The emerging role of H3K9me3 as a potential therapeutic target in acute myeloid leukemia L Monaghan, ME Massett, RP Bunschoten, A Hoose, PA Pirvan, ... Frontiers in oncology 9, 705, 2019 | 70 | 2019 |
A molecular signature for delayed graft function D McGuinness, S Mohammed, L Monaghan, PA Wilson, DB Kingsmore, ... Aging Cell 17 (5), e12825, 2018 | 31 | 2018 |
A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival ME Massett, L Monaghan, S Patterson, N Mannion, RP Bunschoten, ... Cell death & disease 12 (6), 573, 2021 | 27 | 2021 |
The histone demethylase KDM4A is required to sustain H3K9me3/H3K27me3 epigenetic states and oncogenesis in MLL-AF9 acute myeloid leukemia ME Massett, N Mannion, L Monaghan, J Bittencourt-Silvestre, S Marmiroli, ... Blood 132, 3879, 2018 | 2 | 2018 |
P433: PHARMACOLOGICAL DUAL INHIBITION OF PARP AND TIP60 AS A PROSPECTIVE THERAPEUTIC REGIMEN INDUCES SYNERGISTIC AML CELL DEATH TJ Park, H Wheadon, L Monaghan, X Huang, H Jorgensen HemaSphere 7 (S3), e20033ee, 2023 | | 2023 |
Synergistic Leukaemia Cell Death Induced with PARP and TiP60 Inhibitors Is a Prospective Therapeutic Strategy for AML TJ Park, L Monaghan, M Copland, X Huang, H Wheadon, HG Jørgensen Blood 140 (Supplement 1), 13001-13002, 2022 | | 2022 |
Pharmacological targeting of KDM4A as a potential therapeutic strategy in AML L Monaghan University of Glasgow, 2021 | | 2021 |
Combination therapies targeting DNA damage signalling as a therapeutic strategy in acute myeloid leukaemia L Monaghan, RP Bunschoten, S Gannon, A Hoose, PA Pirvan, T Park, ... BRITISH JOURNAL OF HAEMATOLOGY 189, 53-54, 2020 | | 2020 |
Efficient Elimination of Acute Myeloid Leukemia Cells through Inhibition of KDM4A in Combination with PARP Inhibition L Monaghan, ME Massett, RP Bunschoten, PA Pirvan, A Hoose, T Park, ... Blood 134, 3756, 2019 | | 2019 |
Identification of signalling pathways regulated by KDM4A in MLL-AF9 AML via a novel kinase activity screen S Patterson, L Monaghan, YC Hsieh, J Hay, A Michie, X Huang BRITISH JOURNAL OF HAEMATOLOGY 185, 38-39, 2019 | | 2019 |
DELAYED GRAFT FUNCTION OUTCOME IS ASSOCIATED WITH SENESCENCE PROGRAMMES D Mcguinness, S Mohammed, L Monaghan, DB Kingsmore, O Shapter, ... TRANSPLANT INTERNATIONAL 30, 18-18, 2017 | | 2017 |
Senescence-Associated Microrna Expression In Serum Exsosomes And Vastus Lateralis Muscle Samples From COPD Patients With Low And Normal Fat Free Mass Index R Lakhdar, D McGuinness, L Monaghan, E Drost, P Sheils, B MacNee, ... B58. BIG AND BIGGER (DATA): OMICS AND BIOMARKERS OF COPD AND OTHER CHRONIC …, 2016 | | 2016 |
B58 BIG AND BIGGER (DATA): OMICS AND BIOMARKERS OF COPD AND OTHER CHRONIC LUNG DISEASES: Senescence-Associated Microrna Expression In Serum Exsosomes And Vastus Lateralis … R Lakhdar, D McGuinness, L Monaghan, E Drost, P Sheils, B MacNee, ... American Journal of Respiratory and Critical Care Medicine 193, 1, 2016 | | 2016 |