关注
Zoltan Dekan
Zoltan Dekan
Institute for Molecular Bioscience, The University of Queensland
在 imb.uq.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
JD Osteen, V Herzig, J Gilchrist, JJ Emrick, C Zhang, X Wang, J Castro, ...
Nature 534 (7608), 494-499, 2016
2912016
Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a
JR Deuis, Z Dekan, JS Wingerd, JJ Smith, NR Munasinghe, RF Bhola, ...
Scientific reports 7 (1), 40883, 2017
1462017
Modulating oxytocin activity and plasma stability by disulfide bond engineering
M Muttenthaler, A Andersson, AD de Araujo, Z Dekan, RJ Lewis, ...
Journal of medicinal chemistry 53 (24), 8585-8596, 2010
1352010
Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain
AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ...
Nature communications 5 (1), 3165, 2014
1342014
Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain
JR Deuis, JS Wingerd, Z Winter, T Durek, Z Dekan, SR Sousa, ...
Toxins 8 (3), 78, 2016
1152016
α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure
Z Dekan, I Vetter, NL Daly, DJ Craik, RJ Lewis, PF Alewood
Journal of the American Chemical Society 133 (40), 15866-15869, 2011
922011
Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens
FC Cardoso, Z Dekan, KJ Rosengren, A Erickson, I Vetter, JR Deuis, ...
Molecular pharmacology 88 (2), 291-303, 2015
912015
A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain
J Gui, B Liu, G Cao, AM Lipchik, M Perez, Z Dekan, M Mobli, NL Daly, ...
Current Biology 24 (5), 473-483, 2014
752014
Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels
I Vetter, Z Dekan, O Knapp, DJ Adams, PF Alewood, RJ Lewis
Biochemical pharmacology 84 (4), 540-548, 2012
672012
Total synthesis of human hepcidin through regioselective disulfide‐bond formation by using the safety‐catch cysteine protecting group 4, 4′‐dimethylsulfinylbenzhydryl
Z Dekan, M Mobli, MW Pennington, E Fung, E Nemeth, PF Alewood
Angewandte Chemie 126 (11), 2975-2978, 2014
542014
Antiallodynic effects of the selective NaV1. 7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen
A Mueller, H Starobova, M Morgan, Z Dekan, O Cheneval, CI Schroeder, ...
Pain 160 (8), 1766-1780, 2019
532019
Modulatory features of the novel spider toxin μ‐TRTX‐Df1a isolated from the venom of the spider Davus fasciatus
FC Cardoso, Z Dekan, JJ Smith, JR Deuis, I Vetter, V Herzig, PF Alewood, ...
British journal of pharmacology 174 (15), 2528-2544, 2017
522017
PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold
B Madio, S Peigneur, YKY Chin, BR Hamilton, ST Henriques, JJ Smith, ...
Cellular and molecular life sciences 75, 4511-4524, 2018
452018
Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic sodium channel NaV1. 8
JR Deuis, Z Dekan, MC Inserra, TH Lee, MI Aguilar, DJ Craik, RJ Lewis, ...
Journal of Biological Chemistry 291 (22), 11829-11842, 2016
432016
A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor
Z Dekan, S Sianati, A Yousuf, KJ Sutcliffe, A Gillis, C Mallet, P Singh, ...
Proceedings of the National Academy of Sciences 116 (44), 22353-22358, 2019
422019
Δ‐Myrtoxin‐Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane‐disrupting, and nociceptive activities
Z Dekan, SJ Headey, M Scanlon, BA Baldo, TH Lee, MI Aguilar, JR Deuis, ...
Angewandte Chemie International Edition 56 (29), 8495-8499, 2017
322017
Conotoxin Φ‐MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti‐apoptotic activity
AH Jin, Z Dekan, MJ Smout, D Wilson, S Dutertre, I Vetter, RJ Lewis, ...
Angewandte Chemie International Edition 56 (47), 14973-14976, 2017
292017
Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions
A Mueller, Z Dekan, Q Kaas, AJ Agwa, H Starobova, PF Alewood, ...
ACS Pharmacology & Translational Science 3 (3), 535-546, 2020
252020
Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans
AA Walker, SD Robinson, JPV Paluzzi, DJ Merritt, SA Nixon, CI Schroeder, ...
Proceedings of the National Academy of Sciences 118 (18), e2023815118, 2021
242021
Olfactory bulb‐targeted quantum dot (QD) bioconjugate and Kv1. 3 blocking peptide improve metabolic health in obese male mice
AB Schwartz, A Kapur, Z Huang, R Anangi, JM Spear, S Stagg, E Fardone, ...
Journal of neurochemistry 157 (6), 1876-1896, 2021
222021
系统目前无法执行此操作,请稍后再试。
文章 1–20