| Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms L Gao, M Emperle, Y Guo, SA Grimm, W Ren, S Adam, H Uryu, ZM Zhang, ... Nature communications 11 (1), 3355, 2020 | 144 | 2020 |
| Polycomb gene silencing mechanisms: PRC2 chromatin targeting, H3K27me3'readout', and phase separation-based compaction Y Guo, S Zhao, GG Wang Trends in Genetics 37 (6), 547-565, 2021 | 100 | 2021 |
| Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation W Ren, H Fan, SA Grimm, Y Guo, JJ Kim, J Yin, L Li, CJ Petell, XF Tan, ... Proceedings of the National Academy of Sciences 117 (31), 18439-18447, 2020 | 83 | 2020 |
| DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation W Ren, H Fan, SA Grimm, JJ Kim, L Li, Y Guo, CJ Petell, XF Tan, ... Nature communications 12 (1), 2490, 2021 | 76 | 2021 |
| BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis H Fan, J Lu, Y Guo, D Li, ZM Zhang, YH Tsai, WC Pi, JH Ahn, W Gong, ... Nature genetics 52 (12), 1384-1396, 2020 | 74 | 2020 |
| ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism J Li, PM Galbo Jr, W Gong, AJ Storey, YH Tsai, X Yu, JH Ahn, Y Guo, ... Nature communications 12 (1), 1045, 2021 | 34 | 2021 |
| Histone H3 proline 16 hydroxylation regulates mammalian gene expression X Liu, J Wang, JA Boyer, W Gong, S Zhao, L Xie, Q Wu, C Zhang, K Jain, ... Nature genetics 54 (11), 1721-1735, 2022 | 28 | 2022 |
| A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing H Fan, Y Guo, YH Tsai, AJ Storey, A Kim, W Gong, RD Edmondson, ... Nucleic acids research 49 (8), 4441-4455, 2021 | 23 | 2021 |
| Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion Y Zhang, Y Guo, SM Gough, J Zhang, KR Vann, K Li, L Cai, X Shi, ... Nature Communications 11 (1), 3339, 2020 | 22 | 2020 |
| Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations L Gao, Y Guo, M Biswal, J Lu, J Yin, J Fang, X Chen, Z Shao, M Huang, ... Nature communications 13 (1), 4249, 2022 | 13 | 2022 |
| TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons S Zhao, J Lu, B Pan, H Fan, SD Byrum, C Xu, A Kim, Y Guo, KL Kanchi, ... Nature 623 (7987), 633-642, 2023 | 12 | 2023 |
| Modulation of the high-order chromatin structure by Polycomb complexes Y Guo, GG Wang Frontiers in cell and developmental biology 10, 1021658, 2022 | 10 | 2022 |
| Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations J Lu, Y Guo, J Yin, J Chen, Y Wang, GG Wang, J Song Nature Communications 15 (1), 3111, 2024 | 3 | 2024 |
| Polycomb Repressive Complex 2 in Oncology Y Guo, Y Yu, GG Wang Epigenetics in Oncology, 273-320, 2023 | 2 | 2023 |
| Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction X Chen, Y Guo, T Zhao, J Lu, J Fang, Y Wang, GG Wang, J Song Nature Communications 15 (1), 6217, 2024 | | 2024 |
