| Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy N Tsybouleva, L Zhang, S Chen, R Patel, S Lutucuta, S Nemoto, ... Circulation 109 (10), 1284-1291, 2004 | 294 | 2004 |
| The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy SN Chen, P Gurha, R Lombardi, A Ruggiero, JT Willerson, AJ Marian Circulation research 114 (3), 454-468, 2014 | 291 | 2014 |
| Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy A Osio, L Tan, SN Chen, R Lombardi, SF Nagueh, S Shete, R Roberts, ... Circulation research 100 (6), 766-768, 2007 | 219 | 2007 |
| A Common PCSK9Haplotype, Encompassing the E670G Coding Single Nucleotide Polymorphism, Is a Novel Genetic Marker for Plasma Low-Density Lipoprotein … SN Chen, CM Ballantyne, AM Gotto, Y Tan, JT Willerson, AJ Marian Journal of the American College of Cardiology 45 (10), 1611-1619, 2005 | 203 | 2005 |
| Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy V Senthil, SN Chen, N Tsybouleva, T Halder, SF Nagueh, JT Willerson, ... Circulation research 97 (3), 285-292, 2005 | 192 | 2005 |
| Human Molecular Genetic and Functional Studies Identify TRIM63, Encoding Muscle RING Finger Protein 1, as a Novel Gene for Human Hypertrophic … SN Chen, G Czernuszewicz, Y Tan, R Lombardi, J Jin, JT Willerson, ... Circulation research 111 (7), 907-919, 2012 | 156 | 2012 |
| Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive … R Lombardi, G Rodriguez, SN Chen, CM Ripplinger, W Li, J Chen, ... Circulation 119 (10), 1398-1407, 2009 | 144 | 2009 |
| Antifibrotic effects of antioxidant N-acetylcysteine in a mouse model of human hypertrophic cardiomyopathy mutation AJ Marian, V Senthil, SN Chen, R Lombardi Journal of the American College of Cardiology 47 (4), 827-834, 2006 | 136 | 2006 |
| DNA damage response/TP53 pathway is activated and contributes to the pathogenesis of dilated cardiomyopathy associated with LMNA (Lamin A/C) mutations SN Chen, R Lombardi, J Karmouch, JY Tsai, G Czernuszewicz, ... Circulation research 124 (6), 856-873, 2019 | 123 | 2019 |
| The double substrate growth kinetics of Pseudomonas aeruginosa H Beyenal, SN Chen, Z Lewandowski Enzyme and Microbial Technology 32 (1), 92-98, 2003 | 109 | 2003 |
| Cardiac fibro-adipocyte progenitors express desmosome proteins and preferentially differentiate to adipocytes upon deletion of the desmoplakin gene R Lombardi, SN Chen, A Ruggiero, P Gurha, GZ Czernuszewicz, ... Circulation research 119 (1), 41-54, 2016 | 99 | 2016 |
| Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy EW Daw, SN Chen, G Czernuszewicz, R Lombardi, Y Lu, J Ma, R Roberts, ... Human molecular genetics 16 (20), 2463-2471, 2007 | 89 | 2007 |
| Effects of PPARα, γ and δ haplotypes on plasma levels of lipids, severity and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary … S Chen, N Tsybouleva, CM Ballantyne, AM Gotto Jr, AJ Marian Pharmacogenetics and Genomics 14 (1), 61-71, 2004 | 76 | 2004 |
| Phenotypic expression, natural history, and risk stratification of cardiomyopathy caused by filamin C truncating variants M Gigli, D Stolfo, SL Graw, M Merlo, C Gregorio, S Nee Chen, M Dal Ferro, ... Circulation 144 (20), 1600-1611, 2021 | 75 | 2021 |
| Evolution of expression of cardiac phenotypes over a 4-year period in the β-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy SF Nagueh, S Chen, R Patel, N Tsybouleva, S Lutucuta, HA Kopelen, ... Journal of molecular and cellular cardiology 36 (5), 663-673, 2004 | 71 | 2004 |
| Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis SN Chen, M Cilingiroglu, J Todd, R Lombardi, JT Willerson, AM Gotto, ... BMC medical genetics 10, 1-8, 2009 | 64 | 2009 |
| Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity A Ruggiero, SN Chen, R Lombardi, G Rodriguez, AJ Marian Cardiovascular research 97 (1), 44-54, 2013 | 59 | 2013 |
| The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis SN Chen, CM Ballantyne, AM Gotto, AJ Marian BMC cardiovascular disorders 9, 1-10, 2009 | 50 | 2009 |
| Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins E Laurini, V Martinelli, T Lanzicher, L Puzzi, D Borin, SN Chen, CS Long, ... Cardiovascular research 114 (6), 846-857, 2018 | 44 | 2018 |
| Genetics of dilated cardiomyopathy SN Chen, L Mestroni, MRG Taylor Current opinion in cardiology 36 (3), 288-294, 2021 | 33 | 2021 |
