| p53 activates the long noncoding RNA Pvt1b to inhibit Myc and suppress tumorigenesis CE Olivero, E Martínez-Terroba, J Zimmer, C Liao, E Tesfaye, ... Molecular cell 77 (4), 761-774. e8, 2020 | 133 | 2020 |
| Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression NA Rosa-Mercado, JT Zimmer, M Apostolidi, J Rinehart, MD Simon, ... Molecular cell 81 (3), 502-513. e4, 2021 | 82 | 2021 |
| Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Molecular cell 82 (6), 1107-1122. e7, 2022 | 46 | 2022 |
| Functional elements of the cis-regulatory lincRNA-p21 L Winkler, M Jimenez, JT Zimmer, A Williams, MD Simon, N Dimitrova Cell reports 39 (3), 2022 | 31 | 2022 |
| STL-seq reveals pause-release and termination kinetics for promoter-proximal paused RNA polymerase II transcripts JT Zimmer, NA Rosa-Mercado, D Canzio, JA Steitz, MD Simon Molecular cell 81 (21), 4398-4412. e7, 2021 | 23 | 2021 |
| Acetyl-methyllysine marks chromatin at active transcription start sites WJ Lu-Culligan, LJ Connor, Y Xie, BE Ekundayo, BT Rose, M Machyna, ... Nature 622 (7981), 173-179, 2023 | 10 | 2023 |
| Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape PC Boddu, AK Gupta, R Roy, BDLP Avalos, A Olazabal-Herrero, ... Molecular Cell 84 (8), 1475-1495. e18, 2024 | 9 | 2024 |
| ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control Y Gao, JT Zimmer, R Vasic, C Liu, R Gbyli, SJ Zheng, A Patel, W Liu, Z Qi, ... Cell Reports 42 (10), 2023 | 9 | 2023 |
| Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC JC Swartzel, MJ Bond, AP Pintado-Urbanc, M Daftary, MW Krone, ... ACS chemical biology 17 (7), 1789-1798, 2022 | 5 | 2022 |
| Improving the study of RNA dynamics through advances in RNA-seq with metabolic labeling and nucleotide-recoding chemistry JT Zimmer, IW Vock, JA Schofield, L Kiefer, MH Moon, MD Simon bioRxiv, 2023 | 3 | 2023 |
| Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape PC Boddu, AK Gupta, R Roy, BDL Pena Avalos, AO Herrero, ... bioRxiv, 2023.02. 25.530019, 2023 | 3 | 2023 |
| Multi-omics profiling of U2AF1 mutants dissects pathogenic mechanisms affecting RNA granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... bioRxiv, 2021.04. 22.441020, 2021 | 3 | 2021 |
| The ubiquitin-protein ligase E6AP/UBE3A supports early encephalomyocarditis virus replication M Carmody, JT Zimmer, CH Cushman, T Nguyen, TG Lawson Virus research 252, 48-57, 2018 | 3 | 2018 |
| Impaired Early Spliceosome Complex Assembly Underlies Gene Body Elongation Transcription Defect in SF3B1K700E P Boddu, A Gupta, R Roy, AO Herrero, J Zimmer, M Simon, NS Chandhok, ... Blood 142, 714, 2023 | 1 | 2023 |
| THC Elicits Temporary or Persistent Changes in Expression of Genes Implicated in Neurodevelopment in Adolescent Rat Brain Regions BK Madras, GM Miller, L Ogawa, J Zimmer, E Vallender, Y Hurd, ... NEUROPSYCHOPHARMACOLOGY 38, S565-S566, 2013 | 1 | 2013 |
| 3064–ALKBH5 MODULATES HEMATOPOIETIC STEM AND PROGENITOR CELL ENERGY METABOLISM THROUGH M6A MODIFICATION-MEDIATED RNA STABILITY CONTROL Y Gao, G Biancon, R Flavell, R Gbyli, S Halene, R Kibbey, HB Li, Y Li, ... Experimental Hematology 124, S82, 2023 | | 2023 |
| U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Blood 138 (Supplement 1), 321-321, 2021 | | 2021 |
| High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies G Biancon, P Joshi, T Hunck, J Zimmer, Y Gao, M Machyna, V Botti, A Qin, ... Blood 136, 3-4, 2020 | | 2020 |
| Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repression NA Rosa-Mercado, JT Zimmer, M Apostolidi, J Rinehart, MD Simon, ... bioRxiv, 2020.06. 30.178103, 2020 | | 2020 |
