Herbal hepatotoxicity: current status, examples, and challenges C Calitz, L Du Plessis, C Gouws, D Steyn, J Steenekamp, C Muller, ... Expert opinion on drug metabolism & toxicology 11 (10), 1551-1565, 2015 | 58 | 2015 |
Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma N Pavlović, C Calitz, K Thanapirom, G Mazza, K Rombouts, P Gerwins, ... Elife 9, e55865, 2020 | 38 | 2020 |
Recent Advances in Three-Dimensional Cell Culturing to Assess Liver Function and Dysfunction: From a Drug Biotransformation and Toxicity Perspective C Calitz, JH Hamman, SJ Fey, K Wrzesinski, C Gouws Toxicology Mechanisms and Methods, 1-17, 2018 | 32 | 2018 |
In vitro cell toxicity and intracellular uptake of doxorubicin exposed as a solution or liposomes: Implications for treatment of hepatocellular carcinoma F Kullenberg, O Degerstedt, C Calitz, N Pavlović, D Balgoma, J Gråsjö, ... Cells 10 (7), 1717, 2021 | 31 | 2021 |
A biomimetic model for liver Cancer to study Tumor-Stroma interactions in a 3D environment with tunable Bio-Physical properties C Calitz, N Pavlović, J Rosenquist, C Zagami, A Samanta, F Heindryckx JoVE (Journal of Visualized Experiments), e61606, 2020 | 26 | 2020 |
Characterization of an alginate encapsulated LS180 spheroid model for anti-colorectal cancer compound screening T Smit, C Calitz, C Willers, H Svitina, J Hamman, SJ Fey, C Gouws, ... ACS medicinal chemistry letters 11 (5), 1014-1021, 2020 | 21 | 2020 |
Cell-free DNA in a three-dimensional spheroid cell culture model: A preliminary study J Aucamp, C Calitz, AJ Bronkhorst, K Wrzesinski, S Hamman, C Gouws, ... The International Journal of Biochemistry & Cell Biology 89, 182-192, 2017 | 20 | 2017 |
Anthracyclins increase PUFAs: potential implications in ER stress and cell death D Balgoma, F Kullenberg, C Calitz, M Kopsida, F Heindryckx, ... Cells 10 (5), 1163, 2021 | 19 | 2021 |
Fibrin fragment E potentiates TGF-β-induced myofibroblast activation and recruitment PÖ Fuchs, C Calitz, N Pavlović, F Binet, SMØ Solbak, UH Danielson, ... Cellular signalling 72, 109661, 2020 | 15 | 2020 |
Impact of traditional African medicine on drug metabolism and transport C Calitz, JH Steenekamp, JD Steyn, C Gouws, JM Viljoen, JH Hamman Expert opinion on drug metabolism & toxicology 10 (7), 991-1003, 2014 | 15 | 2014 |
Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell … C Calitz, JH Hamman, AM Viljoen, SJ Fey, K Wrzesinski, C Gouws Toxicology mechanisms and methods 28 (9), 641-652, 2018 | 14 | 2018 |
Herb-drug pharmacokinetic interactions: transport and metabolism of indinavir in the presence of selected herbal products C Calitz, C Gouws, J Viljoen, J Steenekamp, L Wiesner, E Abay, ... Molecules 20 (12), 22113-22127, 2015 | 13 | 2015 |
Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors C Gouws, T Smit, C Willers, H Svitina, C Calitz, K Wrzesinski Molecules 26 (3), 605, 2021 | 12 | 2021 |
A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model C Calitz, JH Hamman, SJ Fey, AM Viljoen, C Gouws, K Wrzesinski Journal of ethnopharmacology 239, 111897, 2019 | 12 | 2019 |
Human milk inhibits some enveloped virus infections, including SARS-CoV-2, in an intestinal model I Aknouch, A Sridhar, E Freeze, FP Giugliano, BJ van Keulen, M Romijn, ... Life Science Alliance 5 (12), 2022 | 11 | 2022 |
Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma C Calitz, J Rosenquist, O Degerstedt, J Khaled, M Kopsida, M Fryknäs, ... Scientific Reports 13 (1), 748, 2023 | 10 | 2023 |
Clinostat 3D cell culture: protocols for the preparation and functional analysis of highly reproducible, large, uniform spheroids and organoids K Wrzesinski, HS Frandsen, C Calitz, C Gouws, B Korzeniowska, SJ Fey Next Generation Culture Platforms for Reliable In Vitro Models: Methods and …, 2021 | 6 | 2021 |
Non-Polio Enterovirus C Replicate in Both Airway and Intestine Organotypic Cultures G Moreni, H van Eijk, G Koen, N Johannesson, C Calitz, K Benschop, ... Viruses 15 (9), 1823, 2023 | 5 | 2023 |
Amino acid variation at VP1-145 of enterovirus A71 determines the viral infectivity and receptor usage in a primary human intestinal model I Aknouch, I García-Rodríguez, FP Giugliano, C Calitz, G Koen, H van Eijk, ... Frontiers in Microbiology 14, 1045587, 2023 | 5 | 2023 |
Bridging the gap between emerging models and humans by learning from polio animal studies: A systematic review G Moreni, I Aknouch, M Ras, L Brouwer, R Spijker, C Calitz, KJ Stittelaar, ... Clinical and Translational Discovery 2 (2), e42, 2022 | 5 | 2022 |