Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes–associated variants TJ Nicolson, EA Bellomo, N Wijesekara, MK Loder, JM Baldwin, ... Diabetes 58 (9), 2070-2083, 2009 | 450 | 2009 |
Regulation of ATP production by mitochondrial Ca2+ AI Tarasov, EJ Griffiths, GA Rutter Cell calcium 52 (1), 28-35, 2012 | 359 | 2012 |
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells E Haythorne, M Rohm, M van de Bunt, MF Brereton, AI Tarasov, ... Nature communications 10 (1), 2474, 2019 | 285 | 2019 |
TCF7L2 regulates late events in insulin secretion from pancreatic islet β-cells G da Silva Xavier, MK Loder, A McDonald, AI Tarasov, R Carzaniga, ... Diabetes 58 (4), 894-905, 2009 | 278 | 2009 |
Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes Q Zhang, R Ramracheya, C Lahmann, A Tarasov, M Bengtsson, O Braha, ... Cell metabolism 18 (6), 871-882, 2013 | 255 | 2013 |
Metabolic Regulation of the Pancreatic Beta-Cell ATP-Sensitive K+ Channel: A Pas de Deux A Tarasov, J Dusonchet, F Ashcroft Diabetes 53 (suppl_3), S113-S122, 2004 | 203 | 2004 |
The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells AI Tarasov, F Semplici, MA Ravier, EA Bellomo, TJ Pullen, P Gilon, ... PloS one 7 (7), e39722, 2012 | 198 | 2012 |
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation M Shigeto, R Ramracheya, AI Tarasov, CY Cha, MV Chibalina, B Hastoy, ... The Journal of clinical investigation 125 (12), 4714-4728, 2015 | 178 | 2015 |
Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum … G Meur, A Simon, N Harun, M Virally, A Dechaume, A Bonnefond, S Fetita, ... Diabetes 59 (3), 653-661, 2010 | 174 | 2010 |
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion E Vergari, JG Knudsen, R Ramracheya, A Salehi, Q Zhang, J Adam, ... Nature communications 10 (1), 139, 2019 | 164 | 2019 |
Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR) D Li, S Chen, EA Bellomo, AI Tarasov, C Kaut, GA Rutter, W Li Proceedings of the National Academy of Sciences 108 (52), 21063-21068, 2011 | 160 | 2011 |
Sulfonylurea improves CNS function in a case of intermediate DEND syndrome caused by a mutation in KCNJ11 W Mlynarski, AI Tarasov, A Gach, CA Girard, I Pietrzak, L Zubcevic, ... Nature clinical practice Neurology 3 (11), 640-645, 2007 | 132 | 2007 |
Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane CS Olofsson, S Collins, M Bengtsson, L Eliasson, A Salehi, K Shimomura, ... Diabetes 56 (7), 1888-1897, 2007 | 116 | 2007 |
Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo G Sun, AI Tarasov, J McGinty, A McDonald, G da Silva Xavier, T Gorman, ... Diabetologia 53, 924-936, 2010 | 113 | 2010 |
Frequency-dependent mitochondrial Ca2+ accumulation regulates ATP synthesis in pancreatic β cells AI Tarasov, F Semplici, D Li, R Rizzuto, MA Ravier, P Gilon, GA Rutter Pflügers Archiv-European Journal of Physiology 465, 543-554, 2013 | 93 | 2013 |
Adrenaline stimulates glucagon secretion by Tpc2-dependent Ca2+ mobilization from acidic stores in pancreatic α-cells A Hamilton, Q Zhang, A Salehi, M Willems, JG Knudsen, AK Ringgaard, ... Diabetes 67 (6), 1128-1139, 2018 | 92 | 2018 |
Identification of the PIP2‐binding site on Kir6. 2 by molecular modelling and functional analysis S Haider, AI Tarasov, TJ Craig, MSP Sansom, FM Ashcroft The EMBO journal 26 (16), 3749-3759, 2007 | 92 | 2007 |
α-cell glucokinase suppresses glucose-regulated glucagon secretion D Basco, Q Zhang, A Salehi, A Tarasov, W Dolci, P Herrera, I Spiliotis, ... Nature communications 9 (1), 546, 2018 | 83 | 2018 |
A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and β-cell glucose sensing is associated with type 2 diabetes in adults AI Tarasov, TJ Nicolson, JP Riveline, TK Taneja, SA Baldwin, JM Baldwin, ... Diabetes 57 (6), 1595-1604, 2008 | 81 | 2008 |
LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo G Sun, AI Tarasov, JA McGinty, PM French, A McDonald, I Leclerc, ... American Journal of Physiology-Endocrinology and Metabolism 298 (6), E1261-E1273, 2010 | 77 | 2010 |