Obesity‐related leptin regulates Alzheimer's Aβ DC Fewlass, K Noboa, FX Pi‐Sunyer, JM Johnston, SD Yan, N Tezapsidis The FASEB journal 18 (15), 1870-1878, 2004 | 371 | 2004 |
Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease SJ Greco, KJ Bryan, S Sarkar, X Zhu, MA Smith, JW Ashford, JM Johnston, ... Journal of Alzheimer's Disease 19 (4), 1155-1167, 2010 | 262 | 2010 |
Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells SJ Greco, S Sarkar, JM Johnston, N Tezapsidis Biochemical and biophysical research communications 380 (1), 98-104, 2009 | 219 | 2009 |
Leptin reduces Alzheimer’s disease-related tau phosphorylation in neuronal cells SJ Greco, S Sarkar, JM Johnston, X Zhu, B Su, G Casadesus, JW Ashford, ... Biochemical and biophysical research communications 376 (3), 536-541, 2008 | 163 | 2008 |
Leptin: a novel therapeutic strategy for Alzheimer's disease N Tezapsidis, JM Johnston, MA Smith, JW Ashford, G Casadesus, ... Journal of Alzheimer's Disease 16 (4), 731-740, 2009 | 157 | 2009 |
Leptin inhibits glycogen synthase kinase-3β to prevent tau phosphorylation in neuronal cells SJ Greco, S Sarkar, G Casadesus, X Zhu, MA Smith, JW Ashford, ... Neuroscience letters 455 (3), 191-194, 2009 | 144 | 2009 |
Mesencephalic type 1 astrocytes rescue dopaminergic neurons from death induced by serum deprivation T Takeshima, JM Johnston, JW Commissiong Journal of Neuroscience 14 (8), 4769-4779, 1994 | 144 | 1994 |
Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor JPM Finberg, T Takeshima, JM Johnston, JW Commissiong Neuroreport 9 (4), 703-707, 1998 | 133 | 1998 |
Dopamine, the dopamine D2 receptor and pituitary tumours. DF Wood, JM Johnston, DG Johnston Clinical endocrinology 35 (6), 455-466, 1991 | 118 | 1991 |
Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains GA Elder, N Tezapsidis, J Carter, J Shioi, C Bouras, HC Li, JM Johnston, ... Journal of neuroscience research 45 (3), 308-320, 1996 | 113 | 1996 |
Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons SJ Greco, A Hamzelou, JM Johnston, MA Smith, JW Ashford, ... Biochemical and biophysical research communications 414 (1), 170-174, 2011 | 112 | 2011 |
Standardized methods to bioassay neurotrophic factors for dopaminergic neurons T Takeshima, K Shimoda, JM Johnston, JW Commissiong Journal of neuroscience methods 67 (1), 27-41, 1996 | 67 | 1996 |
Low Plasma Leptin in Cognitively Impaired ADNI Subjects: Gender Differences and Diagnostic and Therapeutic Potential NT Jane M. Johnston, William T. Hu, David W. Fardo, Steven J. Greco, George ... Current Alzheimer Research 11 (2), 165-178, 2014 | 64 | 2014 |
Hormone-induced calcium oscillations depend on cross-coupling with inositol 1, 4, 5-trisphosphate oscillations LD Gaspers, PJ Bartlett, A Politi, P Burnett, W Metzger, J Johnston, ... Cell reports 9 (4), 1209-1218, 2014 | 57 | 2014 |
Repositioning leptin as a therapy for Alzheimer's disease JM Johnston, SJ Greco, A Hamzelou, JW Ashford, N Tezapsidis Therapy 8 (5), 481, 2011 | 43 | 2011 |
Oligodendrocyte-type-2 astrocyte (O-2A) progenitors increase the survival of rat mesencephalic, dopaminergic neurons from death induced by serum deprivation T Takeshima, JM Johnston, JW Commissiong Neuroscience letters 166 (2), 178-182, 1994 | 39 | 1994 |
Altered binding of mutated presenilin with cytoskeleton-interacting proteins AA Johnsingh, JM Johnston, G Merz, J Xu, L Kotula, JS Jacobsen, ... FEBS letters 465 (1), 53-58, 2000 | 34 | 2000 |
An immortalized, type-1 astrocyte of mescencephalic origin source of a dopaminergic neurotrophic factor DM Panchision, PA Martin-DeLeon, T Takeshima, JM Johnston, ... Journal of molecular neuroscience 11, 209-221, 1998 | 32 | 1998 |
Calcium oscillations in type-1 astrocytes, the effect of a presenilin 1 (PS1) mutation JM Johnston, P Burnett, AP Thomas, N Tezapsidis Neuroscience letters 395 (2), 159-164, 2006 | 30 | 2006 |
Production of dopaminergic neurons for cell therapy in the treatment of Parkinson's disease AE Peaire, T Takeshima, JM Johnston, K Isoe, K Nakashima, ... Journal of neuroscience methods 124 (1), 61-74, 2003 | 20 | 2003 |