Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest FM Jault, JM Jault, F Ruchti, EA Fortunato, C Clark, J Corbeil, ... Journal of virology 69 (11), 6697-6704, 1995 | 374 | 1995 |
Cell cycle dysregulation by human cytomegalovirus: influence of the cell cycle phase at the time of infection and effects on cyclin transcription BS Salvant, EA Fortunato, DH Spector Journal of virology 72 (5), 3729-3741, 1998 | 249 | 1998 |
Exploitation of cellular signaling and regulatory pathways by human cytomegalovirus EA Fortunato, AK McElroy, V Sanchez, DH Spector Trends in microbiology 8 (3), 111-119, 2000 | 196 | 2000 |
p53 and RPA are sequestered in viral replication centers in the nuclei of cells infected with human cytomegalovirus EA Fortunato, DH Spector Journal of virology 72 (3), 2033-2039, 1998 | 154 | 1998 |
Human cytomegalovirus disrupts both ataxia telangiectasia mutated protein (ATM)-and ATM-Rad3-related kinase-mediated DNA damage responses during lytic infection MH Luo, K Rosenke, K Czornak, EA Fortunato Journal of virology 81 (4), 1934-1950, 2007 | 128 | 2007 |
Specific chromosome 1 breaks induced by human cytomegalovirus EA Fortunato, ML Dell'Aquila, DH Spector Proceedings of the National Academy of Sciences 97 (2), 853-858, 2000 | 128 | 2000 |
Regulation of human cytomegalovirus gene expression EA Fortunato, DH Spector Advances in virus research 54, 61-128, 1999 | 123 | 1999 |
Human cytomegalovirus infection causes premature and abnormal differentiation of human neural progenitor cells MH Luo, H Hannemann, AS Kulkarni, PH Schwartz, JM O'Dowd, ... Journal of virology 84 (7), 3528-3541, 2010 | 122 | 2010 |
Neonatal neural progenitor cells and their neuronal and glial cell derivatives are fully permissive for human cytomegalovirus infection MH Luo, PH Schwartz, EA Fortunato Journal of virology 82 (20), 9994-10007, 2008 | 119 | 2008 |
Potential role for p53 in the permissive life cycle of human cytomegalovirus NC Casavant, MH Luo, K Rosenke, T Winegardner, A Zurawska, ... Journal of virology 80 (17), 8390-8401, 2006 | 113 | 2006 |
Infection of cells with human cytomegalovirus during S phase results in a blockade to immediate-early gene expression that can be overcome by inhibition of the proteasome EA Fortunato, V Sanchez, JY Yen, DH Spector Journal of virology 76 (11), 5369-5379, 2002 | 96 | 2002 |
Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional … EA Fortunato, MH Sommer, K Yoder, DH Spector Journal of virology 71 (11), 8176-8185, 1997 | 85 | 1997 |
Viral induction of site‐specific chromosome damage EA Fortunato, DH Spector Reviews in medical virology 13 (1), 21-37, 2003 | 84 | 2003 |
Human cytomegalovirus compromises development of cerebral organoids RM Brown, PSJB Rana, HK Jaeger, JM O’Dowd, OB Balemba, ... Journal of virology 93 (17), 10.1128/jvi. 00957-19, 2019 | 62 | 2019 |
Long-term infection and shedding of human cytomegalovirus in T98G glioblastoma cells MH Luo, EA Fortunato Journal of virology 81 (19), 10424-10436, 2007 | 57 | 2007 |
Human cytomegalovirus (HCMV) and hearing impairment: infection of fibroblast cells with HCMV induces chromosome breaks at 1q23. 3, between loci DFNA7 and DFNA49—both involved … M Nystad, T Fagerheim, V Brox, EA Fortunato, Ø Nilssen Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 637 (1 …, 2008 | 41 | 2008 |
HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome JM O'Dowd, AG Zavala, CJ Brown, T Mori, EA Fortunato PLoS pathogens 8 (11), e1003038, 2012 | 34 | 2012 |
The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfection H Hannemann, K Rosenke, JM O'Dowd, EA Fortunato Journal of virology 83 (9), 4316-4325, 2009 | 34 | 2009 |
Bromodeoxyuridine-labeled viral particles as a tool for visualization of the immediate-early events of human cytomegalovirus infection K Rosenke, EA Fortunato Journal of virology 78 (14), 7818-7822, 2004 | 34 | 2004 |
An intact sequence-specific DNA-binding domain is required for human cytomegalovirus-mediated sequestration of p53 and may promote in vivo binding to the viral genome during … K Rosenke, MA Samuel, ET McDowell, MA Toerne, EA Fortunato Virology 348 (1), 19-34, 2006 | 28 | 2006 |