α cell function and gene expression are compromised in type 1 diabetes M Brissova, R Haliyur, D Saunders, S Shrestha, C Dai, DM Blodgett, ... Cell reports 22 (10), 2667-2676, 2018 | 184 | 2018 |
SARS-CoV-2 cell entry factors ACE2 and TMPRSS2 are expressed in the microvasculature and ducts of human pancreas but are not enriched in β cells KC Coate, J Cha, S Shrestha, W Wang, LM Gonçalves, J Almaça, ... Cell metabolism 32 (6), 1028-1040. e4, 2020 | 179 | 2020 |
The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity SG Alam, Q Zhang, N Prasad, Y Li, S Chamala, R Kuchibhotla, B Kc, ... Scientific reports 6 (1), 38063, 2016 | 156 | 2016 |
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks R Haliyur, X Tong, M Sanyoura, S Shrestha, J Lindner, DC Saunders, ... The Journal of clinical investigation 129 (1), 246-251, 2019 | 85 | 2019 |
A molecular genetic basis explaining altered bacterial behavior in space L Zea, N Prasad, SE Levy, L Stodieck, A Jones, S Shrestha, D Klaus PloS one 11 (11), e0164359, 2016 | 83 | 2016 |
Spaceflight Modifies Escherichia coli Gene Expression in Response to Antibiotic Exposure and Reveals Role of Oxidative Stress Response TR Aunins, KE Erickson, N Prasad, SE Levy, A Jones, S Shrestha, ... Frontiers in microbiology 9, 310, 2018 | 80 | 2018 |
Ectonucleoside triphosphate diphosphohydrolase-3 antibody targets adult human pancreatic β cells for in vitro and in vivo analysis DC Saunders, M Brissova, N Phillips, S Shrestha, JT Walker, ... Cell metabolism 29 (3), 745-754. e4, 2019 | 68 | 2019 |
Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors D Aslanoglou, S Bertera, M Sánchez-Soto, R Benjamin Free, J Lee, ... Translational psychiatry 11 (1), 59, 2021 | 67 | 2021 |
A high-throughput molecular data resource for cutaneous neurofibromas SJC Gosline, H Weinberg, P Knight, T Yu, X Guo, N Prasad, A Jones, ... Scientific data 4 (1), 1-9, 2017 | 27 | 2017 |
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells JCI Insight 6 (18), e151621, 2021 | 26 | 2021 |
Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress S Shrestha, G Erikson, J Lyon, AF Spigelman, A Bautista, JE Manning Fox, ... Science Advances 8 (40), eabo3932, 2022 | 24 | 2022 |
Single-cell sperm transcriptomes and variants from fathers of children with and without autism spectrum disorder D Tomoiaga, V Aguiar-Pulido, S Shrestha, P Feinstein, SE Levy, ... NPJ genomic medicine 5 (1), 14, 2020 | 17 | 2020 |
Phytochemical Screening, Antimicrobial Activity and Cytotoxicity of Nepalese Medicinal Plants Swertia chirayita and Dendrobium amoenum. P Shrestha, M Bista, P Sharma, S Shrestha, B Lamichhane, S Adhikari, ... Nepal Journal of Biotechnology 3 (1), 2015 | 16 | 2015 |
Spaceflight modifies escherichia coli gene expression in response to antibiotic exposure and reveals role of oxidative stress response. Front Microbiol. 2018; 9: 310. Published … TR Aunins, KE Erickson, N Prasad, SE Levy, A Jones, S Shrestha, ... | 15 | 2018 |
RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes JT Walker, DC Saunders, V Rai, C Dai, P Orchard, AL Hopkirk, ... BioRxiv, 2021.12. 16.466282, 2021 | 9 | 2021 |
Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss TM Richardson, DC Saunders, R Haliyur, S Shrestha, JP Cartailler, ... American Journal of Physiology-Endocrinology and Metabolism 324 (3), E251-E267, 2023 | 7 | 2023 |
ZFP92, a KRAB domain zinc finger protein enriched in pancreatic islets, binds to B1/Alu SINE transposable elements and regulates retroelements and genes AB Osipovich, KD Dudek, LT Trinh, LH Kim, S Shrestha, JP Cartailler, ... PLoS Genetics 19 (5), e1010729, 2023 | 5 | 2023 |
Genetic risk converges on regulatory networks mediating early type 2 diabetes. JT Walker, DC Saunders, V Rai, HH Chen, P Orchard, C Dai, YD Pettway, ... Nature, 2023 | 4 | 2023 |
Protein kinase D1 (Prkd1) deletion in brown adipose tissue leads to altered myogenic gene expression after cold exposure, while thermogenesis remains intact MK Crowder, S Shrestha, JP Cartailler, S Collins Physiological Reports 11 (4), e15576, 2023 | 3 | 2023 |
Single-Cell RNA Sequencing of Sox17-Expressing Lineages Reveals Distinct Gene Regulatory Networks and Dynamic Developmental Trajectories LT Trinh, AB Osipovich, B Liu, S Shrestha, JP Cartailler, CVE Wright, ... Stem Cells 41 (6), 643-657, 2023 | 2 | 2023 |