Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ... Science 368 (6498), 1499-1504, 2020 | 1204 | 2020 |
Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody W Yin, Y Xu, P Xu, X Cao, C Wu, C Gu, X He, X Wang, S Huang, Q Yuan, ... Science 375 (6584), 1048-1053, 2022 | 229 | 2022 |
A complex structure of arrestin-2 bound to a G protein-coupled receptor W Yin, Z Li, M Jin, YL Yin, PW De Waal, K Pal, Y Yin, X Gao, Y He, J Gao, ... Cell research 29 (12), 971-983, 2019 | 185 | 2019 |
RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19 Y Jiang, W Yin, HE Xu Biochemical and biophysical research communications 538, 47-53, 2021 | 157 | 2021 |
Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin W Yin, X Luan, Z Li, Z Zhou, Q Wang, M Gao, X Wang, F Zhou, J Shi, ... Nature structural & molecular biology 28 (3), 319-325, 2021 | 128 | 2021 |
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19 C Wu, W Yin, Y Jiang, HE Xu Acta Pharmacologica Sinica 43 (12), 3021-3033, 2022 | 91 | 2022 |
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 Y Xie, W Yin, Y Zhang, W Shang, Z Wang, X Luan, G Tian, HA Aisa, Y Xu, ... Cell Research 31 (11), 1212-1214, 2021 | 88 | 2021 |
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist W Yin, XE Zhou, D Yang, PW de Waal, M Wang, A Dai, X Cai, CY Huang, ... Cell discovery 4 (1), 12, 2018 | 79 | 2018 |
Structural basis for the tethered peptide activation of adhesion GPCRs YQ Ping, P Xiao, F Yang, RJ Zhao, SC Guo, X Yan, X Wu, C Zhang, Y Lu, ... Nature 604 (7907), 763-770, 2022 | 77 | 2022 |
Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA. 2 variant compared to BA. 1 and their possible mouse origins Y Xu, C Wu, X Cao, C Gu, H Liu, M Jiang, X Wang, Q Yuan, K Wu, J Liu, ... Cell research 32 (7), 609-620, 2022 | 72 | 2022 |
Structures of full-length glycoprotein hormone receptor signalling complexes J Duan, P Xu, X Cheng, C Mao, T Croll, X He, J Shi, X Luan, W Yin, E You, ... Nature 598 (7882), 688-692, 2021 | 64 | 2021 |
Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Q Liu, D Yang, Y Zhuang, TI Croll, X Cai, A Dai, X He, J Duan, W Yin, ... Nature chemical biology 17 (12), 1238-1244, 2021 | 58 | 2021 |
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors P Ren, W Shang, W Yin, H Ge, L Wang, X Zhang, B Li, H Li, Y Xu, EH Xu, ... Acta Pharmacologica Sinica 43 (2), 483-493, 2022 | 53 | 2022 |
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor Y Wang, S Guo, Y Zhuang, Y Yun, P Xu, X He, J Guo, W Yin, HE Xu, X Xie, ... Nature Communications 12 (1), 5064, 2021 | 49 | 2021 |
Molecular basis for kinin selectivity and activation of the human bradykinin receptors YL Yin, C Ye, F Zhou, J Wang, D Yang, W Yin, MW Wang, HE Xu, Y Jiang Nature structural & molecular biology 28 (9), 755-761, 2021 | 41 | 2021 |
Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor S Ma, Y Chen, A Dai, W Yin, J Guo, D Yang, F Zhou, Y Jiang, MW Wang, ... Cell Research 31 (10), 1061-1071, 2021 | 38 | 2021 |
Molecular basis of ligand recognition and activation of human V2 vasopressin receptor F Zhou, C Ye, X Ma, W Yin, TI Croll, Q Zhou, X He, X Zhang, D Yang, ... Cell research 31 (8), 929-931, 2021 | 35 | 2021 |
Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor F Zhao, C Zhang, Q Zhou, K Hang, X Zou, Y Chen, F Wu, Q Rao, A Dai, ... Elife 10, e68719, 2021 | 32 | 2021 |
Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors J Duan, DD Shen, T Zhao, S Guo, X He, W Yin, P Xu, Y Ji, LN Chen, J Liu, ... Nature Communications 13 (1), 1364, 2022 | 25 | 2022 |
GPCR activation and GRK2 assembly by a biased intracellular agonist J Duan, H Liu, F Zhao, Q Yuan, Y Ji, X Cai, X He, X Li, J Li, K Wu, T Gao, ... Nature 620 (7974), 676-681, 2023 | 24 | 2023 |