Recent and Rapid Emergence of W-Beijing Strains of Mycobacterium tuberculosis in Cape Town, South Africa D Cowley, D Govender, B February, M Wolfe, L Steyn, J Evans, ... Clinical infectious diseases 47 (10), 1252-1259, 2008 | 171 | 2008 |
The complex mechanism of antimycobacterial action of 5-fluorouracil V Singh, M Brecik, R Mukherjee, JC Evans, Z Svetlíková, J Blaško, ... Chemistry & biology 22 (1), 63-75, 2015 | 96 | 2015 |
Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis JC Evans, C Trujillo, Z Wang, H Eoh, S Ehrt, D Schnappinger, ... ACS infectious diseases 2 (12), 958-968, 2016 | 74 | 2016 |
Rapid genotypic assays to identify drug-resistant Mycobacterium tuberculosis in South Africa J Evans, MC Stead, MP Nicol, H Segal Journal of antimicrobial chemotherapy 63 (1), 11-16, 2009 | 60 | 2009 |
Novel multiplex allele-specific PCR assays for the detection of resistance to second-line drugs in Mycobacterium tuberculosis J Evans, H Segal Journal of antimicrobial chemotherapy 65 (5), 897-900, 2010 | 54 | 2010 |
The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis JC Evans, V Mizrahi Frontiers in microbiology 6, 812, 2015 | 51 | 2015 |
A Novel Insertion Sequence, ISPa26, in oprD of Pseudomonas aeruginosa Is Associated with Carbapenem Resistance JC Evans, H Segal Antimicrobial agents and chemotherapy 51 (10), 3776-3777, 2007 | 45 | 2007 |
Nucleotide metabolism and DNA replication DF Warner, JC Evans, V Mizrahi Molecular Genetics of Mycobacteria, 633-656, 2014 | 44 | 2014 |
Priming the tuberculosis drug pipeline: new antimycobacterial targets and agents JC Evans, V Mizrahi Current opinion in microbiology 45, 39-46, 2018 | 42 | 2018 |
Glutamine synthetase in tilapia gastrointestinal tract: zonation, cDNA and induction by cortisol TP Mommsen, ER Busby, KR Von Schalburg, JC Evans, HL Osachoff, ... Journal of Comparative Physiology B 173, 419-427, 2003 | 39 | 2003 |
The Influence of HIV on the Evolution of Mycobacterium tuberculosis AS Koch, D Brites, D Stucki, JC Evans, R Seldon, A Heekes, N Mulder, ... Molecular biology and evolution 34 (7), 1654-1668, 2017 | 31 | 2017 |
Identification of aminopyrimidine‐sulfonamides as potent modulators of Wag31‐mediated cell elongation in mycobacteria V Singh, N Dhar, J Pató, GS Kolly, J Korduláková, M Forbak, JC Evans, ... Molecular microbiology 103 (1), 13-25, 2017 | 25 | 2017 |
Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase Z Xu, W Yin, LK Martinelli, J Evans, J Chen, Y Yu, DJ Wilson, V Mizrahi, ... Bioorganic & medicinal chemistry 22 (5), 1726-1735, 2014 | 23 | 2014 |
Blocking bacterial naphthohydroquinone oxidation and ADP-ribosylation improves activity of rifamycins against Mycobacterium abscessus US Ganapathy, T Lan, P Krastel, M Lindman, MD Zimmerman, HP Ho, ... Antimicrobial agents and chemotherapy 65 (9), 10.1128/aac. 00978-21, 2021 | 17 | 2021 |
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site V Mendes, SR Green, JC Evans, J Hess, M Blaszczyk, C Spry, O Bryant, ... Nature communications 12 (1), 143, 2021 | 16 | 2021 |
Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference** J El Bakali, M Blaszczyk, JC Evans, JA Boland, WJ McCarthy, I Fathoni, ... Angewandte Chemie International Edition 62 (17), e202300221, 2023 | 8 | 2023 |
The myxobacterial antibiotic myxovalargin: biosynthesis, structural revision, total synthesis, and molecular characterization of ribosomal inhibition TO Koller, U Scheid, T Kösel, J Herrmann, D Krug, HIM Boshoff, ... Journal of the American Chemical Society 145 (2), 851-863, 2023 | 7 | 2023 |
Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity JC Evans, D Murugesan, JM Post, V Mendes, Z Wang, N Nahiyaan, ... ACS Infectious Diseases 7 (6), 1666-1679, 2021 | 7 | 2021 |
Validation of CoaBC as a bactericidal target in the coenzyme A pathway of Mycobacterium tuberculosis. ACS Infect Dis 2: 958–968 JC Evans, C Trujillo, Z Wang, H Eoh, S Ehrt, D Schnappinger, ... | 7 | 2016 |
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl) isoxazole-3-carboxamides: Hit–to–lead optimization and release of a novel antitubercular chemotype via … M Girardini, F Ferlenghi, G Annunziato, G Degiacomi, B Papotti, C Marchi, ... European journal of medicinal chemistry 245, 114916, 2023 | 6 | 2023 |