Dendrimers and miktoarm polymers based multivalent nanocarriers for efficient and targeted drug delivery GM Soliman, A Sharma, D Maysinger, A Kakkar Chemical communications 47 (34), 9572-9587, 2011 | 145 | 2011 |
Targeting mitochondrial dysfunction and oxidative stress in activated microglia using dendrimer-based therapeutics A Sharma, K Liaw, R Sharma, Z Zhang, S Kannan, RM Kannan Theranostics 8 (20), 5529, 2018 | 130 | 2018 |
Design and evaluation of multifunctional nanocarriers for selective delivery of coenzyme Q10 to mitochondria A Sharma, GM Soliman, N Al-Hajaj, R Sharma, D Maysinger, A Kakkar Biomacromolecules 13 (1), 239-252, 2012 | 116 | 2012 |
Activated microglia targeting dendrimer–minocycline conjugate as therapeutics for neuroinflammation R Sharma, SY Kim, A Sharma, Z Zhang, SP Kambhampati, S Kannan, ... Bioconjugate chemistry 28 (11), 2874-2886, 2017 | 95 | 2017 |
Effect of mannose targeting of hydroxyl PAMAM dendrimers on cellular and organ biodistribution in a neonatal brain injury model A Sharma, JE Porterfield, E Smith, R Sharma, S Kannan, RM Kannan Journal of Controlled Release 283, 175-189, 2018 | 92 | 2018 |
Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury R Sharma, SP Kambhampati, Z Zhang, A Sharma, S Chen, EI Duh, ... Journal of Controlled Release 323, 361-375, 2020 | 88 | 2020 |
Designing Dendrimer and Miktoarm Polymer Based Multi-Tasking Nanocarriers for Efficient Medical Therapy A Sharma, A Kakkar Molecules 20 (9), 16987-17015, 2015 | 70 | 2015 |
Dense hydroxyl polyethylene glycol dendrimer targets activated glia in multiple CNS disorders A Sharma, R Sharma, Z Zhang, K Liaw, SP Kambhampati, JE Porterfield, ... Science Advances 6 (4), eaay8514, 2020 | 55 | 2020 |
Scalable Synthesis and Validation of PAMAM Dendrimer-N-acetyl cysteine Conjugate for Potential Translation RSASSPKRRRZZJLCSKRM Kannan Bioengineering & Translational Medicine, 2018 | 55 | 2018 |
Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma R Sharma, K Liaw, A Sharma, A Jimenez, M Chang, S Salazar, I Amlani, ... Journal of Controlled Release 337, 179-192, 2021 | 53 | 2021 |
“Click” dendrimers as anti-inflammatory agents: with insights into their binding from molecular modeling studies K Neibert, V Gosein, A Sharma, M Khan, MA Whitehead, D Maysinger, ... Molecular Pharmaceutics 10 (6), 2502-2508, 2013 | 47 | 2013 |
Multivalent niacin nanoconjugates for delivery to cytoplasmic lipid droplets A Sharma, A Khatchadourian, K Khanna, R Sharma, A Kakkar, ... Biomaterials 32 (5), 1419-1429, 2011 | 42 | 2011 |
Dendrimer-mediated targeted delivery of rapamycin to tumor-associated macrophages improves systemic treatment of glioblastoma A Sharma, K Liaw, R Sharma, T Spriggs, S Appiani La Rosa, S Kannan, ... Biomacromolecules 21 (12), 5148-5161, 2020 | 39 | 2020 |
Facile construction of multifunctional nanocarriers using sequential click chemistry for applications in biology A Sharma, K Neibert, R Sharma, R Hourani, D Maysinger, A Kakkar Macromolecules 44 (3), 521-529, 2011 | 36 | 2011 |
Systemic dendrimer delivery of triptolide to tumor-associated macrophages improves anti-tumor efficacy and reduces systemic toxicity in glioblastoma K Liaw, R Sharma, A Sharma, S Salazar, SA La Rosa, RM Kannan Journal of Controlled Release 329, 434-444, 2021 | 26 | 2021 |
Neuroprotective effects of a dendrimer-based glutamate carboxypeptidase inhibitor on superoxide dismutase transgenic mice after neonatal hypoxic-ischemic brain injury OA Cabeza, Z Zhang, ES Khoury, RA Sheldon, A Sharma, F Zhang, ... Neurobiology of disease 148, 105201, 2021 | 25 | 2021 |
Targeting mitochondria in tumor-associated macrophages using a dendrimer-conjugated TSPO ligand that stimulates antitumor signaling in glioblastoma A Sharma, K Liaw, R Sharma, AG Thomas, BS Slusher, S Kannan, ... Biomacromolecules 21 (9), 3909-3922, 2020 | 25 | 2020 |
Combined A3 coupling and click chemistry approach for the synthesis of dendrimer based biological tools. A Sharma, D Mejía, A Regnaud, N Uhlig, CJ Li, D Maysinger, A Kakkar ACS Macro Letters 3 (10), 1079-1083, 2014 | 25 | 2014 |
Design and synthesis of multifunctional traceable dendrimers for visualizing drug delivery A Sharma, D Mejía, D Maysinger, A Kakkar RSC Advances 4, 19242-19245, 2014 | 25 | 2014 |
Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity S Datta, M Cano, G Satyanarayana, T Liu, L Wang, J Wang, J Cheng, ... Autophagy 19 (3), 966-983, 2023 | 24 | 2023 |