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Lee Haynes
Lee Haynes
Senior lab manager, Pharmaron Biologics
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Neuronal Ca2+-sensor proteins: multitalented regulators of neuronal function
RD Burgoyne, DW O'Callaghan, B Hasdemir, LP Haynes, AV Tepikin
Trends in neurosciences 27 (4), 203-209, 2004
2532004
Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry
CM Walsh, M Chvanov, LP Haynes, OH Petersen, AV Tepikin, ...
Biochemical Journal 425 (1), 159-168, 2010
1832010
Interaction of neuronal calcium sensor-1 and ADP-ribosylation factor 1 allows bidirectional control of phosphatidylinositol 4-kinase β and trans-Golgi network-plasma membrane …
LP Haynes, GMH Thomas, RD Burgoyne
Journal of Biological Chemistry 280 (7), 6047-6054, 2005
1572005
Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP3 receptors
G Lur, LP Haynes, IA Prior, OV Gerasimenko, S Feske, OH Petersen, ...
Current Biology 19 (19), 1648-1653, 2009
1452009
Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1, 4, 5-trisphosphate-mediated calcium signaling
LP Haynes, AV Tepikin, RD Burgoyne
Journal of Biological Chemistry 279 (1), 547-555, 2004
1452004
The diversity of calcium sensor proteins in the regulation of neuronal function
HV McCue, LP Haynes, RD Burgoyne
Cold Spring Harbor perspectives in biology 2 (8), a004085, 2010
1122010
Understanding the physiological roles of the neuronal calcium sensor proteins
RD Burgoyne, LP Haynes
Molecular brain 5, 1-11, 2012
992012
The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic β-cell exocytosis
S Cheviet, T Coppola, LP Haynes, RD Burgoyne, R Regazzi
Molecular Endocrinology 18 (1), 117-126, 2004
892004
Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder
MTW Handley, LY Lian, LP Haynes, RD Burgoyne
PloS one 5 (5), e10534, 2010
822010
Calcium sensors in neuronal function and dysfunction
RD Burgoyne, N Helassa, HV McCue, LP Haynes
Cold Spring Harbor perspectives in biology 11 (5), a035154, 2019
802019
Differential dynamics of Rab3A and Rab27A on secretory granules
MTW Handley, LP Haynes, RD Burgoyne
Journal of cell science 120 (6), 973-984, 2007
732007
cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC
A Burdyga, A Conant, L Haynes, J Zhang, K Jalink, R Sutton, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2664-2672, 2013
722013
Analysis of the interacting partners of the neuronal calcium‐binding proteins L‐CaBP1, hippocalcin, NCS‐1 and neurocalcin δ
LP Haynes, DJ Fitzgerald, B Wareing, DW O'Callaghan, A Morgan, ...
Proteomics 6 (6), 1822-1832, 2006
722006
InsP3 receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences
G Lur, MW Sherwood, E Ebisui, L Haynes, S Feske, R Sutton, ...
Biochemical Journal 436 (2), 231-239, 2011
702011
Phospholipase D activity is essential for actin localization and actin-based motility in Dictyostelium
S Zouwail, TR Pettitt, SK Dove, MV Chibalina, DJ Powner, L Haynes, ...
Biochemical Journal 389 (1), 207-214, 2005
652005
Sense and specificity in neuronal calcium signalling
RD Burgoyne, LP Haynes
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (9), 1921-1932, 2015
632015
A direct inhibitory role for the Rab3-specific effector, Noc2, in Ca2+-regulated exocytosis in neuroendocrine cells
LP Haynes, GJO Evans, A Morgan, RD Burgoyne
Journal of Biological Chemistry 276 (13), 9726-9732, 2001
632001
Specificity, Promiscuity and Localization of ARF Protein Interactions with NCS‐1 and Phosphatidylinositol‐4 Kinase‐IIIβ
LP Haynes, MW Sherwood, NJ Dolman, RD Burgoyne
Traffic 8 (8), 1080-1092, 2007
562007
ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP
M Chvanov, CM Walsh, LP Haynes, SG Voronina, G Lur, ...
Pflügers Archiv-European Journal of Physiology 457, 505-517, 2008
552008
Evolution and functional diversity of the Calcium Binding Proteins (CaBPs)
LP Haynes, HV McCue, RD Burgoyne
Frontiers in molecular neuroscience 5, 9, 2012
512012
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