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Steven W Hardwick
Steven W Hardwick
Department of Biochemistry, University of Cambridge
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Single-particle cryo-EM at atomic resolution
T Nakane, A Kotecha, A Sente, G McMullan, S Masiulis, PMGE Brown, ...
Nature 587 (7832), 152-156, 2020
8352020
Nanopore-based identification of individual nucleotides for direct RNA sequencing
M Ayub, SW Hardwick, BF Luisi, H Bayley
Nano letters 13 (12), 6144-6150, 2013
1402013
Functional and structural characterization of RsbU, a stress signaling protein phosphatase 2C
O Delumeau, S Dutta, M Brigulla, G Kuhnke, SW Hardwick, U Völker, ...
Journal of Biological Chemistry 279 (39), 40927-40937, 2004
1082004
An RNA degradosome assembly in Caulobacter crescentus
SW Hardwick, VSY Chan, RW Broadhurst, BF Luisi
Nucleic acids research 39 (4), 1449-1459, 2011
972011
Dimers of DNA-PK create a stage for DNA double-strand break repair
AK Chaplin, SW Hardwick, S Liang, A Kefala Stavridi, A Hnizda, ...
Nature structural & molecular biology 28 (1), 13-19, 2021
872021
CryoEM structures of human CMG–ATPγS–DNA and CMG–AND-1 complexes
NJ Rzechorzek, SW Hardwick, VA Jatikusumo, DY Chirgadze, L Pellegrini
Nucleic acids research 48 (12), 6980-6995, 2020
812020
Role of RsbU in Controlling SigB Activity in Staphylococcus aureus following Alkaline Stress
J Pané-Farré, B Jonas, SW Hardwick, K Gronau, RJ Lewis, M Hecker, ...
Journal of bacteriology 191 (8), 2561-2573, 2009
812009
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair
AK Chaplin, SW Hardwick, AK Stavridi, CJ Buehl, NJ Goff, V Ropars, ...
Molecular cell 81 (16), 3400-3409. e3, 2021
732021
Differential assembly diversifies GABAA receptor structures and signalling
A Sente, R Desai, K Naydenova, T Malinauskas, Y Jounaidi, J Miehling, ...
Nature 604 (7904), 190-194, 2022
672022
Structure of the Escherichia coli ProQ RNA-binding protein
GM Gonzalez, SW Hardwick, SL Maslen, JM Skehel, E Holmqvist, J Vogel, ...
Rna 23 (5), 696-711, 2017
662017
Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly
SW Hardwick, T Gubbey, I Hug, U Jenal, BF Luisi
Open biology 2 (4), 120028, 2012
662012
Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs
S Liang, SE Thomas, AK Chaplin, SW Hardwick, DY Chirgadze, ...
Nature 601 (7894), 643-648, 2022
612022
Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome
A Van den Bossche, SW Hardwick, PJ Ceyssens, H Hendrix, M Voet, ...
Elife 5, e16413, 2016
542016
Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control
SW Hardwick, BF Luisi
RNA biology 10 (1), 56-70, 2013
532013
Mechanisms of inhibition and activation of extrasynaptic αβ GABAA receptors
VB Kasaragod, M Mortensen, SW Hardwick, AA Wahid, V Dorovykh, ...
Nature 602 (7897), 529-533, 2022
502022
Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis
SW Hardwick, J Pané-Farré, O Delumeau, J Marles-Wright, JW Murray, ...
Journal of Biological Chemistry 282 (15), 11562-11572, 2007
462007
Association of the cold shock DEAD-box RNA helicase RhlE to the RNA degradosome in Caulobacter crescentus
AA Aguirre, AM Vicente, SW Hardwick, DM Alvelos, RR Mazzon, BF Luisi, ...
Journal of bacteriology 199 (13), 10.1128/jb. 00135-17, 2017
342017
Molecular recognition of RhlB and RNase D in the Caulobacter crescentus RNA degradosome
JE Voss, BF Luisi, SW Hardwick
Nucleic Acids Research 42 (21), 13294-13305, 2014
342014
Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism
GM Gonzalez, S Durica-Mitic, SW Hardwick, MC Moncrieffe, M Resch, ...
Nucleic Acids Research 45 (18), 10845-10860, 2017
332017
Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA polymerase α–primase
ML Kilkenny, CE Veale, A Guppy, SW Hardwick, DY Chirgadze, ...
Protein Science 31 (2), 333-344, 2022
292022
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