| Single-cell–resolution map of human retinal pigment epithelium helps discover subpopulations with differential disease sensitivity D Ortolan, R Sharma, A Volkov, A Maminishkis, NA Hotaling, LA Huryn, ... Proceedings of the National Academy of Sciences 119 (19), e2117553119, 2022 | 47 | 2022 |
| Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model R Sharma, A George, M Nimmagadda, D Ortolan, BS Karla, Z Qureshy, ... Nature Communications 12 (1), 7293, 2021 | 39 | 2021 |
| CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization X Yang, L Zhao, MM Campos, M Abu-Asab, D Ortolan, N Hotaling, ... Elife 9, e55564, 2020 | 36 | 2020 |
| AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration KJ Miyagishima, R Sharma, M Nimmagadda, K Clore-Gronenborn, ... Communications biology 4 (1), 1360, 2021 | 25 | 2021 |
| Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity E Ghirardini, E Restelli, R Morini, I Bertani, D Ortolan, F Perrucci, D Pozzi, ... PLoS Pathogens 16 (7), e1008654, 2020 | 17 | 2020 |
| Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells R Sharma, D Bose, J Montford, D Ortolan, K Bharti STAR protocols 3 (3), 101582, 2022 | 15 | 2022 |
| Activation of Src family kinase ameliorates secretory trafficking in mutant prion protein cells E Restelli, V Capone, M Pozzoli, D Ortolan, E Quaglio, A Corbelli, ... Journal of Biological Chemistry 296, 2021 | 5 | 2021 |
| Choroid-resident macrophages maintain local vasculature and RPE integrity and spontaneously regenerate following depletion X Yang, L Zhao, MM Campos, M Abu-Asab, D Ortolan, N Hotaling, ... bioRxiv, 868430, 2019 | 2 | 2019 |
| Considerations for Developing an Autologous Induced Pluripotent Stem Cell (iPSC)-Derived Retinal Pigment Epithelium (RPE) Replacement Therapy D Bose, D Ortolan, M Farnoodian, R Sharma, K Bharti Cold Spring Harbor Perspectives in Medicine 14 (3), a041295, 2024 | | 2024 |
| Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies Z Esh, S Suresh, D Ortolan, M Farnoodian, D Bose, J Ryu, A Volkov, ... JoVE (Journal of Visualized Experiments), e65503, 2023 | | 2023 |
| Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis D Ortolan, A Volkov, A Maminishkis, R Sharma, K Bharti JoVE (Journal of Visualized Experiments), e64761, 2022 | | 2022 |
| Correction: Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity E Ghirardini, E Restelli, R Morini, I Bertani, D Ortolan, F Perrucci, D Pozzi, ... PLoS Pathogens 16 (12), e1009174, 2020 | | 2020 |
| Mutant prion proteins related to genetic prion diseases impair intracellular trafficking E Restelli, V Capone, M Pozzoli, D Ortolan, M Sallese, R Chiesa PRION 9, S5-S6, 2015 | | 2015 |
