Epigenetics in cancer S Sharma, TK Kelly, PA Jones Carcinogenesis 31 (1), 27-36, 2010 | 3423 | 2010 |
Epigenetic modifications as therapeutic targets TK Kelly, DD De Carvalho, PA Jones Nature biotechnology 28 (10), 1069, 2010 | 902 | 2010 |
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation TB Miranda, CC Cortez, CB Yoo, G Liang, M Abe, TK Kelly, VE Marquez, ... Molecular cancer therapeutics 8 (6), 1579-1588, 2009 | 706 | 2009 |
Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons D Willis, KW Li, JQ Zheng, JH Chang, A Smit, T Kelly, TT Merianda, ... Journal of Neuroscience 25 (4), 778-791, 2005 | 487 | 2005 |
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules TK Kelly, Y Liu, FD Lay, G Liang, BP Berman, PA Jones Genome research 22 (12), 2497-2506, 2012 | 469 | 2012 |
A functional role for intra-axonal protein synthesis during axonal regeneration from adult sensory neurons JQ Zheng, TK Kelly, B Chang, S Ryazantsev, AK Rajasekaran, KC Martin, ... Journal of Neuroscience 21 (23), 9291-9303, 2001 | 400 | 2001 |
DNA methylation screening identifies driver epigenetic events of cancer cell survival DD De Carvalho, S Sharma, JS You, SF Su, PC Taberlay, TK Kelly, ... Cancer cell 21 (5), 655-667, 2012 | 327 | 2012 |
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer PC Taberlay, AL Statham, TK Kelly, SJ Clark, PA Jones Genome research 24 (9), 1421-1432, 2014 | 212 | 2014 |
Polycomb-repressed genes have permissive enhancers that initiate reprogramming PC Taberlay, TK Kelly, CC Liu, JS You, DD De Carvalho, TB Miranda, ... Cell 147 (6), 1283-1294, 2011 | 205 | 2011 |
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome JS Pedersen, E Valen, AMV Velazquez, BJ Parker, M Rasmussen, ... Genome research 24 (3), 454-466, 2014 | 184 | 2014 |
Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation I Nakano, AA Paucar, R Bajpai, JD Dougherty, A Zewail, TK Kelly, KJ Kim, ... J Cell Biol 170 (3), 413-427, 2005 | 167 | 2005 |
H2A. Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes TK Kelly, TB Miranda, G Liang, BP Berman, JC Lin, A Tanay, PA Jones Molecular cell 39 (6), 901-911, 2010 | 166 | 2010 |
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes JS You, TK Kelly, DD De Carvalho, PC Taberlay, G Liang, PA Jones Proceedings of the National Academy of Sciences 108 (35), 14497-14502, 2011 | 164 | 2011 |
An alternative approach to ChIP-Seq normalization enables detection of genome-wide changes in histone H3 lysine 27 trimethylation upon EZH2 inhibition B Egan, CC Yuan, ML Craske, P Labhart, GD Guler, D Arnott, TM Maile, ... PloS one 11 (11), e0166438, 2016 | 149 | 2016 |
The role of DNA methylation in directing the functional organization of the cancer epigenome FD Lay, Y Liu, TK Kelly, H Witt, PJ Farnham, PA Jones, BP Berman Genome research 25 (4), 467-477, 2015 | 105 | 2015 |
A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation JP Saxe, H Wu, TK Kelly, ME Phelps, YE Sun, HI Kornblum, J Huang Chemistry & biology 14 (9), 1019-1030, 2007 | 83 | 2007 |
Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS S Karumbayaram, TK Kelly, AA Paucar, AJT Roe, JA Umbach, A Charles, ... Disease models & mechanisms 2 (3-4), 189-195, 2009 | 68 | 2009 |
Cell lineage and regional identity of cultured spinal cord neural stem cells and comparison to brain-derived neural stem cells TK Kelly, SL Karsten, DH Geschwind, HI Kornblum PLoS One 4 (1), e4213, 2009 | 60 | 2009 |
Circulating nucleosomes as potential markers to monitor COVID-19 disease progression E Cavalier, J Guiot, K Lechner, A Dutsch, M Eccleston, M Herzog, T Bygott, ... Frontiers in Molecular Biosciences 8, 600881, 2021 | 37 | 2021 |
Nucleosome Occupancy and Methylome Sequencing (NOMe-seq) FD Lay, TK Kelly, PA Jones DNA Methylation Protocols, 267-284, 2018 | 34 | 2018 |