Pannexin 1 and pannexin 3 channels regulate skeletal muscle myoblast proliferation and differentiation S Langlois, X Xiang, K Young, BJ Cowan, S Penuela, KN Cowan Journal of Biological Chemistry 289 (44), 30717-30731, 2014 | 73 | 2014 |
IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1 MD Faye, ST Beug, TE Graber, N Earl, X Xiang, B Wild, S Langlois, ... Oncogene 34 (12), 1532-1541, 2015 | 55 | 2015 |
Identification of pannexin 1-regulated genes, interactome, and pathways in rhabdomyosarcoma and its tumor inhibitory interaction with AHNAK X Xiang, S Langlois, ME St-Pierre, A Blinder, P Charron, TE Graber, ... Oncogene 40 (10), 1868-1883, 2021 | 18 | 2021 |
Pannexin 1 inhibits rhabdomyosarcoma progression through a mechanism independent of its canonical channel function X Xiang, S Langlois, ME St-Pierre, JF Barré, D Grynspan, B Purgina, ... Oncogenesis 7 (11), 89, 2018 | 18 | 2018 |
Induction of an alternative mRNA 5′ leader enhances translation of the ciliopathy gene Inpp5e and resistance to oncolytic virus infection HD Hoang, TE Graber, JJ Jia, N Vaidya, VH Gilchrist, X Xiang, W Li, ... Cell Reports 29 (12), 4010-4023. e5, 2019 | 17 | 2019 |
Quercetin induces pannexin 1 expression via an alternative transcript with a translationally active 5′ leader in rhabdomyosarcoma X Xiang, HD Hoang, VH Gilchrist, S Langlois, T Alain, KN Cowan Oncogenesis 11 (1), 9, 2022 | 9 | 2022 |
Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cells W Liu, J Jiang, Z Li, Y Xiao, S Zhou, D Wang, Y Zou, T Liu, K Li, H Liang, ... Theranostics 14 (8), 3339, 2024 | 3 | 2024 |
The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis J Jiang, X Shao, W Liu, M Wang, Q Li, M Wang, Y Xiao, K Li, H Liang, ... Cell Reports 43 (7), 2024 | 2 | 2024 |
Inhibition of Panx1 channels reduces the Malignant properties of human high-risk neuroblastoma S Langlois, ME St-Pierre, SH Holland, X Xiang, E Freeman, H Mohamed, ... Journal of Cancer 14 (5), 689, 2023 | 2 | 2023 |
Pannexin 1 regulates rhabdomyosarcoma tumor growth: a potential novel therapeutic target X Xiang, S Langlois, ME St-Pierre, J Barre, T Le Pham, KN Cowan Cancer Research 76 (14_Supplement), 1276-1276, 2016 | 2 | 2016 |
The reovirus variant RP116 is oncolytic in immunocompetent models and generates reduced neutralizing antibodies to Type 3 Dearing KH Song, X Xiang, SH Lee, JK Woo, G Enkhtaivan, CR Giraldo, YR Lee, ... Molecular Therapy Oncology 32 (3), 2024 | 1 | 2024 |
Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging S Zhou, Z Li, X Li, Y Ye, M Wang, J Jiang, L Tao, Y Wang, CT Tung, ... Journal of Advanced Research, 2024 | 1 | 2024 |
High-Pressure Delivery of Oncolytic Viruses via Needle-Free Injection Preserves Therapeutic Activity A Said, HD Hoang, N Earl, X Xiang, N Siddiqui, M Côté, T Alain Cancers 15 (23), 5655, 2023 | 1 | 2023 |
Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1 HD Hoang, A Said, N Vaidya, VH Gilchrist, K Malone, U Kabilan, ... Journal for Immunotherapy of Cancer 11 (3), 2023 | 1 | 2023 |
Tumour-suppressive Effects of Pannexin 1 and its Mechanism of Action and Regulation in Rhabdomyosarcoma X Xiang Université d'Ottawa/University of Ottawa, 2021 | | 2021 |
3. CHAPTER THREE: IDENTIFICATION OF PANNEXIN 1 REGULATED GENES, INTERACTOME, AND PATHWAYS IN RHABDOMYOARCOMA AND ITS TUMOR INHIBITORY INTERACTION WITH AHNAK X Xiang, S Langlois, ME St-Pierre, A Blinder, P Charron, TE Graber, ... Tumour-suppressive Effects of Pannexin 1 and its Mechanism of Action and …, 2021 | | 2021 |
4. CHAPTER FOUR: QUERCETIN INDUCES PANNEXIN 1 EXPRESSION VIA AN ALTERNATIVE TRANSCRIPT WITH A TRANSLATIONALLY ACTIVE 5’LEADER IN RHABDOMYOSARCOMA X Xiang, HD Hoang, V Gilchrist, S Langlois, T Alain, KN Cowan Tumour-suppressive Effects of Pannexin 1 and its Mechanism of Action and …, 2021 | | 2021 |
Pannexin 1 is down-regulated in rhabdomyosarcoma and negatively regulates tumor growth X Xiang, S Langlois, J Barre, MS Pierre, TL Pham, KN Cowan MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Characterization of the cellular inhibitor of apoptosis 1 (cIAP1) IRES trans-acting factors and their contribution to apoptotic resistance in rhabdomyosarcomas MD Faye, TE Graber, S Beug, X Xiang, B Wild, S Langlois, KN Cowan, ... Cancer Research 74 (19_Supplement), 4256-4256, 2014 | | 2014 |