| Modulation of lanosterol synthase drives 24, 25-epoxysterol synthesis and oligodendrocyte formation Z Hubler, RM Friedrich, JL Sax, D Allimuthu, F Gao, AM Rivera-León, ... Cell chemical biology 28 (6), 866-875. e5, 2021 | 21 | 2021 |
| Inspirations from tetrafibricin and related polyketides: new methods and strategies for 1, 5-polyol synthesis RM Friedrich, GK Friestad Natural product reports 37 (9), 1229-1261, 2020 | 19 | 2020 |
| Unified Strategy for 1, 5, 9-and 1, 5, 7-Triols via Configuration-Encoded 1, 5-Polyol Synthesis: Preparation and Coupling of C15–C25 and C26–C40 Fragments of Tetrafibricin RM Friedrich, JQ Bell, A Garcia, Z Shen, GK Friestad The Journal of Organic Chemistry 83 (22), 13650-13669, 2018 | 16 | 2018 |
| Inhibition of SC4MOL and HSD17B7 shifts cellular sterol composition and promotes oligodendrocyte formation MJ Pleshinger, RM Friedrich, Z Hubler, AM Rivera-León, F Gao, D Yan, ... RSC Chemical Biology 3 (1), 56-68, 2022 | 12 | 2022 |
| Unified Strategy for 1, 5, 9-and 1, 5, 7-Triols via Configuration-Encoded 1, 5-Polyol Synthesis: Enantioselective Preparation of γ-Sulfonyl-α-silyloxyaldehydes and Iterative … RM Friedrich, G Sreenilayam, J Hackbarth, GK Friestad The Journal of Organic Chemistry 83 (22), 13636-13649, 2018 | 10 | 2018 |
| Access to an anti,syn‐1,5,7‐Triol by Configuration‐Encoded 1,5‐Polyol Synthesis: The C15–C25 Fragment of Tetrafibricin RM Friedrich, GK Friestad European Journal of Organic Chemistry 2017 (14), 1961-1964, 2017 | 10 | 2017 |
| Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation YF Chen, M Ghazala, RM Friedrich, BA Cordova, FN Petroze, ... Nature Chemical Biology, 1-12, 2024 | 4 | 2024 |
| C646 degrades Exportin-1 to modulate p300 chromatin occupancy and function YF Chen, A Rahman, JL Sax, MJA Pleshinger, RM Friedrich, DJ Adams Cell Chemical Biology 31 (7), 1363-1372. e8, 2024 | 1 | 2024 |
| Electrophile Determines Cellular Phenotypes among XPO1-Targeting Small Molecules YF Chen, Y Shen, DF Yan, M Ghazala, MA Scemama de Gialluly, ... Journal of Medicinal Chemistry 67 (14), 12033-12054, 2024 | 1 | 2024 |
| Access to the C15-C40 Fragment of Tetrafibricin via Configuration-Encoded 1, 5-Polyol Methodology RM Friedrich The University of Iowa, 2017 | | 2017 |
| Optimized route to the tetrafibricin C15-C25 fragment and feasibility studies on fragment coupling R Friedrich, J Bell, A Garcia, Z Shen, G Friestad ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
| Configuration-encoded 1, 5-polyol synthesis: Access to the anti, syn-1, 5, 7-triol within the C15-C25 fragment of tetrafibricin R Friedrich, G Friestad ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |
