关注
Damon J Hamel
Damon J Hamel
Nektar Therapeutics
在 nektar.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
B Wu, EYT Chien, CD Mol, G Fenalti, W Liu, V Katritch, R Abagyan, ...
Science 330 (6007), 1066-1071, 2010
21432010
Regulation of protein function by glycosaminoglycans—as exemplified by chemokines
TM Handel, Z Johnson, SE Crown, EK Lau, M Sweeney, AE Proudfoot
Annu. Rev. Biochem. 74 (1), 385-410, 2005
6412005
Structural basis for the attachment of a paramyxoviral polymerase to its template
RL Kingston, DJ Hamel, LS Gay, FW Dahlquist, BW Matthews
Proceedings of the National Academy of Sciences 101 (22), 8301-8306, 2004
2292004
Interactions of chemokines with glycosaminoglycans
DJ Hamel, AEI Proudfoot, TM Handel
Methods in enzymology 461, 71-102, 2009
702009
The contact interface of a 120 kD CheA− CheW complex by methyl TROSY interaction spectroscopy
DJ Hamel, FW Dahlquist
Journal of the American Chemical Society 127 (27), 9676-9677, 2005
542005
Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA
CM Quezada, DJ Hamel, C Gradinaru, AM Bilwes, FW Dahlquist, ...
Journal of Biological Chemistry 280 (34), 30581-30585, 2005
522005
Human anti-CD27 antibodies, methods and uses
J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ...
US Patent 9,102,737, 2015
432015
Emerging concepts and approaches for chemokine-receptor drug discovery
M O'Hayre, CL Salanga, TM Handel, DJ Hamel
Expert opinion on drug discovery 5 (11), 1109-1122, 2010
382010
Chemical-Shift-Perturbation Mapping of the Phosphotransfer and Catalytic Domain Interaction in the Histidine Autokinase CheA from Thermotoga maritima,
DJ Hamel, H Zhou, MR Starich, RA Byrd, FW Dahlquist
Biochemistry 45 (31), 9509-9517, 2006
322006
A rapid and efficient way to obtain modified chemokines for functional and biophysical studies
SJ Allen, DJ Hamel, TM Handel
Cytokine 55 (2), 168-173, 2011
282011
A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer
I Kufareva, B Stephens, CT Gilliland, B Wu, G Fenalti, D Hamel, ...
Chemokines: Methods and Protocols, 93-127, 2013
252013
Methods of inhibiting T-cell mediated B-cell antibody production using anti-CD27 antibodies
J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ...
US Patent 10,301,392, 2019
222019
Homo‐and Hetero‐Oligomerization of Chemokines
A Jansma, TM Handel, DJ Hamel
Methods in enzymology 461, 31-50, 2009
172009
Structural Basis for the Localization of the Chemotaxis Phosphatase CheZ by CheAS
S Hao, D Hamel, H Zhou, FW Dahlquist
Journal of bacteriology 191 (18), 5842-5844, 2009
92009
Nucleic acid molecules encoding anti-CD27 antibodies
J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ...
US Patent 9,683,046, 2017
52017
The structure and dynamic properties of the complete histidine phosphotransfer domain of the chemotaxis specific histidine autokinase CheA from Thermotoga maritima
A Vu, DJ Hamel, H Zhou, FW Dahlquist
Journal of biomolecular NMR 51, 49-55, 2011
52011
Human Anti-CD27 Antibodies, Methods and Uses
J Chen, J Fransson, N Fursov, D Hamel, T Malia, G Obmolova, T Ort, ...
US Patent App. 14/790,144, 2015
42015
Chemokines, Part A
T Handel, D Hamel
Academic Press, 2009
32009
Antibodies that specifically bind PD-1 and methods of use
Q Chen, S Cole, K Duffy, Y Guo, D Gardner, D Hamel, S Hitchcock, ...
US Patent 10,995,149, 2021
22021
Antibodies that specifically bind PD-1 and methods of use
Q Chen, S Cole, K Duffy, D Gardner, GUO Yanxia, D HAMEL, ...
22018
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