Synthesis of novel benzofuran and related benzimidazole derivatives for evaluation ofin vitro anti-HIV-1, anticancer and antimicrobial activities SM Rida, SAM El-Hawash, HTY Fahmy, AA Hazzaa, MMM El-Meligy Archives of pharmacal research 29, 826-833, 2006 | 211 | 2006 |
New heterocyclic hybrids of pyrazole and its bioisosteres: Design, synthesis and biological evaluation as dual acting antimalarial-antileishmanial agents AA Bekhit, AMM Hassan, HA Abd El Razik, MMM El-Miligy, EJ El-Agroudy, ... European journal of medicinal chemistry 94, 30-44, 2015 | 149 | 2015 |
Design, synthesis and docking study of pyridine and thieno [2, 3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors ME Abdelaziz, MMM El-Miligy, SM Fahmy, MA Mahran, AA Hazzaa Bioorganic chemistry 80, 674-692, 2018 | 66 | 2018 |
New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study MMM El-Miligy, AA Hazzaa, H El-Messmary, RA Nassra, SAM El-Hawash Bioorganic chemistry 72, 102-115, 2017 | 60 | 2017 |
Synthesis andin vitro evaluation of some novel benzofuran derivatives as potential anti-HIV-1, anticancer, and antimicrobial agents SM Rida, SAM El-Hawash, HTY Fahmy, AA Hazza, MMM El-Meligy Archives of pharmacal research 29, 16-25, 2006 | 51 | 2006 |
Design, synthesis, biological evaluation and docking studies of new 3-(4, 5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15 … HS ElBordiny, MM El-Miligy, SE Kassab, H Daabees, WAM Ali, ... European journal of medicinal chemistry 145, 594-605, 2018 | 47 | 2018 |
Design and synthesis of some β-carboline derivatives as multi-target anticancer agents MA Abdelsalam, OM AboulWafa, ESAM Badawey, MS El-Shoukrofy, ... Future Medicinal Chemistry 10 (24), 2791-2814, 2018 | 27 | 2018 |
Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis MMM El-Miligy, HA Abd El Razik, MM Abu-Serie Future Medicinal Chemistry 9 (15), 1709-1729, 2017 | 22 | 2017 |
Design, Synthesis, Anticancer Screening, Docking Studies and In Silico ADME Prediction of Some β-Carboline Derivatives MA Abdelsalam, OM AboulWafa, ESA M Badawey, MS El-Shoukrofy, ... Future Medicinal Chemistry 10 (10), 1159-1175, 2018 | 16 | 2018 |
Discovery of small molecule acting as multitarget inhibitor of colorectal cancer by simultaneous blocking of the key COX-2, 5-LOX and PIM-1 kinase enzymes MMM El-Miligy, AK Al-Kubeisi, SR El-Zemity, RA Nassra, MM Abu-Serie, ... Bioorganic Chemistry 115, 105171, 2021 | 14 | 2021 |
Towards safer anti-inflammatory therapy: synthesis of new thymol–pyrazole hybrids as dual COX-2/5-LOX inhibitors MMM El-Miligy, AK Al-Kubeisi, MG Bekhit, SR El-Zemity, RA Nassra, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 294-308, 2023 | 12 | 2023 |
New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study MMM El-Miligy, AA Hazzaa, H El-Messmary, RA Nassra, SAM El-Hawash Future Medicinal Chemistry 9 (5), 443-468, 2017 | 12 | 2017 |
Synthesis of Thymol Derivatives as Potential Non-Irritant Antimicrobial and Insecticidal Agents MMM El-Miligy, AA Hazzaa, SR El-Zemity, AK Al-Kubeisi Current Bioactive Compounds 13, 2017 | 10 | 2017 |
Dual inhibitors of hepatitis C virus and hepatocellular carcinoma: design, synthesis and docking studies MMM El-Miligy, SM Rida, FA Ashour, MH Badr, EM El-Bassiony, ... Future Science OA 4 (1), FSO252, 2018 | 7 | 2018 |
Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities MMM El-Miligy, ME Abdelaziz, SM Fahmy, TM Ibrahim, MM Abu-Serie, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2152810, 2023 | 6 | 2023 |
Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme NH El-Dershaby, SA El-Hawash, SE Kassab, HG Dabees, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1737-1751, 2022 | 6 | 2022 |
Rational design and synthesis of new selective COX-2 inhibitors with In Vivo PGE2-lowering activity by tethering benzenesulfonamide and 1, 2, 3-triazole pharmacophores to some … NH El-Dershaby, SA El-Hawash, SE Kassab, HG Daabees, ... Pharmaceuticals 15 (10), 1165, 2022 | 3 | 2022 |
Design, Synthesis, Biological Evaluation and Docking Studies of New Derivatives as Potent Antioxidants and 15-Lipoxygenase Inhibitors HS ElBordiny, MM El-Miligy, SE Kassab, H Daabees, AW Mohamed, ... Eur. J. Med. Chem 145, 594-605, 2018 | 2 | 2018 |
Discovery of new thymol-3,4-disubstituted thiazole hybrids as dual COX-2/5-LOX inhibitors with in vivo proof MMM El-Miligy, AK Al-Kubeisi, RA Nassra, SR El-Zemity, AA Hazzaa Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2309171, 2024 | | 2024 |
Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated … ME Abdelaziz, MMM El-Miligy, SM Fahmy, MM Abu-Serie, AA Hazzaa, ... Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2304044, 2024 | | 2024 |