| Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease M Wernig, JP Zhao, J Pruszak, E Hedlund, D Fu, F Soldner, V Broccoli, ... Proceedings of the National Academy of Sciences 105 (15), 5856-5861, 2008 | 1688 | 2008 |
| Single-cell RNA sequencing: technical advancements and biological applications E Hedlund, Q Deng Molecular aspects of medicine 59, 36-46, 2018 | 333 | 2018 |
| Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis J Nijssen, LH Comley, E Hedlund Acta neuropathologica 133, 863-885, 2017 | 311 | 2017 |
| Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling S Nichterwitz, G Chen, J Aguila Benitez, M Yilmaz, H Storvall, M Cao, ... Nature communications 7 (1), 12139, 2016 | 295 | 2016 |
| Genetic selection of sox1GFP‐expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation S Chung, BS Shin, E Hedlund, J Pruszak, A Ferree, UJ Kang, O Isacson, ... Journal of neurochemistry 97 (5), 1467-1480, 2006 | 189 | 2006 |
| The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons S Chung, E Hedlund, M Hwang, DW Kim, BS Shin, DY Hwang, UJ Kang, ... Molecular and Cellular Neuroscience 28 (2), 241-252, 2005 | 183 | 2005 |
| A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate PT Newton, L Li, B Zhou, C Schweingruber, M Hovorakova, M Xie, X Sun, ... Nature 567 (7747), 234-238, 2019 | 182 | 2019 |
| Cytochrome P450 in the brain; a review E Hedlund, JA Gustafsson, M Warner Current drug metabolism 2 (3), 245-263, 2001 | 180 | 2001 |
| Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an … E Hedlund, J Pruszak, T Lardaro, W Ludwig, A VInuela, KS Kim, ... Stem cells 26 (6), 1526-1536, 2008 | 155 | 2008 |
| Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development Q Deng, E Andersson, E Hedlund, Z Alekseenko, E Coppola, L Panman, ... Development 138 (16), 3399-3408, 2011 | 140 | 2011 |
| Cellular therapy to target neuroinflammation in amyotrophic lateral sclerosis F Rizzo, G Riboldi, S Salani, M Nizzardo, C Simone, S Corti, E Hedlund Cellular and Molecular Life Sciences 71, 999-1015, 2014 | 116 | 2014 |
| Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS I Allodi, L Comley, S Nichterwitz, M Nizzardo, C Simone, JA Benitez, ... Scientific reports 6 (1), 25960, 2016 | 110 | 2016 |
| Direct reprogramming of resident NG2 glia into neurons with properties of fast-spiking parvalbumin-containing interneurons M Pereira, M Birtele, S Shrigley, JA Benitez, E Hedlund, M Parmar, ... Stem cell reports 9 (3), 742-751, 2017 | 108 | 2017 |
| Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation K Rose, A Allan, S Gauldie, G Stapleton, L Dobbie, K Dott, C Martin, ... Journal of Biological Chemistry 276 (26), 23937-23944, 2001 | 106 | 2001 |
| Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection E Hedlund, M Karlsson, T Osborn, W Ludwig, O Isacson Brain 133 (8), 2313-2330, 2010 | 101 | 2010 |
| Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation G Chen, JP Schell, JA Benitez, S Petropoulos, M Yilmaz, B Reinius, ... Genome research 26 (10), 1342-1354, 2016 | 100 | 2016 |
| Altered perivascular fibroblast activity precedes ALS disease onset A Månberg, N Skene, F Sanders, M Trusohamn, J Remnestål, ... Nature medicine 27 (4), 640-646, 2021 | 91 | 2021 |
| REVIEW ARTILCE: Cell therapy and stem cells in animal models of motor neuron disorders E Hedlund, MP Hefferan, M Marsala, O Isacson European journal of neuroscience 26 (7), 1721-1737, 2007 | 88 | 2007 |
| Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS J Nijssen, Jik, Aguila Benitez, N Hoogstraten, Rein, Kee, E Hedlund Stem Cell Reports 11 (6), 1565-1578, 2018 | 87 | 2018 |
| Selection of embryonic stem cell-derived enhanced green fluorescent protein-positive dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene … E Hedlund, J Pruszak, A Ferree, A Viñuela, S Hong, O Isacson, KS Kim Stem Cells 25 (5), 1126-1135, 2007 | 83 | 2007 |
Qiaolin DengDept. Physiology and Pharmacology, Karolinska Instiutet在 ki.se 的电子邮件经过验证
