| Tuning genetic control through promoter engineering H Alper, C Fischer, E Nevoigt, G Stephanopoulos Proceedings of the National Academy of Sciences 102 (36), 12678-12683, 2005 | 1103 | 2005 |
| Engineering yeast transcription machinery for improved ethanol tolerance and production H Alper, J Moxley, E Nevoigt, GR Fink, G Stephanopoulos Science 314 (5805), 1565-1568, 2006 | 1015 | 2006 |
| Machine learning-aided engineering of hydrolases for PET depolymerization H Lu, DJ Diaz, NJ Czarnecki, C Zhu, W Kim, R Shroff, DJ Acosta, ... Nature 604 (7907), 662-667, 2022 | 618 | 2022 |
| Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production J Blazeck, A Hill, L Liu, R Knight, J Miller, A Pan, P Otoupal, HS Alper Nature communications 5 (1), 3131, 2014 | 586 | 2014 |
| Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets H Alper, K Miyaoku, G Stephanopoulos Nature biotechnology 23 (5), 612-616, 2005 | 567 | 2005 |
| Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli H Alper, YS Jin, JF Moxley, G Stephanopoulos Metabolic engineering 7 (3), 155-164, 2005 | 566 | 2005 |
| Global transcription machinery engineering: a new approach for improving cellular phenotype H Alper, G Stephanopoulos Metabolic engineering 9 (3), 258-267, 2007 | 537 | 2007 |
| Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential? H Alper, G Stephanopoulos Nature Reviews Microbiology 7 (10), 715-723, 2009 | 469 | 2009 |
| Controlling promoter strength and regulation in Saccharomyces cerevisiae using synthetic hybrid promoters J Blazeck, R Garg, B Reed, HS Alper Biotechnology and bioengineering 109 (11), 2884-2895, 2012 | 348 | 2012 |
| Tuning gene expression in Yarrowia lipolytica by a hybrid promoter approach J Blazeck, L Liu, H Redden, H Alper Applied and environmental microbiology 77 (22), 7905-7914, 2011 | 348 | 2011 |
| Metabolic engineering of muconic acid production in Saccharomyces cerevisiae KA Curran, JM Leavitt, AS Karim, HS Alper Metabolic engineering 15, 55-66, 2013 | 344 | 2013 |
| Promoter engineering: recent advances in controlling transcription at the most fundamental level J Blazeck, HS Alper Biotechnology journal 8 (1), 46-58, 2013 | 342 | 2013 |
| Engineering of Promoter Replacement Cassettes for Fine-Tuning of Gene Expression in Saccharomyces cerevisiae E Nevoigt, J Kohnke, CR Fischer, H Alper, U Stahl, G Stephanopoulos Applied and environmental microbiology 72 (8), 5266-5273, 2006 | 289 | 2006 |
| Expanding the metabolic engineering toolbox: more options to engineer cells KE Tyo, HS Alper, GN Stephanopoulos TRENDS in Biotechnology 25 (3), 132-137, 2007 | 284 | 2007 |
| The development and characterization of synthetic minimal yeast promoters H Redden, HS Alper Nature communications 6 (1), 7810, 2015 | 261 | 2015 |
| Use of expression-enhancing terminators in Saccharomyces cerevisiae to increase mRNA half-life and improve gene expression control for metabolic engineering applications KA Curran, AS Karim, A Gupta, HS Alper Metabolic engineering 19, 88-97, 2013 | 252 | 2013 |
| Characterization of plasmid burden and copy number in Saccharomyces cerevisiae for optimization of metabolic engineering applications AS Karim, KA Curran, HS Alper FEMS yeast research 13 (1), 107-116, 2013 | 252 | 2013 |
| Exploiting biological complexity for strain improvement through systems biology G Stephanopoulos, H Alper, J Moxley Nature biotechnology 22 (10), 1261-1267, 2004 | 249 | 2004 |
| Short synthetic terminators for improved heterologous gene expression in yeast KA Curran, NJ Morse, KA Markham, AM Wagman, A Gupta, HS Alper ACS synthetic biology 4 (7), 824-832, 2015 | 238 | 2015 |
| Synthetic biology and molecular genetics in non-conventional yeasts: current tools and future advances JM Wagner, HS Alper Fungal Genetics and Biology 89, 126-136, 2016 | 214 | 2016 |
