| PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation N Patsoukis, K Bardhan, P Chatterjee, D Sari, B Liu, LN Bell, ED Karoly, ... Nature communications 6 (1), 6692, 2015 | 1076 | 2015 |
| Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells Z Husain, Y Huang, P Seth, VP Sukhatme The Journal of Immunology 191 (3), 1486-1495, 2013 | 746 | 2013 |
| Targeting lactate dehydrogenase-a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells H Xie, J Hanai, JG Ren, L Kats, K Burgess, P Bhargava, S Signoretti, ... Cell metabolism 19 (5), 795-809, 2014 | 492 | 2014 |
| Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability CA Jones, NR London, H Chen, KW Park, D Sauvaget, RA Stockton, ... Nature medicine 14 (4), 448-453, 2008 | 464 | 2008 |
| Lactate is a natural suppressor of RLR signaling by targeting MAVS W Zhang, G Wang, ZG Xu, H Tu, F Hu, J Dai, Y Chang, Y Chen, Y Lu, ... Cell 178 (1), 176-189. e15, 2019 | 412 | 2019 |
| Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter X Wu, W Huang, PD Prasad, P Seth, DP Rajan, FH Leibach, J Chen, ... Journal of Pharmacology and Experimental Therapeutics 290 (3), 1482-1492, 1999 | 398 | 1999 |
| Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury A Masuzawa, KM Black, CA Pacak, M Ericsson, RJ Barnett, C Drumm, ... American Journal of Physiology-Heart and Circulatory Physiology 304 (7 …, 2013 | 367 | 2013 |
| Cloning and functional characterization of a σ receptor from rat brain P Seth, YJ Fei, HW Li, W Huang, FH Leibach, V Ganapathy Journal of neurochemistry 70 (3), 922-931, 1998 | 367 | 1998 |
| Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton H Hu, A Juvekar, CA Lyssiotis, EC Lien, JG Albeck, D Oh, G Varma, ... Cell 164 (3), 433-446, 2016 | 360 | 2016 |
| Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth B Wegiel, D Gallo, E Csizmadia, C Harris, J Belcher, GM Vercellotti, ... Cancer research 73 (23), 7009-7021, 2013 | 347 | 2013 |
| Modeling precision treatment of breast cancer A Daemen, OL Griffith, LM Heiser, NJ Wang, OM Enache, Z Sanborn, ... Genome biology 14, 1-14, 2013 | 335 | 2013 |
| LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer H Xie, VA Valera, MJ Merino, AM Amato, S Signoretti, WM Linehan, ... Molecular cancer therapeutics 8 (3), 626-635, 2009 | 287 | 2009 |
| roundabout4 is essential for angiogenesis in vivo VM Bedell, SY Yeo, KW Park, J Chung, P Seth, V Shivalingappa, J Zhao, ... Proceedings of the National Academy of Sciences 102 (18), 6373-6378, 2005 | 261 | 2005 |
| Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor P Seth, FH Leibach, V Ganapathy Biochemical and biophysical research communications 241 (2), 535-540, 1997 | 260 | 1997 |
| Lactate dehydrogenase activity drives hair follicle stem cell activation A Flores, J Schell, AS Krall, D Jelinek, M Miranda, M Grigorian, D Braas, ... Nature cell biology 19 (9), 1017-1026, 2017 | 252 | 2017 |
| Mutations of OCTN2, an Organic Cation/Carnitine Transporter, Lead to Deficient Cellular Carnitine Uptake in Primary Carnitine Deficiency NLS Tang, V Ganapathy, X Wu, J Hui, P Seth, PMP Yuen, TF Fok, ... Human molecular genetics 8 (4), 655-660, 1999 | 190 | 1999 |
| HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells IE Krop, D Sgroi, DA Porter, KL Lunetta, R LeVangie, P Seth, CM Kaelin, ... Proceedings of the National Academy of Sciences 98 (17), 9796-9801, 2001 | 179 | 2001 |
| Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen‐activated protein kinase (MAPK) and phosphatidylinositol‐3 … J Hanai, N Doro, AT Sasaki, S Kobayashi, LC Cantley, P Seth, ... Journal of cellular physiology 227 (4), 1709-1720, 2012 | 175 | 2012 |
| Targeting T cell metabolism for improvement of cancer immunotherapy T Le Bourgeois, L Strauss, HI Aksoylar, S Daneshmandi, P Seth, ... Frontiers in oncology 8, 237, 2018 | 162 | 2018 |
| Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells J Hanai, T Mammoto, P Seth, K Mori, SA Karumanchi, J Barasch, ... Journal of Biological Chemistry 280 (14), 13641-13647, 2005 | 161 | 2005 |
