Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients MAE Rab, BA van Oirschot, J Bos, TH Merkx, ACW van Wesel, ... American journal of hematology 94 (5), 575-584, 2019 | 67 | 2019 |
AG-348 (mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and adenosine triphosphate levels over a broad … MAE Rab, BA Van Oirschot, PA Kosinski, J Hixon, K Johnson, ... Haematologica 106 (1), 238, 2021 | 58 | 2021 |
Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis R Huisjes, A Makhro, E Llaudet-Planas, L Hertz, P Petkova-Kirova, ... haematologica 105 (2), 338, 2020 | 40 | 2020 |
Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy MAE Rab, J Bos, BA van Oirschot, S van Straaten, PA Kosinski, ... Blood, The Journal of the American Society of Hematology 137 (21), 2997-3001, 2021 | 31 | 2021 |
Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in sickle cell disease: a phase 2, open-label study MJ van Dijk, MAE Rab, BA van Oirschot, J Bos, C Derichs, AW Rijneveld, ... American journal of hematology 97 (7), E226-E229, 2022 | 29 | 2022 |
Oxygen gradient ektacytometry‐derived biomarkers are associated with vaso‐occlusive crises and correlate with treatment response in sickle cell disease MAE Rab, CK Kanne, J Bos, BA van Oirschot, C Boisson, ME Houwing, ... American journal of hematology 96 (1), E29, 2021 | 26 | 2021 |
PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis PL Moura, BR Hawley, JGG Dobbe, GJ Streekstra, MAE Rab, P Bianchi, ... Haematologica 105 (6), e268, 2020 | 26 | 2020 |
Blood rheology biomarkers in sickle cell disease M Lu, MAE Rab, SS Shevkoplyas, VA Sheehan Experimental Biology and Medicine 245 (2), 155-165, 2020 | 21 | 2020 |
Methodological aspects of the oxygenscan in sickle cell disease: a need for standardization MAE Rab, CK Kanne, J Bos, C Boisson, BA van Oirschot, E Nader, ... American Journal of Hematology 95 (1), E5, 2020 | 20 | 2020 |
Mechanical Stress Induces Ca2+-Dependent Signal Transduction in Erythroblasts and Modulates Erythropoiesis F Aglialoro, A Abay, N Yagci, MAE Rab, L Kaestner, R van Wijk, ... International journal of molecular sciences 22 (2), 955, 2021 | 19 | 2021 |
Characterization of sickling during controlled automated deoxygenation with oxygen gradient ektacytometry MAE Rab, BA van Oirschot, J Bos, CK Kanne, VA Sheehan, EJ van Beers, ... JoVE (Journal of Visualized Experiments), e60213, 2019 | 18 | 2019 |
Persistent changes in circulating white blood cell populations after splenectomy MAE Rab, A Meerveld-Eggink, H van Velzen-Blad, D van Loon, ... International Journal of Hematology 107, 157-165, 2018 | 15 | 2018 |
Impaired Cytoskeletal and Membrane Biophysical Properties of Acanthocytes in Hypobetalipoproteinemia–A Case Study AS Cloos, LGM Daenen, M Maja, A Stommen, J Vanderroost, ... Frontiers in Physiology 12, 638027, 2021 | 12 | 2021 |
Methodological aspects of oxygen gradient ektacytometry in sickle cell disease: Effects of sample storage on outcome parameters in distinct patient subgroups C Boisson, MAE Rab, E Nader, C Renoux, BA van Oirschot, P Joly, R Fort, ... Clinical Hemorheology and Microcirculation 77 (4), 391-394, 2021 | 12 | 2021 |
Effects of genotypes and treatment on oxygenscan parameters in sickle cell disease C Boisson, MAE Rab, E Nader, C Renoux, C Kanne, J Bos, ... Cells 10 (4), 811, 2021 | 11 | 2021 |
A functional spleen contributes to afucosylated IgG in humans I Wojcik, DE Schmidt, LA de Neef, MAE Rab, B Meek, O de Weerdt, ... Scientific reports 11 (1), 24045, 2021 | 8 | 2021 |
Ektacytometry analysis of post-splenectomy red blood cell properties identifies cell membrane stability test as a novel biomarker of membrane health in hereditary spherocytosis MC Berrevoets, J Bos, R Huisjes, TH Merkx, BA Van Oirschot, ... Frontiers in Physiology 12, 641384, 2021 | 6 | 2021 |
Effect of cell age and membrane rigidity on red blood cell shape in capillary flow M Nouaman, A Darras, T John, G Simionato, MAE Rab, R van Wijk, ... Cells 12 (11), 1529, 2023 | 5 | 2023 |
Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis M Delamare, A Le Roy, M Pacault, L Schmitt, C Garrec, N Maaziz, ... Haematologica, 2023 | 4 | 2023 |
Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis V Karaghiannis, D Maric, C Garrec, N Maaziz, A Buffet, L Schmitt, ... Haematologica, 2023 | 4 | 2023 |