Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists B Wu, EYT Chien, CD Mol, G Fenalti, W Liu, V Katritch, R Abagyan, ... Science 330 (6007), 1066-1071, 2010 | 2143 | 2010 |
Regulation of protein function by glycosaminoglycans—as exemplified by chemokines TM Handel, Z Johnson, SE Crown, EK Lau, M Sweeney, AE Proudfoot Annu. Rev. Biochem. 74 (1), 385-410, 2005 | 641 | 2005 |
Structural basis for the attachment of a paramyxoviral polymerase to its template RL Kingston, DJ Hamel, LS Gay, FW Dahlquist, BW Matthews Proceedings of the National Academy of Sciences 101 (22), 8301-8306, 2004 | 229 | 2004 |
Interactions of chemokines with glycosaminoglycans DJ Hamel, AEI Proudfoot, TM Handel Methods in enzymology 461, 71-102, 2009 | 70 | 2009 |
The contact interface of a 120 kD CheA− CheW complex by methyl TROSY interaction spectroscopy DJ Hamel, FW Dahlquist Journal of the American Chemical Society 127 (27), 9676-9677, 2005 | 54 | 2005 |
Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA CM Quezada, DJ Hamel, C Gradinaru, AM Bilwes, FW Dahlquist, ... Journal of Biological Chemistry 280 (34), 30581-30585, 2005 | 52 | 2005 |
Human anti-CD27 antibodies, methods and uses J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ... US Patent 9,102,737, 2015 | 43 | 2015 |
Emerging concepts and approaches for chemokine-receptor drug discovery M O'Hayre, CL Salanga, TM Handel, DJ Hamel Expert opinion on drug discovery 5 (11), 1109-1122, 2010 | 38 | 2010 |
Chemical-Shift-Perturbation Mapping of the Phosphotransfer and Catalytic Domain Interaction in the Histidine Autokinase CheA from Thermotoga maritima, DJ Hamel, H Zhou, MR Starich, RA Byrd, FW Dahlquist Biochemistry 45 (31), 9509-9517, 2006 | 32 | 2006 |
A rapid and efficient way to obtain modified chemokines for functional and biophysical studies SJ Allen, DJ Hamel, TM Handel Cytokine 55 (2), 168-173, 2011 | 28 | 2011 |
A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer I Kufareva, B Stephens, CT Gilliland, B Wu, G Fenalti, D Hamel, ... Chemokines: Methods and Protocols, 93-127, 2013 | 25 | 2013 |
Methods of inhibiting T-cell mediated B-cell antibody production using anti-CD27 antibodies J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ... US Patent 10,301,392, 2019 | 22 | 2019 |
Homo‐and Hetero‐Oligomerization of Chemokines A Jansma, TM Handel, DJ Hamel Methods in enzymology 461, 31-50, 2009 | 17 | 2009 |
Structural Basis for the Localization of the Chemotaxis Phosphatase CheZ by CheAS S Hao, D Hamel, H Zhou, FW Dahlquist Journal of bacteriology 191 (18), 5842-5844, 2009 | 9 | 2009 |
Nucleic acid molecules encoding anti-CD27 antibodies J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ... US Patent 9,683,046, 2017 | 5 | 2017 |
The structure and dynamic properties of the complete histidine phosphotransfer domain of the chemotaxis specific histidine autokinase CheA from Thermotoga maritima A Vu, DJ Hamel, H Zhou, FW Dahlquist Journal of biomolecular NMR 51, 49-55, 2011 | 5 | 2011 |
Human Anti-CD27 Antibodies, Methods and Uses J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ... US Patent App. 14/790,144, 2015 | 4 | 2015 |
Chemokines, Part A T Handel, D Hamel Academic Press, 2009 | 3 | 2009 |
Antibodies that specifically bind PD-1 and methods of use Q Chen, S Cole, K Duffy, Y Guo, D Gardner, D Hamel, S Hitchcock, ... US Patent 10,995,149, 2021 | 2 | 2021 |
Antibodies that specifically bind PD-1 and methods of use Q Chen, S Cole, K Duffy, D Gardner, GUO Yanxia, D HAMEL, ... | 2 | 2018 |