In pulmonary arterial hypertension, reduced BMPR2 promotes endothelial-to-mesenchymal transition via HMGA1 and its target slug RK Hopper, JRAJ Moonen, I Diebold, A Cao, CJ Rhodes, NF Tojais, ... Circulation 133 (18), 1783-1794, 2016 | 220 | 2016 |
BMPR2 Preserves Mitochondrial Function and DNA during Reoxygenation to Promote Endothelial Cell Survival and Reverse Pulmonary Hypertension I Diebold, JK Hennigs, K Miyagawa, CG Li, NP Nickel, M Kaschwich, ... Cell Metabolism 21 (4), 596-608, 2015 | 211 | 2015 |
Elafin reverses pulmonary hypertension via caveolin-1–dependent bone morphogenetic protein signaling NP Nickel, E Spiekerkoetter, M Gu, CG Li, H Li, M Kaschwich, I Diebold, ... American journal of respiratory and critical care medicine 191 (11), 1273-1286, 2015 | 144 | 2015 |
Vascular Endothelial Cells: Heterogeneity and Targeting Approaches JK Hennigs, C Matuszcak, M Trepel, J Körbelin Cells 10 (10), 2712, 2021 | 107 | 2021 |
Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1–Mediated Metabolic and Epigenetic Changes K Miyagawa, M Shi, PI Chen, JK Hennigs, Z Zhao, M Wang, CG Li, T Saito, ... Circulation research 124 (2), 211-224, 2019 | 99 | 2019 |
Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus U Raaz, IN Schellinger, E Chernogubova, C Warnecke, Y Kayama, ... Circulation research 117 (6), 513-524, 2015 | 96 | 2015 |
Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension? JK Hennigs, G Keller, HJ Baumann, F Honecker, S Kluge, C Bokemeyer, ... BMC pulmonary medicine 11 (1), 30, 2011 | 94 | 2011 |
RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension CJ Rhodes, H Im, A Cao, JK Hennigs, L Wang, S Sa, PI Chen, NP Nickel, ... American journal of respiratory and critical care medicine 192 (3), 356-366, 2015 | 89 | 2015 |
Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension PI Chen, A Cao, K Miyagawa, NF Tojais, JK Hennigs, CG Li, NM Sweeney, ... JCI insight 2 (2), 2017 | 83 | 2017 |
Fiber optic bronchoscopy in patients with acute hypoxemic respiratory failure requiring noninvasive ventilation-a feasibility study HJ Baumann, H Klose, M Simon, T Ghadban, SA Braune, JK Hennigs, ... Critical Care 15 (4), R179, 2011 | 72 | 2011 |
PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis CG Li, C Mahon, NM Sweeney, E Verschueren, V Kantamani, D Li, ... Cell reports 26 (5), 1333-1343. e7, 2019 | 69 | 2019 |
Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase A Klinke, E Berghausen, K Friedrichs, S Molz, D Lau, L Remane, M Berlin, ... JCI insight 3 (11), 2018 | 59 | 2018 |
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ... Circulation 136 (20), 1920-1935, 2017 | 56 | 2017 |
Low intensity, long-term outpatient rehabilitation in COPD: a randomised controlled trial HJ Baumann, S Kluge, K Rummel, H Klose, JK Hennigs, T Schmoller, ... Respiratory research 13 (1), 86, 2012 | 55 | 2012 |
Enhanced Caspase Activity Contributes to Aortic Wall Remodeling and Early Aneurysm Development in a Murine Model of Marfan Syndrome FC Emrich, H Okamura, AR Dalal, K Penov, DR Merk, U Raaz, ... Arteriosclerosis, thrombosis, and vascular biology 35 (1), 146-154, 2015 | 53 | 2015 |
PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ... Circulation Research 128 (3), 401-418, 2021 | 50 | 2021 |
The Endothelial ADMA/NO Pathway in Hypoxia-Related Chronic Respiratory Diseases N Lüneburg, L Harbaum, J Hennigs BioMed research international 2014, 2014 | 47 | 2014 |
Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial … K Yuan, NY Shao, JK Hennigs, M Discipulo, ME Orcholski, E Shamskhou, ... The American Journal of Pathology 186 (9), 2500-2514, 2016 | 45 | 2016 |
Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018 A Olschewski, EM Berghausen, CA Eichstaedt, BK Fleischmann, E Grünig, ... International journal of cardiology 272, 4-10, 2018 | 39 | 2018 |
Role of Toll-like receptors and interferon regulatory factors in different experimental heart failure models of diverse etiology: IRF7 as novel cardiovascular stress-inducible … PM Becher, S Hinrichs, N Fluschnik, JK Hennigs, K Klingel, ... PloS one 13 (3), e0193844, 2018 | 34 | 2018 |