| The direct binding of insulin-like growth factor-1 (IGF-1) to integrin αvβ3 is involved in IGF-1 signaling J Saegusa, S Yamaji, K Ieguchi, CY Wu, KS Lam, FT Liu, YK Takada, ... Journal of Biological Chemistry 284 (36), 24106-24114, 2009 | 106 | 2009 |
| Direct binding of the EGF-like domain of neuregulin-1 to integrins (αvβ3 and α6β4) is involved in neuregulin-1/ErbB signaling K Ieguchi, M Fujita, Z Ma, P Davari, Y Taniguchi, K Sekiguchi, B Wang, ... Journal of Biological Chemistry 285 (41), 31388-31398, 2010 | 100 | 2010 |
| ADAM12-cleaved ephrin-A1 contributes to lung metastasis K Ieguchi, T Tomita, T Omori, A Komatsu, A Deguchi, J Masuda, SL Duffy, ... Oncogene 33 (17), 2179-2190, 2014 | 87 | 2014 |
| Roles of EphA1/A2 and ephrin‐A1 in cancer K Ieguchi, Y Maru Cancer science 110 (3), 841-848, 2019 | 70 | 2019 |
| Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation … M Fujita, K Ieguchi, P Davari, S Yamaji, Y Taniguchi, K Sekiguchi, ... Journal of Biological Chemistry 287 (15), 12491-12500, 2012 | 67 | 2012 |
| An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses … M Fujita, K Ieguchi, DM Cedano-Prieto, A Fong, C Wilkerson, JQ Chen, ... Journal of Biological Chemistry 288 (27), 19593-19603, 2013 | 47 | 2013 |
| A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist S Yamaji, J Saegusa, K Ieguchi, M Fujita, S Mori, YK Takada, Y Takada PloS one 5 (4), e10273, 2010 | 37 | 2010 |
| Human serum amyloid A3 (SAA3) protein, expressed as a fusion protein with SAA2, binds the oxidized low density lipoprotein receptor T Tomita, K Ieguchi, T Sawamura, Y Maru PloS one 10 (3), e0118835, 2015 | 32 | 2015 |
| LINGO-1 protein interacts with the p75 neurotrophin receptor in intracellular membrane compartments JS Meabon, R De Laat, K Ieguchi, JC Wiley, MP Hudson, M Bothwell Journal of Biological Chemistry 290 (15), 9511-9520, 2015 | 30 | 2015 |
| Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1 K Ieguchi, S Ueda, T Kataoka, T Satoh Journal of Biological Chemistry 282 (32), 23296-23305, 2007 | 29 | 2007 |
| Increased plasma soluble PD-1 concentration correlates with disease progression in patients with cancer treated with anti-PD-1 antibodies R Ohkuma, K Ieguchi, M Watanabe, D Takayanagi, T Goshima, R Onoue, ... Biomedicines 9 (12), 1929, 2021 | 24 | 2021 |
| Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling JS Meabon, R de Laat, K Ieguchi, D Serbzhinsky, MP Hudson, BR Huber, ... Molecular and Cellular Neuroscience 70, 1-10, 2016 | 24 | 2016 |
| Eph as a target in inflammation K Ieguchi Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug …, 2015 | 23 | 2015 |
| Ephrin-A1 expression induced by S100A8 is mediated by the toll-like receptor 4 K Ieguchi, T Omori, A Komatsu, T Tomita, A Deguchi, Y Maru Biochemical and biophysical research communications 440 (4), 623-629, 2013 | 21 | 2013 |
| ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor T Tomita, K Ieguchi, F Coin, Y Kato, H Kikuchi, Y Oshima, S Kurata, ... PloS one 9 (9), e108957, 2014 | 15 | 2014 |
| Savior or not: ADAM17 inhibitors overcome radiotherapy-resistance in non-small cell lung cancer K Ieguchi, Y Maru Journal of thoracic disease 8 (8), E813, 2016 | 14 | 2016 |
| Analysis of adam12-mediated ephrin-a1 cleavage and its biological functions K Ieguchi, T Tomita, T Takao, T Omori, T Mishima, I Shimizu, M Tognolini, ... International Journal of Molecular Sciences 22 (5), 2480, 2021 | 13 | 2021 |
| The sympathetic nervous system contributes to the establishment of pre-metastatic pulmonary microenvironments K Ieguchi, M Funakoshi, T Mishima, K Takizawa, T Omori, F Nakamura, ... International Journal of Molecular Sciences 23 (18), 10652, 2022 | 8 | 2022 |
| Drug targeting based on a new concept-targeting against TLR4 as an example Y Maru, T Tomita, A Deguchi, K Ieguchi, M Takita, F Tsukahara, ... Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug …, 2015 | 8 | 2015 |
| Cross-talk between integrin 64 and insulin-like growth factor-1 receptor (IGF1R) through direct 64 binding to IGF1 and subsequent 64-IGF1-IGF1R ternary complex formation in … M Fujita, K Ieguchi, P Davari, S Yamaji, Y Taniguchi, K Sekiguchi, ... J. Biol. Chem 287, 12491-12500, 2012 | 8 | 2012 |
