Fatty acids and NLRP3 inflammasome–mediated inflammation in metabolic tissues JC Ralston, CL Lyons, EB Kennedy, AM Kirwan, HM Roche Annual review of nutrition 37 (1), 77-102, 2017 | 197 | 2017 |
Polyunsaturated fatty acid regulation of adipocyte FADS1 and FADS2 expression and function JC Ralston, S Matravadia, N Gaudio, GP Holloway, DM Mutch Obesity 23 (4), 725-728, 2015 | 87 | 2015 |
Inhibition of stearoyl-CoA desaturase-1 in differentiating 3T3-L1 preadipocytes upregulates elongase 6 and downregulates genes affecting triacylglycerol synthesis JC Ralston, F Badoud, B Cattrysse, PD McNicholas, DM Mutch International journal of obesity 38 (11), 1449-1456, 2014 | 65 | 2014 |
Individual saturated and monounsaturated fatty acids trigger distinct transcriptional networks in differentiated 3T3-L1 preadipocytes B Shaw, S Lambert, MHT Wong, JC Ralston, C Stryjecki, DM Mutch Lifestyle Genomics 6 (1), 1-15, 2013 | 56 | 2013 |
Variation in the FADS1/2 gene cluster alters plasma n− 6 PUFA and is weakly associated with hsCRP levels in healthy young adults K Roke, JC Ralston, S Abdelmagid, DE Nielsen, A Badawi, A El-Sohemy, ... Prostaglandins, Leukotrienes and Essential Fatty Acids 89 (4), 257-263, 2013 | 47 | 2013 |
Hepatic BSCL2 (Seipin) deficiency disrupts lipid droplet homeostasis and increases lipid metabolism via SCD1 activity MA Lounis, S Lalonde, SA Rial, KF Bergeron, JC Ralston, DM Mutch, ... Lipids 52, 129-150, 2017 | 33 | 2017 |
SCD1 mediates the influence of exogenous saturated and monounsaturated fatty acids in adipocytes: effects on cellular stress, inflammatory markers and fatty acid elongation JC Ralston, AH Metherel, KD Stark, DM Mutch The Journal of nutritional biochemistry 27, 241-248, 2016 | 28 | 2016 |
SCD1 inhibition during 3T3-L1 adipocyte differentiation remodels triacylglycerol, diacylglycerol and phospholipid fatty acid composition JC Ralston, DM Mutch Prostaglandins, Leukotrienes and Essential Fatty Acids 98, 29-37, 2015 | 27 | 2015 |
Ethnic-and sex-specific associations between plasma fatty acids and markers of insulin resistance in healthy young adults JC Ralston, MA Zulyniak, DE Nielsen, S Clarke, A Badawi, A El-Sohemy, ... Nutrition & metabolism 10, 1-9, 2013 | 25 | 2013 |
Vaccenic acid in serum triglycerides is associated with markers of insulin resistance in men MA Zulyniak, JC Ralston, AJ Tucker, KA MacKay, LM Hillyer, ... Applied Physiology, Nutrition, and Metabolism 37 (5), 1003-1007, 2012 | 13 | 2012 |
Dietary substitution of SFA with MUFA within high-fat diets attenuates hyperinsulinaemia and pancreatic islet dysfunction JC Ralston, MS Nguyen-Tu, CL Lyons, AA Cooke, AM Murphy, A Falvey, ... British Journal of Nutrition 124 (3), 247-255, 2020 | 12 | 2020 |
Nutritionally derived metabolic cues typical of the obese microenvironment increase cholesterol efflux capacity of adipose tissue macrophages ME O'Reilly, S Kajani, JC Ralston, YM Lenighan, HM Roche, ... Molecular nutrition & food research 63 (2), 1800713, 2019 | 11 | 2019 |
North American ginseng influences adipocyte–macrophage crosstalk regulation of inflammatory gene expression J Garbett, SAF Wilson, JC Ralston, AA De Boer, EMK Lui, DC Wright, ... Journal of Ginseng Research 40 (2), 141-150, 2016 | 11 | 2016 |
Microbiome Transfer Partly Overrides Lack of IL‐1RI Signaling to Alter Hepatic but Not Adipose Tissue Phenotype and Lipid Handling Following a High‐Fat Diet Challenge JC Ralston, KAJ Mitchelson, GM Lynch, TTT Tran, H Wang, CR Strain, ... Molecular Nutrition & Food Research 65 (1), 2000202, 2021 | 6 | 2021 |
Dietary substitution of saturated with monounsaturated fatty acids within high-fat diets attenuates hyperinsulinemia and pancreatic islet dysfunction JC Ralston, CL Lyons, AA Cooke, M Aoife, A Falvey, OM Finucane, ... Br. J. Nutr, 1-22, 2020 | 2 | 2020 |
Pancreatic islet dysfunction is partially attenuated by replacement of dietary saturated fatty acids with monounsaturated fatty acids JC Ralston, MS Nguyen-Tu, CL Lyons, AM Murphy, AA Cooke, A Falvey, ... Proceedings of the Nutrition Society 76 (OCE3), E55, 2017 | 2 | 2017 |
SCD1 inhibition modifies fatty acid regulation of adipocyte inflammation and lipid content J Ralston, A Metherel, K Stark, D Mutch The FASEB Journal 29, 743.4, 2015 | 1 | 2015 |
Elucidating the roles of stearoyl-coa desaturase 1 in adipocyte fatty acid metabolism and cellular function J Ralston University of Guelph, 2015 | 1 | 2015 |
Microbiome transfer between IL-1RI-/-and wild-type mice during high or low-fat feeding alters metabolic tissue functionality but not glucose homeostasis. JC Ralston, KAJ Mitchelson, GM Lynch, TTT Tran, CR Strain, ... Proceedings of the Nutrition Society 79 (OCE2), E92, 2020 | | 2020 |
Diet–Gene Interactions: Perspectives in Insulin Resistance and Type 2 Diabetes JC Ralston, HM Roche Principles of Nutrigenetics and Nutrigenomics, 371-376, 2020 | | 2020 |