Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis BA Johnson, X Xie, AL Bailey, B Kalveram, KG Lokugamage, A Muruato, ... Nature 591 (7849), 293-299, 2021 | 637 | 2021 |
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation H Neumann, SM Hancock, R Buning, A Routh, L Chapman, J Somers, ... Molecular cell 36 (1), 153-163, 2009 | 577 | 2009 |
A screen of FDA-approved drugs for inhibitors of Zika virus infection NJ Barrows, RK Campos, ST Powell, KR Prasanth, G Schott-Lerner, ... Cell host & microbe 20 (2), 259-270, 2016 | 564 | 2016 |
Nucleosome repeat length and linker histone stoichiometry determine chromatin fiber structure A Routh, S Sandin, D Rhodes Proceedings of the National Academy of Sciences 105 (26), 8872-8877, 2008 | 430 | 2008 |
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction PJJ Robinson, W An, A Routh, F Martino, L Chapman, RG Roeder, ... Journal of molecular biology 381 (4), 816-825, 2008 | 390 | 2008 |
Single-molecule force spectroscopy reveals a highly compliant helical folding for the 30-nm chromatin fiber M Kruithof, FT Chien, A Routh, C Logie, D Rhodes, J Van Noort Nature structural & molecular biology 16 (5), 534-540, 2009 | 325 | 2009 |
The coronavirus proofreading exoribonuclease mediates extensive viral recombination J Gribble, LJ Stevens, ML Agostini, J Anderson-Daniels, JD Chappell, ... PLoS pathogens 17 (1), e1009226, 2021 | 234 | 2021 |
High-fidelity mass analysis unveils heterogeneity in intact ribosomal particles M Van De Waterbeemd, KL Fort, D Boll, M Reinhardt-Szyba, A Routh, ... Nature methods 14 (3), 283-286, 2017 | 194 | 2017 |
Furin cleavage site is key to SARS-CoV-2 pathogenesis BA Johnson, X Xie, B Kalveram, KG Lokugamage, A Muruato, J Zou, ... BioRxiv, 2020 | 186 | 2020 |
Host RNAs, including transposons, are encapsidated by a eukaryotic single-stranded RNA virus A Routh, T Domitrovic, JE Johnson Proceedings of the National Academy of Sciences, 2012 | 129 | 2012 |
Nucleocapsid mutations in SARS-CoV-2 augment replication and pathogenesis BA Johnson, Y Zhou, KG Lokugamage, MN Vu, N Bopp, ... PLoS pathogens 18 (6), e1010627, 2022 | 114 | 2022 |
Dengue NS2A protein orchestrates virus assembly X Xie, J Zou, X Zhang, Y Zhou, AL Routh, C Kang, VL Popov, X Chen, ... Cell host & microbe 26 (5), 606-622. e8, 2019 | 98 | 2019 |
Discovery of functional genomic motifs in viruses with ViReMa–a Virus Recombination Mapper–for analysis of next-generation sequencing data A Routh, JE Johnson Nucleic Acids Research 42 (2), e11-e11, 2014 | 83 | 2014 |
Biophysical characterization of Vpu from HIV‐1 suggests a channel‐pore dualism T Mehnert, A Routh, PJ Judge, YH Lam, D Fischer, A Watts, WB Fischer Proteins: Structure, Function, and Bioinformatics 70 (4), 1488-1497, 2008 | 79 | 2008 |
Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients Y Chu, N Elrod, C Wang, L Li, T Chen, A Routh, Z Xia, W Li, EJ Wagner, ... Oncogene 38 (21), 4154-4168, 2019 | 68 | 2019 |
Poly (A)-ClickSeq: click-chemistry for next-generation 3΄-end sequencing without RNA enrichment or fragmentation A Routh, P Ji, E Jaworski, Z Xia, W Li, EJ Wagner Nucleic acids research 45 (12), e112-e112, 2017 | 67 | 2017 |
Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus E Jaworski, A Routh PLoS pathogens 13 (5), e1006365, 2017 | 67 | 2017 |
ClickSeq: fragmentation-free next-generation sequencing via click ligation of adaptors to stochastically terminated 3′-azido cDNAs A Routh, SR Head, P Ordoukhanian, JE Johnson Journal of molecular biology 427 (16), 2610-2616, 2015 | 67 | 2015 |
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge A Muruato, MN Vu, BA Johnson, ME Davis-Gardner, A Vanderheiden, ... PLoS biology 19 (11), e3001284, 2021 | 65 | 2021 |
Microbial interactions in the mosquito gut determine Serratia colonization and blood-feeding propensity EV Kozlova, S Hegde, CM Roundy, G Golovko, MA Saldaña, CE Hart, ... The ISME journal 15 (1), 93-108, 2021 | 51 | 2021 |