CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation V Narendra, PP Rocha, D An, R Raviram, JA Skok, EO Mazzoni, ... Science 347 (6225), 1017-1021, 2015 | 604 | 2015 |
Capturing the onset of PRC2-mediated repressive domain formation O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ... Molecular cell 70 (6), 1149-1162. e5, 2018 | 240 | 2018 |
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling PP Rocha, M Scholze, W Bleiß, H Schrewe Development 137 (16), 2723-2731, 2010 | 173 | 2010 |
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms J Mullenders, B Aranda-Orgilles, P Lhoumaud, M Keller, J Pae, K Wang, ... Journal of Experimental Medicine 212 (11), 1833-1850, 2015 | 169 | 2015 |
CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci Y Fu, PP Rocha, VM Luo, R Raviram, Y Deng, EO Mazzoni, JA Skok Nature communications 7 (1), 11707, 2016 | 156 | 2016 |
MED12 regulates HSC-specific enhancers independently of mediator kinase activity to control hematopoiesis B Aranda-Orgilles, R Saldaña-Meyer, E Wang, E Trompouki, A Fassl, ... Cell stem cell 19 (6), 784-799, 2016 | 116 | 2016 |
Low-grade astrocytoma mutations in IDH1, P53, and ATRX cooperate to block differentiation of human neural stem cells via repression of SOX2 AS Modrek, D Golub, T Khan, D Bready, J Prado, C Bowman, J Deng, ... Cell reports 21 (5), 1267-1280, 2017 | 99 | 2017 |
4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments JAS Ramya Raviram, Pedro P. Rocha, Christian L. Müller, Emily R. Miraldi ... Plos Computational Biology, 2016 | 92 | 2016 |
Close proximity to Igh is a contributing factor to AID-mediated translocations PP Rocha, M Micsinai, JHR Kim, SL Hewitt, PP Souza, T Trimarchi, ... Molecular cell 47 (6), 873-885, 2012 | 70 | 2012 |
Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers P Veliça, NJ Davies, PP Rocha, H Schrewe, JP Ride, CM Bunce Molecular cancer 8, 1-12, 2009 | 70 | 2009 |
Breaking TADs: insights into hierarchical genome organization PP Rocha, R Raviram, R Bonneau, JA Skok Epigenomics 7 (4), 523-526, 2015 | 62 | 2015 |
Enhancer–promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness S Chakraborty, N Kopitchinski, Z Zuo, A Eraso, P Awasthi, R Chari, A Mitra, ... Nature genetics 55 (2), 280-290, 2023 | 60* | 2023 |
Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions T Jiang, R Raviram, V Snetkova, PP Rocha, C Proudhon, S Badri, ... Nucleic acids research 44 (18), 8714-8725, 2016 | 52 | 2016 |
Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate R Raviram, PP Rocha, VM Luo, E Swanzey, ER Miraldi, EB Chuong, ... Genome biology 19, 1-19, 2018 | 44 | 2018 |
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination AS Thomas-Claudepierre, I Robert, PP Rocha, R Raviram, E Schiavo, ... Journal of Experimental Medicine 213 (3), 303-312, 2016 | 38 | 2016 |
A damage-independent role for 53BP1 that impacts break order and Igh architecture during class switch recombination PP Rocha, R Raviram, Y Fu, JH Kim, VM Luo, A Aljoufi, E Swanzey, ... Cell reports 16 (1), 48-55, 2016 | 37 | 2016 |
Wolf-Hirschhorn syndrome candidate 1 is necessary for correct hematopoietic and B cell development E Campos-Sanchez, N Deleyto-Seldas, V Dominguez, ... Cell reports 19 (8), 1586-1601, 2017 | 35 | 2017 |
GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia L Belver, AY Yang, R Albero, D Herranz, FG Brundu, SA Quinn, ... Cancer discovery 9 (12), 1774-1791, 2019 | 34 | 2019 |
Alu insertion variants alter gene transcript levels LM Payer, JP Steranka, MS Kryatova, G Grillo, M Lupien, PP Rocha, ... Genome research 31 (12), 2236-2248, 2021 | 30 | 2021 |
Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function S Erdogmus, AR Concepcion, M Yamashita, I Sidhu, AY Tao, W Li, ... Nature communications 13 (1), 2033, 2022 | 28 | 2022 |