Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 2206 | 2018 |
KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer W Liao, MJ Overman, AT Boutin, X Shang, DI Zhao, P Dey, J Li, G Wang, ... Cancer cell 35 (4), 559-572. e7, 2019 | 501 | 2019 |
Symbiotic macrophage-glioma cell interactions reveal synthetic lethality in PTEN-null glioma P Chen, D Zhao, J Li, X Liang, J Li, A Chang, VK Henry, Z Lan, DJ Spring, ... Cancer cell 35 (6), 868-884. e6, 2019 | 276 | 2019 |
Systematic functional annotation of somatic mutations in cancer PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ... Cancer cell 33 (3), 450-462. e10, 2018 | 275 | 2018 |
Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer D Zhao, X Lu, G Wang, Z Lan, W Liao, J Li, X Liang, JR Chen, S Shah, ... Nature 542 (7642), 484-488, 2017 | 207 | 2017 |
Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer A Alam, E Levanduski, P Denz, HS Villavicencio, M Bhatta, L Alhorebi, ... Cancer cell 40 (2), 153-167. e11, 2022 | 201 | 2022 |
Comprehensive T cell repertoire characterization of non-small cell lung cancer A Reuben, J Zhang, SH Chiou, RM Gittelman, J Li, WC Lee, J Fujimoto, ... Nature communications 11 (1), 603, 2020 | 194 | 2020 |
TCR repertoire intratumor heterogeneity in localized lung adenocarcinomas: an association with predicted neoantigen heterogeneity and postsurgical recurrence A Reuben, R Gittelman, J Gao, J Zhang, EC Yusko, CJ Wu, R Emerson, ... Cancer discovery 7 (10), 1088-1097, 2017 | 191 | 2017 |
Oncogenic KRAS-driven metabolic reprogramming in pancreatic cancer cells utilizes cytokines from the tumor microenvironment P Dey, J Li, J Zhang, S Chaurasiya, A Strom, H Wang, WT Liao, ... Cancer discovery 10 (4), 608-625, 2020 | 159 | 2020 |
Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma X Hu, J Fujimoto, L Ying, J Fukuoka, K Ashizawa, W Sun, A Reuben, ... Nature communications 10 (1), 2978, 2019 | 126 | 2019 |
Combination of PD-1 inhibitor and OX40 agonist induces tumor rejection and immune memory in mouse models of pancreatic cancer Y Ma, J Li, H Wang, Y Chiu, CV Kingsley, D Fry, SN Delaney, SC Wei, ... Gastroenterology 159 (1), 306-319. e12, 2020 | 118 | 2020 |
Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer P Hou, A Kapoor, Q Zhang, J Li, CJ Wu, J Li, Z Lan, M Tang, X Ma, ... Cancer discovery 10 (7), 1058-1077, 2020 | 113 | 2020 |
LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes J Li, X Dai, T Liu, PX Zhao Nucleic acids research 40 (D1), D1221-D1229, 2012 | 113 | 2012 |
p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways S Roy, KH Tomaszowski, JW Luzwick, S Park, J Li, M Murphy, ... Elife 7, e31723, 2018 | 96 | 2018 |
Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target X Le, MV Negrao, A Reuben, L Federico, L Diao, D McGrail, M Nilsson, ... Journal of thoracic oncology 16 (4), 583-600, 2021 | 89 | 2021 |
USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation P Hou, X Ma, Q Zhang, CJ Wu, W Liao, J Li, H Wang, J Zhao, X Zhou, ... Genes & development 33 (19-20), 1361-1366, 2019 | 86 | 2019 |
The Medicago sativa gene index 1.2: a web-accessible gene expression atlas for investigating expression differences between Medicago sativa subspecies JA O’Rourke, F Fu, B Bucciarelli, SS Yang, DA Samac, JAFS Lamb, ... BMC genomics 16, 1-17, 2015 | 78 | 2015 |
Chromatin regulator CHD1 remodels the immunosuppressive tumor microenvironment in PTEN-deficient prostate cancer D Zhao, L Cai, X Lu, X Liang, J Li, P Chen, M Ittmann, X Shang, S Jiang, ... Cancer discovery 10 (9), 1374-1387, 2020 | 76 | 2020 |
Neoadjuvant chemotherapy increases cytotoxic T cell, tissue resident memory T cell, and B cell infiltration in resectable NSCLC PO Gaudreau, MV Negrao, KG Mitchell, A Reuben, EM Corsini, J Li, ... Journal of Thoracic Oncology 16 (1), 127-139, 2021 | 71 | 2021 |
Telomere dysfunction activates YAP1 to drive tissue inflammation D Chakravarti, B Hu, X Mao, A Rashid, J Li, J Li, W Liao, EM Whitley, ... Nature communications 11 (1), 4766, 2020 | 71 | 2020 |