The clinical landscape for AAV gene therapies I Phase, IIP IIPhase II, III Phase III nature reviews| Drug DIScoVery 20, 173, 2021 | 386 | 2021 |
Magnesium sensing via LFA-1 regulates CD8+ T cell effector function J Lötscher, AAM i Líndez, N Kirchhammer, E Cribioli, GMPG Attianese, ... Cell 185 (4), 585-602. e29, 2022 | 127 | 2022 |
A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors M Brams, A Pandya, D Kuzmin, R Van Elk, L Krijnen, JL Yakel, V Tsetlin, ... PLoS biology 9 (3), e1001034, 2011 | 123 | 2011 |
An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors S Haeger, D Kuzmin, S Detro-Dassen, N Lang, M Kilb, V Tsetlin, H Betz, ... Nature structural & molecular biology 17 (1), 90-98, 2010 | 106 | 2010 |
Assembly of nicotinic and other Cys‐loop receptors V Tsetlin, D Kuzmin, I Kasheverov Journal of neurochemistry 116 (5), 734-741, 2011 | 89 | 2011 |
Spider toxin inhibits gating pore currents underlying periodic paralysis R Männikkö, ZO Shenkarev, MG Thor, AA Berkut, MY Myshkin, ... Proceedings of the National Academy of Sciences 115 (17), 4495-4500, 2018 | 34 | 2018 |
Computer modeling of binding of diverse weak toxins to nicotinic acetylcholine receptors DY Mordvitsev, YL Polyak, DA Kuzmin, OV Levtsova, YV Tourleigh, ... Computational Biology and Chemistry 31 (2), 72-81, 2007 | 29 | 2007 |
Analogue closed-loop optogenetic modulation of hippocampal pyramidal cells dissociates gamma frequency and amplitude E Nicholson, DA Kuzmin, M Leite, TE Akam, DM Kullmann Elife 7, e38346, 2018 | 21 | 2018 |
Binding-site mutations in the [alpha] 1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator T Schumann, J Grudzinska, D Kuzmin, H Betz, B Laube Neuropharmacology 56 (1), 310-317, 2009 | 10 | 2009 |
A model for short [alpha]-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo Californica DY Mordvintsev, YL Polyak, DA Kuzmine, OV Levtsova, YV Tourleigh, ... Journal of Molecular Neuroscience 30 (1-2), 71, 2006 | 7 | 2006 |
van 14 der Loo JCM, Johnstone EC. The clinical landscape for aav gene therapies DA Kuzmin, MV Shutova, NR Johnston, OP Smith, VV Fedorin, ... Nat Rev 15 Drug Discov 20, 173-174, 2021 | 5 | 2021 |
Inhibitory glycine receptors S Dutertre, D Kuzmin, B Laube, H Betz Springer, 2011 | 2 | 2011 |
A Systematic Review of Clinical Safety and Efficacy of AAV Gene Therapies DA Kuzmin, NR Johnston, OP Smith, MV Shutova, YM Kukushkin, ... Molecular Therapy 28 (4), 559-559, 2020 | 1 | 2020 |
Russia-focused venture capital supports in-bound technology transfer and company building: An analysis of investment trends and outcomes. JM Garvey, S Kerner, A Tillmann, D Kuzmin Journal of Commercial Biotechnology 20 (1), 2014 | 1 | 2014 |
Correlation of renal solute-free water reabsorption and energy of interaction of vasotocin analogs with V2 receptor AV Kutina, TA Karavashkina, EI Shakhmatova, J Gao, DY Mordvintsev, ... Biology Bulletin 38, 615-621, 2011 | 1 | 2011 |
Analog closed-loop modulation of hippocampal pyramidal cells dissociates gamma frequency and amplitude E Nicholson, DA Kuzmin, M Leite, TE Akam, DM Kullmann bioRxiv, 279588, 2018 | | 2018 |
Extracellular and membrane domains in structure and function of Cys-loop receptors V Tsetlin, I Kasheverov, I Shelukhina, D Kuzmin, G Schmalzing, B Laube, ... JOURNAL OF NEUROCHEMISTRY 113, 29-29, 2010 | | 2010 |
Aromatic Interfaces between Transmembrane Helices M1/M4 and M3/M4 Play a Key Role in Cys-loop Receptor Assembly S Haeger, D Kuzmin, S Detro-Dassen, N Lang, M Kilb, V Tsetlin, H Betz, ... Biophysical Journal 98, 417, 2010 | | 2010 |
Polypeptide and peptide neurotoxins for identification of nicotinic acetylcholine receptors and for study of their structure IE Kasheverov, YN Utkin, IV Shelukhina, EV Kryukova, DA Kuzmin, ... Biochemistry (Biokhimiya). Supplemental Series A, Membrane and Cell Biology …, 2009 | | 2009 |
Modeling of the whole ligand-free alpha1 glycine receptor with closed channel and simulation of the strychnine binding. DA Kuzmine, DY Mordvintsev, OV Levtsova, KB Tereshkina, B Laube, ... | | |