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Steven Leach
Steven Leach
Professor of Molecular and Systems Biology, Dartmouth College
在 dartmouth.edu 的电子邮件经过验证
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引用次数
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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
46412008
A draft map of the human proteome
MS Kim, SM Pinto, D Getnet, RS Nirujogi, SS Manda, R Chaerkady, ...
Nature 509 (7502), 575-581, 2014
24512014
EMT and dissemination precede pancreatic tumor formation
AD Rhim, ET Mirek, NM Aiello, A Maitra, JM Bailey, F McAllister, ...
Cell 148 (1), 349-361, 2012
23132012
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
19432015
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
VP Balachandran, M Łuksza, JN Zhao, V Makarov, JA Moral, R Remark, ...
Nature 551 (7681), 512-516, 2017
10112017
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
Y Miyamoto, A Maitra, B Ghosh, U Zechner, P Argani, ...
Cancer cell 3 (6), 565-576, 2003
8442003
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene …
P Argani, C Iacobuzio-Donahue, B Ryu, C Rosty, M Goggins, RE Wilentz, ...
Clinical cancer research 7 (12), 3862-3868, 2001
7172001
Rationale for en bloc vein resection in the treatment of pancreatic adenocarcinoma adherent to the superior mesenteric-portal vein confluence
GM Fuhrman, SD Leach, CA Staley, JC Cusack, C Charnsangavej, ...
Annals of surgery 223 (2), 154-162, 1996
5281996
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
N Habbe, G Shi, RA Meguid, V Fendrich, F Esni, H Chen, G Feldmann, ...
Proceedings of the National Academy of Sciences 105 (48), 18913-18918, 2008
4702008
Mutation detection in patients with advanced cancer by universal sequencing of cancer-related genes in tumor and normal DNA vs guideline-based germline testing
D Mandelker, L Zhang, Y Kemel, ZK Stadler, V Joseph, A Zehir, ...
Jama 318 (9), 825-835, 2017
4592017
EUS, PET, and CT scanning for evaluation of pancreatic adenocarcinoma
HR Mertz, P Sechopoulos, D Delbeke, SD Leach
Gastrointestinal endoscopy 52 (3), 367-371, 2000
4412000
Pancreatic cancer
TP Yeo, RH Hruban, SD Leach, RE Wilentz, TA Sohn, SE Kern, ...
Current problems in cancer 26 (4), 176-275, 2002
4242002
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates
AL Means, IM Meszoely, K Suzuki, Y Miyamoto, AK Rustgi, RJ Coffey Jr, ...
Oxford University Press for The Company of Biologists Limited 132 (16), 3767 …, 2005
4202005
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase
H Pisharath, JM Rhee, MA Swanson, SD Leach, MJ Parsons
Mechanisms of development 124 (3), 218-229, 2007
4072007
Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma
P Argani, C Rosty, RE Reiter, RE Wilentz, SR Murugesan, SD Leach, ...
Cancer research 61 (11), 4320-4324, 2001
4062001
Survival following pancreaticoduodenectomy with resection of the superior mesenteric–portal vein confluence for adenocarcinoma of the pancreatic head
SD Leach, JE Lee, C Charnsangavej, KR Cleary, AM Lowy, CJ Fenoglio, ...
British Journal of Surgery 85 (5), 611-617, 1998
3961998
Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish
JM Davison, CM Akitake, MG Goll, JM Rhee, N Gosse, H Baier, ...
Developmental biology 304 (2), 811-824, 2007
3952007
Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia
F McAllister, JM Bailey, J Alsina, CJ Nirschl, R Sharma, H Fan, Y Rattigan, ...
Cancer cell 25 (5), 621-637, 2014
3912014
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway
OA Kent, RR Chivukula, M Mullendore, EA Wentzel, G Feldmann, KH Lee, ...
Genes & development 24 (24), 2754-2759, 2010
3592010
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
BM Desai, J Oliver-Krasinski, DD De Leon, C Farzad, N Hong, SD Leach, ...
The Journal of clinical investigation 117 (4), 971-977, 2007
3592007
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