Hijacking SARS-CoV-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on the receptor binding domain A Carino, F Moraca, B Fiorillo, S Marchianò, V Sepe, M Biagioli, ... Frontiers in Chemistry 8, 572885, 2020 | 103 | 2020 |
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands C Festa, B Renga, C D’Amore, V Sepe, C Finamore, S De Marino, ... Journal of medicinal chemistry 57 (20), 8477-8495, 2014 | 87 | 2014 |
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists V Sepe, C Festa, B Renga, A Carino, S Cipriani, C Finamore, D Masullo, ... Scientific reports 6 (1), 19008, 2016 | 50 | 2016 |
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists S De Marino, A Carino, D Masullo, C Finamore, S Marchianò, S Cipriani, ... Scientific Reports 7 (1), 43290, 2017 | 41 | 2017 |
Investigation around the oxadiazole core in the discovery of a new chemotype of potent and selective FXR antagonists C Festa, C Finamore, S Marchianò, FS Di Leva, A Carino, MC Monti, ... ACS Medicinal Chemistry Letters 10 (4), 504-510, 2019 | 31 | 2019 |
Novel isoxazole derivatives with potent FXR agonistic activity prevent acetaminophen-induced liver injury V Sepe, S Marchianò, C Finamore, G Baronissi, FS Di Leva, A Carino, ... ACS Medicinal Chemistry Letters 10 (4), 407-412, 2018 | 29 | 2018 |
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X … V Sepe, B Renga, C Festa, C Finamore, D Masullo, A Carino, S Cipriani, ... Steroids 105, 59-67, 2016 | 22 | 2016 |
Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside SM Goldansaz, C Festa, E Pagano, S De Marino, C Finamore, OA Parisi, ... Molecules 24 (9), 1684, 2019 | 19 | 2019 |
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative … S De Vita, C Finamore, MG Chini, G Saviano, V De Felice, S De Marino, ... Plants 11 (13), 1671, 2022 | 18 | 2022 |
Discovery of ((1, 2, 4-oxadiazol-5-yl) pyrrolidin-3-yl) ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1 FS Di Leva, C Festa, A Carino, S De Marino, S Marchianò, D Di Marino, ... Scientific reports 9 (1), 2504, 2019 | 17 | 2019 |
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands C Finamore, C Festa, B Renga, V Sepe, A Carino, D Masullo, M Biagioli, ... Scientific reports 6 (1), 29320, 2016 | 16 | 2016 |
Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116 F Cattaneo, S De Marino, M Parisi, C Festa, M Castaldo, C Finamore, ... Phytochemical Analysis 30 (5), 524-534, 2019 | 13 | 2019 |
GPBAR1 activation by C6-substituted hyodeoxycholane analogues protect against colitis SD Marino, C Finamore, M Biagioli, A Carino, S Marchianò, R Roselli, ... ACS Medicinal Chemistry Letters 11 (5), 818-824, 2020 | 11 | 2020 |
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests S De Vita, MG Chini, G Saviano, C Finamore, C Festa, G Lauro, ... Biomolecules 11 (10), 1490, 2021 | 7 | 2021 |
Homoallylic o-halobenzylamines: asymmetric diversity-oriented synthesis of benzo-fused cyclic amines R Lázaro, P Barrio, C Finamore, R Román, S Fustero Structural Chemistry 28, 445-452, 2017 | 6 | 2017 |
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain. Front Chem. 2020; 8 … A Carino, F Moraca, B Fiorillo, S Marchiano, V Sepe, M Biagioli, ... DOI: https://doi. org/10.3389/fchem, 572885, 2020 | 5 | 2020 |
Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists S De Marino, A Carino, D Masullo, C Finamore, V Sepe, S Marchianò, ... RSC advances 7 (52), 32877-32885, 2017 | 5 | 2017 |
Discovery of a novel class of dual GPBAR1 agonists–RORγt inverse agonists for the treatment of IL-17-mediated disorders B Fiorillo, R Roselli, C Finamore, M Biagioli, C Di Giorgio, M Bordoni, ... ACS omega 8 (6), 5983-5994, 2023 | 4 | 2023 |
Introduction of nonacidic side chains on 6-ethylcholane scaffolds in the identification of potent bile acid receptor agonists with improved pharmacokinetic properties C Finamore, G Baronissi, S Marchianò, FS Di Leva, A Carino, MC Monti, ... Molecules 24 (6), 1043, 2019 | 4 | 2019 |
Expanding the library of 1, 2, 4-oxadiazole derivatives: discovery of new farnesoid X receptor (FXR) antagonists/pregnane X receptor (PXR) agonists C Finamore, C Festa, B Fiorillo, FSD Leva, R Roselli, S Marchianò, ... Molecules 28 (6), 2840, 2023 | 2 | 2023 |