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Mostafa El-Miligy
Mostafa El-Miligy
Professor of pharmaceutical chemistry, Faculty of Pharmacy, Alexandria University
在 alexu.edu.eg 的电子邮件经过验证
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引用次数
引用次数
年份
Synthesis of novel benzofuran and related benzimidazole derivatives for evaluation ofin vitro anti-HIV-1, anticancer and antimicrobial activities
SM Rida, SAM El-Hawash, HTY Fahmy, AA Hazzaa, MMM El-Meligy
Archives of pharmacal research 29, 826-833, 2006
2112006
New heterocyclic hybrids of pyrazole and its bioisosteres: Design, synthesis and biological evaluation as dual acting antimalarial-antileishmanial agents
AA Bekhit, AMM Hassan, HA Abd El Razik, MMM El-Miligy, EJ El-Agroudy, ...
European journal of medicinal chemistry 94, 30-44, 2015
1492015
Design, synthesis and docking study of pyridine and thieno [2, 3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors
ME Abdelaziz, MMM El-Miligy, SM Fahmy, MA Mahran, AA Hazzaa
Bioorganic chemistry 80, 674-692, 2018
662018
New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study
MMM El-Miligy, AA Hazzaa, H El-Messmary, RA Nassra, SAM El-Hawash
Bioorganic chemistry 72, 102-115, 2017
602017
Synthesis andin vitro evaluation of some novel benzofuran derivatives as potential anti-HIV-1, anticancer, and antimicrobial agents
SM Rida, SAM El-Hawash, HTY Fahmy, AA Hazza, MMM El-Meligy
Archives of pharmacal research 29, 16-25, 2006
512006
Design, synthesis, biological evaluation and docking studies of new 3-(4, 5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15 …
HS ElBordiny, MM El-Miligy, SE Kassab, H Daabees, WAM Ali, ...
European journal of medicinal chemistry 145, 594-605, 2018
472018
Design and synthesis of some β-carboline derivatives as multi-target anticancer agents
MA Abdelsalam, OM AboulWafa, ESAM Badawey, MS El-Shoukrofy, ...
Future Medicinal Chemistry 10 (24), 2791-2814, 2018
272018
Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis
MMM El-Miligy, HA Abd El Razik, MM Abu-Serie
Future Medicinal Chemistry 9 (15), 1709-1729, 2017
222017
Design, Synthesis, Anticancer Screening, Docking Studies and In Silico ADME Prediction of Some β-Carboline Derivatives
MA Abdelsalam, OM AboulWafa, ESA M Badawey, MS El-Shoukrofy, ...
Future Medicinal Chemistry 10 (10), 1159-1175, 2018
162018
Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes
MMM El-Miligy, AK Al-Kubeisi, SR El-Zemity, RA Nassra, MM Abu-Serie, ...
Bioorganic Chemistry 115, 105171, 2021
142021
Towards safer anti-inflammatory therapy: synthesis of new thymol–pyrazole hybrids as dual COX-2/5-LOX inhibitors
MMM El-Miligy, AK Al-Kubeisi, MG Bekhit, SR El-Zemity, RA Nassra, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 294-308, 2023
122023
New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study
MMM El-Miligy, AA Hazzaa, H El-Messmary, RA Nassra, SAM El-Hawash
Future Medicinal Chemistry 9 (5), 443-468, 2017
122017
Synthesis of Thymol Derivatives as Potential Non-Irritant Antimicrobial and Insecticidal Agents
MMM El-Miligy, AA Hazzaa, SR El-Zemity, AK Al-Kubeisi
Current Bioactive Compounds 13, 2017
102017
Dual inhibitors of hepatitis C virus and hepatocellular carcinoma: design, synthesis and docking studies
MMM El-Miligy, SM Rida, FA Ashour, MH Badr, EM El-Bassiony, ...
Future Science OA 4 (1), FSO252, 2018
72018
Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities
MMM El-Miligy, ME Abdelaziz, SM Fahmy, TM Ibrahim, MM Abu-Serie, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2152810, 2023
62023
Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme
NH El-Dershaby, SA El-Hawash, SE Kassab, HG Dabees, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1737-1751, 2022
62022
Rational design and synthesis of new selective COX-2 inhibitors with In Vivo PGE2-lowering activity by tethering benzenesulfonamide and 1, 2, 3-triazole pharmacophores to some …
NH El-Dershaby, SA El-Hawash, SE Kassab, HG Daabees, ...
Pharmaceuticals 15 (10), 1165, 2022
32022
Design, Synthesis, Biological Evaluation and Docking Studies of New Derivatives as Potent Antioxidants and 15-Lipoxygenase Inhibitors
HS ElBordiny, MM El-Miligy, SE Kassab, H Daabees, AW Mohamed, ...
Eur. J. Med. Chem 145, 594-605, 2018
22018
Discovery of new thymol-3,4-disubstituted thiazole hybrids as dual COX-2/5-LOX inhibitors with in vivo proof
MMM El-Miligy, AK Al-Kubeisi, RA Nassra, SR El-Zemity, AA Hazzaa
Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2309171, 2024
2024
Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated …
ME Abdelaziz, MMM El-Miligy, SM Fahmy, MM Abu-Serie, AA Hazzaa, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2304044, 2024
2024
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