Avetisyan, E Ronquillo, F Ma, X Guo, J Yao, ... The Journal of clinical investigation 130 (11), 5688-5702, 2020 | 77 | 2020 |
Synthesis, processing, and subcellular localization of mouse ADAM3 during spermatogenesis and epididymal sperm transport E Kim, H Nishimura, S Iwase, K Yamagata, S Kashiwabara, T Baba Journal of Reproduction and Development 50 (5), 571-578, 2004 | 77 | 2004 |
Characterization of BHC80 in BRAF–HDAC complex, involved in neuron-specific gene repression S Iwase, A Januma, K Miyamoto, N Shono, A Honda, J Yanagisawa, ... Biochemical and biophysical research communications 322 (2), 601-608, 2004 | 65 | 2004 |
An atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic … JDJ Labonne, KH Lee, S Iwase, IK Kong, MP Diamond, LC Layman, ... Human genetics 135, 757-771, 2016 | 60 | 2016 |
Altered gene-regulatory function of KDM5C by a novel mutation associated with autism and intellectual disability CN Vallianatos, C Farrehi, MJ Friez, M Burmeister, CE Keegan, S Iwase Frontiers in molecular neuroscience 11, 104, 2018 | 57 | 2018 |
Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice Y Sogawa, H Nagasu, S Iwase, C Ihoriya, S Itano, A Uchida, K Kidokoro, ... Scientific Reports 7 (1), 8801, 2017 | 48 | 2017 |
Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation CN Vallianatos, B Raines, RS Porter, KM Bonefas, MC Wu, PM Garay, ... Communications biology 3 (1), 278, 2020 | 46 | 2020 |
Impact of dietary manganese on experimental colitis in mice EK Choi, L Aring, NK Das, S Solanki, N Inohara, S Iwase, LC Samuelson, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 45 | 2020 |