A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms H Tsugawa, R Nakabayashi, T Mori, Y Yamada, M Takahashi, A Rai, ... Nature methods 16 (4), 295-298, 2019 | 242 | 2019 |
5-Alkyl-1, 2, 3, 4-tetrahydroquinolines, new membrane-interacting lipophilic metabolites produced by combined culture of Streptomyces nigrescens and Tsukamurella pulmonis R Sugiyama, S Nishimura, T Ozaki, S Asamizu, H Onaka, H Kakeya Organic letters 17 (8), 1918-1921, 2015 | 81 | 2015 |
Post-translational formation of strained cyclophanes in bacteria TQN Nguyen, YW Tooh, R Sugiyama, TPD Nguyen, M Purushothaman, ... Nature Chemistry 12 (11), 1042-1053, 2020 | 77 | 2020 |
Retrograde sulfur flow from glucosinolates to cysteine in Arabidopsis thaliana R Sugiyama, R Li, A Kuwahara, R Nakabayashi, N Sotta, T Mori, T Ito, ... Proceedings of the National Academy of Sciences 118 (22), e2017890118, 2021 | 73 | 2021 |
Structure and Biological Activity of 8-Deoxyheronamide C from a Marine-Derived Streptomyces sp.: Heronamides Target Saturated Hydrocarbon Chains in Lipid … R Sugiyama, S Nishimura, N Matsumori, Y Tsunematsu, A Hattori, ... Journal of the American Chemical Society 136 (14), 5209-5212, 2014 | 64 | 2014 |
Leaf endoplasmic reticulum bodies identified in Arabidopsis rosette leaves are involved in defense against herbivory A Nakazaki, K Yamada, T Kunieda, R Sugiyama, MY Hirai, K Tamura, ... Plant physiology 179 (4), 1515-1524, 2019 | 58 | 2019 |
Atypical myrosinase as a mediator of glucosinolate functions in plants R Sugiyama, MY Hirai Frontiers in plant science 10, 1008, 2019 | 55 | 2019 |
Discovery and total synthesis of streptoaminals: antimicrobial [5, 5]‐spirohemiaminals from the combined‐culture of Streptomyces nigrescens and Tsukamurella pulmonis R Sugiyama, S Nishimura, T Ozaki, S Asamizu, H Onaka, H Kakeya Angewandte Chemie 128 (35), 10434-10438, 2016 | 50 | 2016 |
Asymmetric Total Synthesis of Heronamides A–C: Stereochemical Confirmation and Impact of Long‐Range Stereochemical Communication on the Biological Activity N Kanoh, S Itoh, K Fujita, K Sakanishi, R Sugiyama, Y Terajima, ... Chemistry–A European Journal 22 (25), 8586-8595, 2016 | 32 | 2016 |
Stereochemical reassignment of heronamide A, a polyketide macrolactam from Streptomyces sp. R Sugiyama, S Nishimura, H Kakeya Tetrahedron Letters 54 (12), 1531-1533, 2013 | 32 | 2013 |
The biosynthetic landscape of triceptides reveals radical SAM enzymes that catalyze cyclophane formation on Tyr-and His-containing motifs R Sugiyama, AFL Suarez, Y Morishita, TQN Nguyen, YW Tooh, ... Journal of the American Chemical Society 144 (26), 11580-11593, 2022 | 28 | 2022 |
Identification of the common biosynthetic gene cluster for both antimicrobial streptoaminals and antifungal 5-alkyl-1, 2, 3, 4-tetrahydroquinolines T Ozaki, R Sugiyama, M Shimomura, S Nishimura, S Asamizu, ... Organic & Biomolecular Chemistry 17 (9), 2370-2378, 2019 | 23 | 2019 |
Stereochemical assignment and biological evaluation of BE-14106 unveils the importance of one acetate unit for the antifungal activity of polyene macrolactams K Fujita, R Sugiyama, S Nishimura, N Ishikawa, MA Arai, M Ishibashi, ... Journal of Natural Products 79 (7), 1877-1880, 2016 | 19 | 2016 |
Glutathione degradation activity of γ‐glutamyl peptidase 1 manifests its dual roles in primary and secondary sulfur metabolism in Arabidopsis T Ito, T Kitaiwa, K Nishizono, M Umahashi, S Miyaji, S Agake, K Kuwahara, ... The Plant Journal 111 (6), 1626-1642, 2022 | 16 | 2022 |
Total synthesis of the proposed structure of heronamide C K Sakanishi, S Itoh, R Sugiyama, S Nishimura, H Kakeya, Y Iwabuchi, ... European Journal of Organic Chemistry 2014 (7), 1376-1380, 2014 | 16 | 2014 |
Chemical Interactions of Cryptic Actinomycete Metabolite 5‐Alkyl‐1, 2, 3, 4‐tetrahydroquinolines through Aggregate Formation R Sugiyama, T Nakatani, S Nishimura, K Takenaka, T Ozaki, S Asamizu, ... Angewandte Chemie 131 (38), 13620-13625, 2019 | 13 | 2019 |
Amphiol, an Antifungal Fungal Pigment from Pseudogymnoascus sp. PF1464 K Fujita, M Ikuta, S Nishimura, R Sugiyama, A Yoshimura, H Kakeya Journal of Natural Products 84 (4), 986-992, 2021 | 12 | 2021 |
Publisher Correction: A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms. H Tsugawa, R Nakabayashi, T Mori, Y Yamada, M Takahashi, A Rai, ... Nature Methods 16 (5), 446-446, 2019 | 3 | 2019 |
Characterization of γ-Glutamyl Peptidases and γ-Glutamyl Cyclotransferases for Glutathione Degradation in Arabidopsis T Ito, T Kitaiwa, K Nishizono, M Umahashi, S Miyaji, S Agake, K Kuwahara, ... BioRxiv, 2021.10. 29.466391, 2021 | 1 | 2021 |
Isolation of new indole alkaloid triglucoside from the aqueous extract of Uncaria rhynchophylla Y Koseki, H Nishimura, R Asano, K Aoki, L Shiyu, R Sugiyama, ... Journal of Natural Medicines, 1-8, 2024 | | 2024 |