Downstream processing of lentiviral vectors: releasing bottlenecks V Bandeira, C Peixoto, AF Rodrigues, PE Cruz, PM Alves, AS Coroadinha, ... Human Gene Therapy, Part B: Methods 23 (4), 255-263, 2012 | 104 | 2012 |
Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology AF Rodrigues, HR Soares, MR Guerreiro, PM Alves, AS Coroadinha Biotechnology journal 10 (9), 1329-1344, 2015 | 87 | 2015 |
LentiPro26: novel stable cell lines for constitutive lentiviral vector production HA Tomás, AF Rodrigues, MJT Carrondo, AS Coroadinha Scientific reports 8 (1), 5271, 2018 | 57 | 2018 |
Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer M Carmo, A Alves, AF Rodrigues, AS Coroadinha, MJT Carrondo, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2009 | 49 | 2009 |
Production of retroviral and lentiviral gene therapy vectors: challenges in the manufacturing of lipid enveloped virus AF Rodrigues, PM Alves, AS Coroadinha Viral gene therapy, 15-40, 2011 | 45 | 2011 |
Robust expansion of human pluripotent stem cells: integration of bioprocess design with transcriptomic and metabolomic characterization MM Silva, AF Rodrigues, C Correia, MFQ Sousa, C Brito, AS Coroadinha, ... Stem cells translational medicine 4 (7), 731-742, 2015 | 44 | 2015 |
MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1 N Schmolka, PH Papotto, PV Romero, T Amado, FJ Enguita, A Amorim, ... Science immunology 3 (23), eaao1392, 2018 | 43 | 2018 |
Retroviral vector production under serum deprivation: The role of lipids AF Rodrigues, M Carmo, PM Alves, AS Coroadinha Biotechnology and bioengineering 104 (6), 1171-1181, 2009 | 39 | 2009 |
Metabolic pathways recruited in the production of a recombinant enveloped virus: Mining targets for process and cell engineering AF Rodrigues, AS Formas-Oliveira, VS Bandeira, PM Alves, WS Hu, ... Metabolic Engineering 20, 131-145, 2013 | 37 | 2013 |
Lentiviral gene therapy vectors: challenges and future directions HA Tomás, AF Rodrigues, PM Alves, AS Coroadinha Gene therapy-tools and potential applications, 2013 | 37 | 2013 |
Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells AF Rodrigues, MJT Carrondo, PM Alves, AS Coroadinha Trends in biotechnology 32 (12), 602-607, 2014 | 32 | 2014 |
Year-long rhinovirus infection is influenced by atmospheric conditions, outdoor air virus presence, and immune system-related genetic polymorphisms AF Rodrigues, AM Santos, AM Ferreira, R Marino, ME Barreira, ... Food and environmental virology 11 (4), 340-349, 2019 | 25 | 2019 |
Improved GaLV-TR glycoproteins to pseudotype lentiviral vectors: impact of viral protease activity in the production of LV pseudotypes HA Tomás, DA Mestre, AF Rodrigues, MR Guerreiro, MJT Carrondo, ... Molecular Therapy-Methods & Clinical Development 15, 1-8, 2019 | 21 | 2019 |
Impact of E1 and Cre on adenovirus vector amplification: developing MDCK CAV-2-E1 and E1-Cre transcomplementing cell lines P Fernandes, VM Santiago, AF Rodrigues, H Tomas, EJ Kremer, ... PLoS One 8 (4), e60342, 2013 | 20 | 2013 |
Tetraspanins displayed in retrovirus-derived virus-like particles and their immunogenicity HR Soares, R Castro, HA Tomás, AF Rodrigues, P Gomes-Alves, B Bellier, ... Vaccine 34 (13), 1634-1641, 2016 | 17 | 2016 |
Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down‐regulation of HIF1 and PDK AF Rodrigues, MR Guerreiro, AS Formas‐Oliveira, P Fernandes, ... Biotechnology and bioengineering 113 (1), 150-162, 2016 | 16 | 2016 |
Overexpression of ER protein processing and apoptosis regulator genes in human embryonic kidney 293 cells improves gene therapy vectors production AS Formas‐Oliveira, JS Basílio, AF Rodrigues, AS Coroadinha Biotechnology Journal 15 (9), 1900562, 2020 | 15 | 2020 |
Single-step cloning-screening method: a new tool for developing and studying high-titer viral vector producer cells AF Rodrigues, AS Formas-Oliveira, MR Guerreiro, HA Tomás, PM Alves, ... Gene Therapy 22 (9), 685-695, 2015 | 12 | 2015 |
Adaptation of retrovirus producer cells to serum deprivation: Implications in lipid biosynthesis and vector production AF Rodrigues, AI Amaral, V Verissimo, PM Alves, AS Coroadinha Biotechnology and bioengineering 109 (5), 1269-1279, 2012 | 12 | 2012 |
Down‐regulation of CD81 tetraspanin in human cells producing retroviral‐based particles: Tailoring vector composition AF Rodrigues, MR Guerreiro, VM Santiago, C Dalba, D Klatzmann, ... Biotechnology and bioengineering 108 (11), 2623-2633, 2011 | 12 | 2011 |