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Leonard Kaysser
Leonard Kaysser
Professor für Pharmazeutische Biologie, Universität Leipzig
在 uni-leipzig.de 的电子邮件经过验证
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Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
8722015
Cytochrome P450 alkane hydroxylases of the CYP153 family are common in alkane-degrading eubacteria lacking integral membrane alkane hydroxylases
JB van Beilen, EG Funhoff, A van Loon, A Just, L Kaysser, M Bouza, ...
Applied and environmental microbiology 72 (1), 59-65, 2006
3592006
Merochlorins A–D, cyclic meroterpenoid antibiotics biosynthesized in divergent pathways with vanadium-dependent chloroperoxidases
L Kaysser, P Bernhardt, SJ Nam, S Loesgen, JG Ruby, P Skewes-Cox, ...
Journal of the American Chemical Society 134 (29), 11988-11991, 2012
2102012
Catalytic hydroxylation in biphasic systems using CYP102A1 mutants
SC Maurer, K Kühnel, LA Kaysser, S Eiben, RD Schmid, VB Urlacher
Advanced Synthesis & Catalysis 347 (7‐8), 1090-1098, 2005
1372005
Identification and manipulation of the caprazamycin gene cluster lead to new simplified liponucleoside antibiotics and give insights into the biosynthetic pathway
L Kaysser, L Lutsch, S Siebenberg, E Wemakor, B Kammerer, B Gust
Journal of Biological Chemistry 284 (22), 14987-14996, 2009
1122009
A community resource for paired genomic and metabolomic data mining
MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ...
Nature Chemical Biology 17 (4), 363-368, 2021
1042021
One‐pot enzymatic synthesis of merochlorin A and B
R Teufel, L Kaysser, MT Villaume, S Diethelm, MK Carbullido, PS Baran, ...
Angewandte Chemie International Edition 53 (41), 11019-11022, 2014
962014
Preparative use of isolated CYP102 monooxygenases—a critical appraisal
S Eiben, L Kaysser, S Maurer, K Kühnel, VB Urlacher, RD Schmid
Journal of biotechnology 124 (4), 662-669, 2006
942006
A Multitasking Vanadium‐Dependent Chloroperoxidase as an Inspiration for the Chemical Synthesis of the Merochlorins
S Diethelm, R Teufel, L Kaysser, BS Moore
Angewandte Chemie International Edition 53 (41), 11023-11026, 2014
792014
Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors
M Schorn, J Zettler, JP Noel, PC Dorrestein, BS Moore, L Kaysser
ACS chemical biology 9 (1), 301-309, 2014
642014
Analysis of the liposidomycin gene cluster leads to the identification of new caprazamycin derivatives
L Kaysser, S Siebenberg, B Kammerer, B Gust
ChemBioChem 11 (2), 191-196, 2010
632010
Identification of a napsamycin biosynthesis gene cluster by genome mining
L Kaysser, X Tang, E Wemakor, K Sedding, S Hennig, S Siebenberg, ...
Chembiochem 12 (3), 477-487, 2011
612011
Heterologous expression of the biosynthetic gene clusters of coumermycin A1, clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains
K Flinspach, L Westrich, L Kaysser, S Siebenberg, JP Gomez‐Escribano, ...
Biopolymers 93 (9), 823-832, 2010
482010
A new arylsulfate sulfotransferase involved in liponucleoside antibiotic biosynthesis in streptomycetes
L Kaysser, K Eitel, T Tanino, S Siebenberg, A Matsuda, S Ichikawa, ...
Journal of Biological Chemistry 285 (17), 12684-12694, 2010
462010
Biosynthesis of the β‐Lactone Proteasome Inhibitors Belactosin and Cystargolide
F Wolf, JS Bauer, TM Bendel, A Kulik, J Kalinowski, H Gross, L Kaysser
Angewandte Chemie International Edition 56 (23), 6665-6668, 2017
432017
Formation and attachment of the deoxysugar moiety and assembly of the gene cluster for caprazamycin biosynthesis
L Kaysser, E Wemakor, S Siebenberg, JA Salas, JK Sohng, B Kammerer, ...
Applied and Environmental Microbiology 76 (12), 4008-4018, 2010
422010
Comparative Genomics and Metabolomics in the Genus Nocardia
D Männle, SMK McKinnie, SS Mantri, K Steinke, Z Lu, BS Moore, ...
Msystems 5 (3), 10.1128/msystems. 00125-20, 2020
412020
A two-step sulfation in antibiotic biosynthesis requires a type III polyketide synthase
X Tang, K Eitel, L Kaysser, A Kulik, S Grond, B Gust
Nature chemical biology 9 (10), 610-615, 2013
412013
Warhead biosynthesis and the origin of structural diversity in hydroxamate metalloproteinase inhibitors
F Leipoldt, J Santos-Aberturas, DP Stegmann, F Wolf, A Kulik, R Lacret, ...
Nature Communications 8 (1), 1965, 2017
402017
Stereodivergent nitrocyclopropane formation during biosynthesis of belactosins and hormaomycins
S Shimo, R Ushimaru, A Engelbrecht, M Harada, K Miyamoto, A Kulik, ...
Journal of the American Chemical Society 143 (44), 18413-18418, 2021
362021
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