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Charlotte Toomes
Charlotte Toomes
其他姓名CEJ Downes
Postdoctoral Researcher, Flinders Universty
在 flinders.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies
CEJ Downes, BJ McClure, DP McDougal, SL Heatley, JB Bruning, ...
Frontiers in Cell and Developmental Biology 10, 942053, 2022
232022
Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia
CEJ Downes, BJ McClure, JB Bruning, E Page, J Breen, J Rehn, ...
NPJ precision oncology 5 (1), 75, 2021
182021
Identification of a novel GOLGA4–JAK2 fusion gene in B‐cell acute lymphoblastic leukaemia
CEJ Downes, J Rehn, SL Heatley, D Yeung, BJ McClure, DL White
British Journal of Haematology 196 (3), 700-705, 2022
52022
Acquired mutations within the jak2 kinase domain confer resistance to jak inhibitors in an in vitro model of a high-risk acute lymphoblastic leukemia
CEJ Downes, BJ McClure, J Rehn, J Breen, JB Bruning, DT Yeung, ...
Blood 136, 5-6, 2020
22020
Case Report: Rare IKZF1 Gene Fusions Identified in Neonate with Congenital KMT2A-Rearranged Acute Lymphoblastic Leukemia
LN Eadie, JA Rehn, J Breen, MP Osborn, S Jessop, CEJ Downes, ...
Genes 14 (2), 264, 2023
12023
P-284 Elevated Desmoglein-2 Surface Expression Is an Independent Predictor of Poor Outcome in Multiple Myeloma
C Toomes, B McClure, G Best, L Ebert, K Vandyke, M Cockshell, T Day, ...
Clinical Lymphoma Myeloma and Leukemia 24, S199-S200, 2024
2024
Precision Medicine Approaches for JAK2-Rearranged Acute Lymphoblastic Leukaemia: The Efficacy of Targeted Therapies and Molecular Mechanisms of Drug Resistance
CEJ Downes
2022
Acquired mutations within the JAK2 kinase domain confer resistance to JAK inhibitors in in vitro models of acute lymphoblastic leukaemia
C Downes, B McClure, J Bruning, J Breen, J Rehn, D Yeung, DL White
Blood 2021 Annual Scientific Meeting, 2021
2021
Acquired Mutations within the JAK2 Kinase Domain confer Resistance to JAK Inhibitors in in vitro Models of High-Risk ALL
CEJ Downes, BJ McClure, JB Bruning, J Breen, JA Rehn, DT Yeung, ...
European School of Haematology (ESH) 2nd Translational Research Conference …, 2021
2021
JAK2 kinase domain mutations confer resistance to JAK inhibitors in a pro-B cell model of a high-risk acute lymphoblastic leukaemia
CEJ Downes, BJ McClure, JB Bruning, SL Heatley, CH Kok, TP Hughes, ...
Australian Society for Medical Research South Australian Scientific Meeting …, 2019
2019
Identification of ruxolitinib resistant mutations in Pro-B cells driven by a high-risk JAK2 fusion in B-cell acute lymphoblastic leukaemia
CEJ Downes, BJ McClure, B Mayne, JB Bruning, SL Heatley, CH Kok, ...
Australian Society for Medical Research SA Meeting 2018, 2018
2018
Identification and characterisation of ruxolitinib resistant mutations in pro-B cell model of high-risk acute lymphoblastic leukaemia
CEJ Downes, BJ McClure, B Mayne, JB Bruning, S Heatley, C Kok, ...
Australasian Genomic Technologies Association (AGTA) 2018 Annual Conference, 2018
2018
Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell acute lymphoblastic leukaemia
CEJ Downes, BJ McClure, S Heatley, T Sadras, TP Hughes, CH Kok, ...
Australian Society for Medical Research (ASMR) SA Meeting 2017, 2017
2017
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