Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer APDA Bom, LP Rangel, DCF Costa, GAP de Oliveira, D Sanches, ... Journal of Biological Chemistry 287 (33), 28152-28162, 2012 | 311 | 2012 |
High-pressure chemical biology and biotechnology JL Silva, AC Oliveira, TCRG Vieira, GAP de Oliveira, MC Suarez, ... Chemical reviews 114 (14), 7239-7267, 2014 | 216 | 2014 |
Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer GAPO Jerson L. Silva, Elio A. Cino, Iaci N. Soares, Vitor F. Ferreira Acc. Chem. Res. 51, 181-190, 2018 | 116 | 2018 |
Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson’s disease GAP de Oliveira, JL Silva Communications biology 2 (1), 374, 2019 | 113 | 2019 |
Aggregation and prion-like properties of misfolded tumor suppressors: is cancer a prion disease? DCF Costa, GAP de Oliveira, EA Cino, IN Soares, LP Rangel, JL Silva Cold Spring Harbor perspectives in biology 8 (10), a023614, 2016 | 92 | 2016 |
A hypothesis to reconcile the physical and chemical unfolding of proteins GAP de Oliveira, JL Silva Proceedings of the National Academy of Sciences 112 (21), E2775-E2784, 2015 | 83 | 2015 |
The solution structure and dynamics of full-length human cerebral dopamine neurotrophic factor and its neuroprotective role against α-synuclein oligomers C Latge, KMS Cabral, GAP de Oliveira, DP Raymundo, JA Freitas, ... Journal of Biological Chemistry 290 (33), 20527-20540, 2015 | 62 | 2015 |
Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds EA Cino, IN Soares, MM Pedrote, GAP de Oliveira, JL Silva Scientific Reports 6 (1), 32535, 2016 | 60 | 2016 |
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands EC Petronilho, MM Pedrote, MA Marques, YM Passos, MF Mota, ... Chemical science 12 (21), 7334-7349, 2021 | 59 | 2021 |
Liquid-liquid phase transitions and amyloid aggregation in proteins related to cancer and neurodegenerative diseases GAP de Oliveira, Y Cordeiro, JL Silva, TCRG Vieira Advances in protein chemistry and structural biology 118, 289-331, 2019 | 58 | 2019 |
Misfolding, aggregation, and disordered segments in c-Abl and p53 in human cancer GAP de Oliveira, LP Rangel, DC Costa, JL Silva Frontiers in Oncology 5, 97, 2015 | 52 | 2015 |
Expression of metalloproteinases and their tissue inhibitors in inflamed gingival biopsies LDR GONCALVES, G Oliveira, PA Hurtado, A Feitosa, CM Thakyia, ... Journal of Periodontal Research 43, 570-577, 2008 | 51 | 2008 |
The status of p53 oligomeric and aggregation states in cancer GAP de Oliveira, EC Petronilho, MM Pedrote, MA Marques, TCRG Vieira, ... Biomolecules 10 (4), 548, 2020 | 48 | 2020 |
Oncogenic gain of function in glioblastoma is linked to mutant p53 amyloid oligomers MM Pedrote, MF Motta, GDS Ferretti, DR Norberto, TCLS Spohr, ... Iscience 23 (2), 2020 | 48 | 2020 |
An extensively glycosylated archaeal pilus survives extreme conditions F Wang, V Cvirkaite-Krupovic, MAB Kreutzberger, Z Su, GAP de Oliveira, ... Nature microbiology 4 (8), 1401-1410, 2019 | 45 | 2019 |
Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells NM Dos Santos, GAP de Oliveira, MR Rocha, MM Pedrote, ... Journal of Biological Chemistry 294 (24), 9430-9439, 2019 | 45 | 2019 |
Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core GAP de Oliveira, MA Marques, C Cruzeiro-Silva, Y Cordeiro, C Schuabb, ... Scientific reports 6 (1), 37990, 2016 | 43 | 2016 |
Cardiac troponin and tropomyosin: structural and cellular perspectives to unveil the hypertrophic cardiomyopathy phenotype MA Marques, GAP De Oliveira Frontiers in physiology 7, 429, 2016 | 38 | 2016 |
Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer MM Pedrote, GAP de Oliveira, AL Felix, MF Mota, MA Marques, IN Soares, ... Journal of Biological Chemistry 293 (29), 11374-11387, 2018 | 37 | 2018 |
A packing for A-form DNA in an icosahedral virus F Wang, Y Liu, Z Su, T Osinski, GAP de Oliveira, JF Conway, S Schouten, ... Proceedings of the National Academy of Sciences 116 (45), 22591-22597, 2019 | 33 | 2019 |