Best practices and benchmarks for intact protein analysis for top-down mass spectrometry DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli, LF Schachner, Z Lin, ... Nature methods 16 (7), 587-594, 2019 | 340 | 2019 |
Top-down proteomics: ready for prime time? B Chen, KA Brown, Z Lin, Y Ge Analytical chemistry 90 (1), 110-127, 2017 | 204 | 2017 |
Top-down proteomics of large proteins up to 223 kDa enabled by serial size exclusion chromatography strategy W Cai, T Tucholski, B Chen, AJ Alpert, S McIlwain, T Kohmoto, S Jin, Y Ge Analytical chemistry 89 (10), 5467-5475, 2017 | 132 | 2017 |
Online hydrophobic interaction chromatography–mass spectrometry for top-down proteomics B Chen, Y Peng, SG Valeja, L Xiu, AJ Alpert, Y Ge Analytical chemistry 88 (3), 1885-1891, 2016 | 115 | 2016 |
A photocleavable surfactant for top-down proteomics KA Brown, B Chen, TM Guardado-Alvarez, Z Lin, L Hwang, S Ayaz-Guner, ... Nature methods 16 (5), 417-420, 2019 | 91 | 2019 |
Online hydrophobic interaction chromatography–mass spectrometry for the analysis of intact monoclonal antibodies B Chen, Z Lin, AJ Alpert, C Fu, Q Zhang, WA Pritts, Y Ge Analytical chemistry 90 (12), 7135-7138, 2018 | 84 | 2018 |
Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum TN Tiambeng, DS Roberts, KA Brown, Y Zhu, B Chen, Z Wu, SD Mitchell, ... Nature Communications 11 (1), 3903, 2020 | 56 | 2020 |
Coupling functionalized cobalt ferrite nanoparticle enrichment with online LC/MS/MS for top-down phosphoproteomics B Chen, L Hwang, W Ochowicz, Z Lin, TM Guardado-Alvarez, W Cai, ... Chemical science 8 (6), 4306-4311, 2017 | 43 | 2017 |
A top-down proteomics platform coupling serial size exclusion chromatography and Fourier transform ion cyclotron resonance mass spectrometry T Tucholski, SJ Knott, B Chen, P Pistono, Z Lin, Y Ge Analytical chemistry 91 (6), 3835-3844, 2019 | 42 | 2019 |
Middle-down multi-attribute analysis of antibody-drug conjugates with electron transfer dissociation B Chen, Z Lin, Y Zhu, Y Jin, E Larson, Q Xu, C Fu, Z Zhang, Q Zhang, ... Analytical chemistry 91 (18), 11661-11669, 2019 | 29 | 2019 |
Reproducible large-scale synthesis of surface silanized nanoparticles as an enabling nanoproteomics platform: enrichment of the human heart phosphoproteome DS Roberts, B Chen, TN Tiambeng, Z Wu, Y Ge, S Jin Nano research 12, 1473-1481, 2019 | 29 | 2019 |
Impact of phosphorylation on the mass spectrometry quantification of intact phosphoproteins Z Wu, TN Tiambeng, W Cai, B Chen, Z Lin, ZR Gregorich, Y Ge Analytical chemistry 90 (8), 4935-4939, 2018 | 27 | 2018 |
Top-down mass spectrometry of synthetic single guide ribonucleic acids enabled by facile sample clean-up CM Crittenden, MB Lanzillotti, B Chen Analytical Chemistry 95 (6), 3180-3186, 2023 | 17 | 2023 |
Development of an ion pairing reversed-phase liquid chromatography-mass spectrometry method for characterization of clustered regularly interspaced short palindromic repeats … B Wei, J Wang, L Cadang, A Goyon, B Chen, F Yang, K Zhang Journal of Chromatography A 1665, 462839, 2022 | 14 | 2022 |
Comprehensive characterization of the recombinant catalytic subunit of cAMP-dependent protein kinase by top-down mass spectrometry Z Wu, Y Jin, B Chen, MK Gugger, CL Wilkinson-Johnson, TN Tiambeng, ... Journal of The American Society for Mass Spectrometry 30 (12), 2561-2570, 2019 | 14 | 2019 |
Rapid analysis of reduced antibody drug conjugate by online LC-MS/MS with fourier transform Ion cyclotron resonance mass spectrometry EJ Larson, Y Zhu, Z Wu, B Chen, Z Zhang, S Zhou, L Han, Q Zhang, Y Ge Analytical chemistry 92 (22), 15096-15103, 2020 | 12 | 2020 |
The impact of phosphorylation on electron capture dissociation of proteins: a top-down perspective B Chen, X Guo, T Tucholski, Z Lin, S McIlwain, Y Ge Journal of the American Society for Mass Spectrometry 28 (9), 1805-1814, 2017 | 12 | 2017 |
Characterization of high molecular weight multi-arm functionalized PEG–maleimide for protein conjugation by charge-reduction mass spectrometry coupled to two-dimensional liquid … SH Yang, B Chen, J Wang, K Zhang Analytical Chemistry 92 (12), 8584-8590, 2020 | 9 | 2020 |
Stable picodisc assemblies from saposin proteins and branched detergents KW Kurgan, B Chen, KA Brown, P Falco Cobra, X Ye, Y Ge, SH Gellman Biochemistry 60 (14), 1108-1119, 2021 | 3 | 2021 |
Ultraviolet photodissociation facilitates mass spectrometry-based structure elucidation with pyrrolidine and piperidine containing compounds B Chen, KL Kurita, N Wong, CM Crittenden Journal of Pharmaceutical and Biomedical Analysis 211, 114622, 2022 | 2 | 2022 |