THEMATIC REVIEW The diversity of sex steroid action: novel functions of hydroxysteroid (17b) dehydrogenases as revealed by genetically modified mouse models T Saloniemi, H Jokela, L Strauss, P Pakarinen, M Poutanen J. Endocrinol 212, 27-40, 2012 | 118 | 2012 |
Analysis by LC–MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue MR Häkkinen, T Heinosalo, N Saarinen, T Linnanen, R Voutilainen, ... Journal of Pharmaceutical and Biomedical Analysis 152, 165-172, 2018 | 78 | 2018 |
Human hydroxysteroid (17-β) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts B Husen, K Huhtinen, T Saloniemi, J Messinger, HH Thole, M Poutanen Endocrinology 147 (11), 5333-5339, 2006 | 76 | 2006 |
Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions K Huhtinen, T Saloniemi-Heinonen, P Keski-Rahkonen, R Desai, ... The Journal of Clinical Endocrinology & Metabolism 99 (11), E2188-E2197, 2014 | 71 | 2014 |
Novel hydroxysteroid (17β) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice T Saloniemi, P Järvensivu, P Koskimies, H Jokela, T Lamminen, ... The American journal of pathology 176 (3), 1443-1451, 2010 | 53 | 2010 |
A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions M Gabriel, V Fey, T Heinosalo, P Adhikari, K Rytkönen, T Komulainen, ... Scientific data 7 (1), 284, 2020 | 48 | 2020 |
Personalized drug sensitivity screening for bladder cancer using conditionally reprogrammed patient-derived cells K Kettunen, PJ Boström, T Lamminen, T Heinosalo, G West, I Saarinen, ... European Urology 76 (4), 430-434, 2019 | 37 | 2019 |
Human HSD17B1 expression masculinizes transgenic female mice T Saloniemi, M Welsh, T Lamminen, P Saunders, S Mäkelä, T Streng, ... Molecular and Cellular Endocrinology 301 (1-2), 163-168, 2009 | 36 | 2009 |
RGD motifs on the surface of baculovirus enhance transduction of human lung carcinoma cells H Matilainen, AR Mäkelä, R Riikonen, T Saloniemi, E Korhonen, T Hyypiä, ... Journal of biotechnology 125 (1), 114-126, 2006 | 36 | 2006 |
Activation of Androgens by Hydroxysteroid (17β) Dehydrogenase 1 in Vivo as a Cause of Prenatal Masculinization and Ovarian Benign Serous Cystadenomas T Saloniemi, T Lamminen, K Huhtinen, M Welsh, P Saunders, H Kujari, ... Molecular Endocrinology 21 (11), 2627-2636, 2007 | 35 | 2007 |
Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis T Heinosalo, M Gabriel, L Kallio, P Adhikari, K Huhtinen, TD Laajala, ... Human reproduction 33 (5), 817-831, 2018 | 30 | 2018 |
Truncated forms of viral VP2 proteins fused to EGFP assemble into fluorescent parvovirus-like particles L Gilbert, J Toivola, O Välilehto, T Saloniemi, C Cunningham, D White, ... Journal of nanobiotechnology 4, 1-12, 2006 | 29 | 2006 |
Role of hydroxysteroid (17beta) dehydrogenase type 1 in reproductive tissues and hormone-dependent diseases T Heinosalo, N Saarinen, M Poutanen Molecular and cellular endocrinology 489, 9-31, 2019 | 27 | 2019 |
Ovarian endometriosis signatures established through discovery and directed mass spectrometry analysis AP Vehmas, D Muth-Pawlak, K Huhtinen, T Saloniemi-Heinonen, ... Journal of proteome research 13 (11), 4983-4994, 2014 | 25 | 2014 |
Europium nanoparticle-based sialyl-tn monoclonal antibody discriminates epithelial ovarian Cancer–Associated CA125 from benign sources K Gidwani, N Nadeem, K Huhtinen, H Kekki, T Heinosalo, J Hynninen, ... Journal of Applied Laboratory Medicine 4 (3), 299-310, 2019 | 21 | 2019 |
Sex steroid-dependent and-independent action of hydroxysteroid (17β) dehydrogenase 2: evidence from transgenic female mice ZY Shen, T Saloniemi, A Ronnblad, P Järvensivu, P Pakarinen, ... Endocrinology 150 (11), 4941-4949, 2009 | 19 | 2009 |
In vivo mouse model for analysis of hydroxysteroid (17β) dehydrogenase 1 inhibitors T Lamminen, T Saloniemi, K Huhtinen, P Koskimies, J Messinger, ... Molecular and cellular endocrinology 301 (1-2), 158-162, 2009 | 17 | 2009 |
Transcriptomic responses to hypoxia in endometrial and decidual stromal cells KT Rytkönen, T Heinosalo, M Mahmoudian, X Ma, A Perheentupa, LL Elo, ... Reproduction 160 (1), 39-51, 2020 | 14 | 2020 |
HSD17B1 expression enhances estrogen signaling stimulated by the low active estrone, evidenced by an estrogen responsive element-driven reporter gene in vivo P Järvensivu, T Saloniemi-Heinonen, M Awosanya, P Koskimies, ... Chemico-Biological Interactions 234, 126-134, 2015 | 13 | 2015 |
Exploratory Analysis of CA125-MGL and–STn Glycoforms in the Differential Diagnostics of Pelvic Masses L Salminen, N Nadeem, AL Rolfsen, A Dørum, TD Laajala, S Grènman, ... The journal of applied laboratory medicine 5 (2), 263-272, 2020 | 10 | 2020 |